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Radiography is often used to probe complex, evolving density fields in dynamic systems and in so doing gain insight into the underlying physics. This technique has been used in numerous fields including materials science, shock physics,…

In this study we explore the possibility to use deep learning for the reconstruction of phase images from 4D scanning transmission electron microscopy (4D-STEM) data. The process can be divided into two main steps. First, the complex…

Materials Science · Physics 2023-02-15 Thomas Friedrich , Chu-Ping Yu , Jo Verbeeck , Sandra Van Aert

Macromolecules change their shape (conformation) in the process of carrying out their functions. The imaging by cryo-electron microscopy of rapidly-frozen, individual copies of macromolecules (single particles) is a powerful and general…

Biomolecules · Quantitative Biology 2022-11-22 Bogdan Toader , Fred J. Sigworth , Roy R. Lederman

Single-molecule experimental techniques track the real-time dynamics of molecules by recording a small number of experimental observables. Following these observables provides a coarse-grained, low-dimensional representation of the…

Computational Physics · Physics 2021-02-03 Maximilian Topel , Andrew L. Ferguson

With X-ray free-electron lasers (XFELs), it is possible to determine the three-dimensional structure of noncrystalline nanoscale particles using X-ray single-particle imaging (SPI) techniques at room temperature. Classifying SPI scattering…

Machine Learning · Computer Science 2023-02-15 Cong Wang , Eric Florin , Hsing-Yin Chang , Jana Thayer , Chun Hong Yoon

We present a novel adaptive machine-learning based approach for reconstructing three-dimensional (3D) crystals from coherent diffraction imaging (CDI). We represent the crystals using spherical harmonics (SH) and generate corresponding…

Computational Physics · Physics 2020-12-02 Alexander Scheinker , Reeju Pokharel

We demonstrate that simultaneous reconstruction of scattering and absorption of a mesoscopic system using angularly-resolved measurements of scattered light intensity is possible. Image reconstruction is realized based on the algebraic…

Optics · Physics 2011-01-07 Lucia Florescu , John C. Schotland , Vadim A. Markel

Addressing the need for efficient and integrated multiscale crystallographic and defect analyses of advanced materials, this paper presents the implementation of a new multi-configuration detection system, integrating a single…

Instrumentation and Detectors · Physics 2026-05-19 Nohayla El-Khairaoui , Julien Guyon , Nathalie Gey , Luc Morhain , Nabila Maloufi

We introduce a rapid data acquisition and reconstruction method to image the crystalline structure of materials and associated strain and orientations at micrometer resolution using Laue diffraction. Our method relies on scanning a…

Materials Science · Physics 2022-09-15 Doga Gursoy , Dina Sheyfer , Michael Wojcik , Wenjun Liu , Jonathan Z. Tischler

We have developed a method for the linear reconstruction of an image from undersampled, dithered data. The algorithm, known as Variable-Pixel Linear Reconstruction, or informally as Drizzle, preserves photometry and resolution, can weight…

Astrophysics · Physics 2011-08-11 A. S. Fruchter , R. N. Hook

In this report, we applied expectation and maximization (EM) method described by Philips et al [1] to recover two-dimensional (2D) structure from multiple sparse signal images in random orientation. The detailed derivation of EM algorithm…

Data Analysis, Statistics and Probability · Physics 2017-01-12 Yun Zhao

Ultrafast diffraction imaging is a powerful tool to retrieve the geometric structure of gas-phase molecules with combined picometre spatial and attosecond temporal resolution. However, structural retrieval becomes progressively difficult…

Chemical Physics · Physics 2021-10-13 Xinyao Liu , Kasra Amini , Aurelien Sanchez , Blanca Belsa , Tobias Steinle , Jens Biegert

The association of scanning transmission electron microscopy (STEM) and the detection of a diffraction pattern at each probe position (so-called 4D-STEM) represents one of the most promising approaches to analyze structural properties of…

Applied Physics · Physics 2023-01-26 Leonardo Corrêa , Eduardo Ortega , Arturo Ponce , Mônica Cotta , Daniel Ugarte

There is only a handful of scanning techniques that can provide surface topography at nanometre resolution. At the same time, there are no methods that are capable of non-invasive imaging of the three-dimensional surface topography of a…

Instrumentation and Detectors · Physics 2017-03-07 Tatiana Latychevskaia , Wei-Hao Hsu , Wei-Tse Chang , Chun-Yueh Lin , Ing-Shouh Hwang

Active stereo cameras that recover depth from structured light captures have become a cornerstone sensor modality for 3D scene reconstruction and understanding tasks across application domains. Existing active stereo cameras project a…

Computer Vision and Pattern Recognition · Computer Science 2021-05-27 Seung-Hwan Baek , Felix Heide

Methods of three-dimensional deconvolution with a point-spread function as frequently employed in optical microscopy to reconstruct true three-dimensional distribution of objects are extended to holographic reconstructions. Two such schemes…

Optics · Physics 2017-08-09 Tatiana Latychevskaia , Fabian Gehri , Hans-Werner Fink

This paper presents some applications of using recently developed algorithms for smooth-continuous data reconstruction based on the digital-discrete method. The classical discrete method for data reconstruction is based on domain…

Numerical Analysis · Mathematics 2010-03-12 Li Chen

Single particle cryogenic electron microscopy (cryo-EM) is an imaging technique capable of recovering the high-resolution 3-D structure of biological macromolecules from many noisy and randomly oriented projection images. One notable…

Biomolecules · Quantitative Biology 2024-01-30 Andy Zhang , Oscar Mickelin , Joe Kileel , Eric J. Verbeke , Nicholas F. Marshall , Marc Aurèle Gilles , Amit Singer

Material properties strongly depend on the nature and concentration of defects. Characterizing these features may require nano- to atomic-scale resolution to establish structure-property relationships. 4D-STEM, a technique where diffraction…

Materials Science · Physics 2023-05-03 Stephanie M. Ribet , Colin Ophus , Roberto dos Reis , Vinayak P. Dravid

Single Photon Emission Computed Tomography (SPECT) is one of the nuclear medicine imaging modalities used for functional analysis of animal and human organs. Gamma rays emitted from the scanned body are filtered with collimators and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Manu Francis , Muhammed Tarek , Mark Pickering , Murat Tahtali