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We consider the motion of red blood cells and other non-spherical microcapsules dilutely suspended in a simple shear flow. Our analysis indicates that depending on the viscosity, membrane elasticity, geometry and shear rate, the particle…

Soft Condensed Matter · Physics 2015-06-25 J. M. Skotheim , T. W. Secomb

The dynamics of fluid vesicles in simple shear flow is studied using mesoscale simulations of dynamically-triangulated surfaces, as well as a theoretical approach based on two variables, a shape parameter and the inclination angle, which…

Soft Condensed Matter · Physics 2015-06-25 Hiroshi Noguchi , Gerhard Gompper

An analytical theory is developed to describe the dynamics of a closed lipid bilayer membrane (vesicle) freely suspended in a general linear flow. Considering a nearly spherical shape, the solution to the creeping-flow equations is obtained…

Biological Physics · Physics 2009-11-13 Petia M. Vlahovska , Ruben Serral Gracia

Tank-treading, tumbling and trembling are different types of the vesicle behavior in an external flow. We derive a dynamical equation for nearly spherical vesicles enabling to establish a phase diagram of the system predicting the regimes.…

Soft Condensed Matter · Physics 2007-05-25 V. V. Lebedev , K. S. Turitsyn , S. S. Vergeles

An exhaustive description of the dynamics under shear flow of a large number of red blood cells in dilute regime is proposed, which highlights and takes into account the dispersion in cell properties within a given blood sample.…

Biological Physics · Physics 2019-02-11 Christophe Minetti , Vassanti Audemar , Thomas Podgorski , Gwennou Coupier

We study the fully nonlinear, nonlocal dynamics of two-dimensional multicomponent vesicles in a shear flow with matched viscosity of the inner and outer fluids. Using a nonstiff, pseudo-spectral boundary integral method, we investigate…

Soft Condensed Matter · Physics 2016-11-01 Kai Liu , Gary R. Marple , Shuwang Li , Shravan Veerapaneni , John Lowengrub

Vesicles are becoming a quite popular model for the study of red blood cells (RBCs). This is a free boundary problem which is rather difficult to handle theoretically. Quantitative computational approaches constitute also a challenge. In…

Soft Condensed Matter · Physics 2015-05-14 Alexander Farutin , Thierry Biben , Chaouqi Misbah

We report a numerical study addressing the dynamics of compound vesicles confined in a channel under shear flow. The system comprises a smaller vesicle embedded within a larger one and can be used to mimic, for example, leukocytes or…

Soft Condensed Matter · Physics 2025-12-11 A. Lamura

Despite its significance in microfluidics, the effect of confinement on the transition from the tank-treading (steady motion) to the tumbling (unsteady motion) dynamical state of deformable micro-particles has not been studied in detail. In…

Soft Condensed Matter · Physics 2012-07-17 Badr Kaoui , Timm Krüger , Jens Harting

The dynamics of a nucleate cell in shear flow is of great relevance in cancer cells and circulatory tumor cells where they dominate the dynamics of blood. Buoyed by the success of Giant Unilamellar vesicles in explaining the dynamics of…

Soft Condensed Matter · Physics 2018-12-04 Kumari Priti Sinha , Rochish M Thaokar

We review the dynamical behavior of giant fluid vesicles in various types of external hydrodynamic flow. The interplay between stresses arising from membrane elasticity, hydrodynamic flows, and the ever present thermal fluctuations leads to…

Soft Condensed Matter · Physics 2014-05-12 David Abreu , Michael Levant , Victor Steinberg , Udo Seifert

Vesicles under shear flow exhibit various dynamics: tank-treading ($tt$), tumbling ($tb$) and vacillating-breathing ($vb$). A consistent higher order theory reveals a direct bifurcation from $tt$ to $tb$ if $C_a\equiv \tau \dot\gamma $ is…

Soft Condensed Matter · Physics 2009-11-13 Gerrit Danker , Thierry Biben , Thomas Podgorski , Claude Verdier , Chaouqi Misbah

Motivated by the reported peculiar dynamics of a red blood cell in shear flow, we develop an analytical theory for the motion of a nearly--spherical fluid particle enclosed by a visco--elastic incompressible interface in linear flows. The…

Fluid Dynamics · Physics 2010-07-06 Petia M. Vlahovska , Yuan-nan Young , Gerrit Danker , Chaouqi Misbah

The study of vesicles under flow, a model system for red blood cells (RBCs), is an essential step in understanding various intricate dynamics exhibited by RBCs in vivo and in vitro. Quantitative 3D analyses of vesicles under flow are…

Soft Condensed Matter · Physics 2009-12-24 Thierry Biben , Alexander Farutin , Chaouqi Misbah

The dynamics and rheology of suspensions of fluid vesicles or red blood cells is investigated by a combination of molecular dynamics and mesoscale hydrodynamics simulations in two dimensions. The vesicle suspension is confined between two…

Soft Condensed Matter · Physics 2013-05-03 A. Lamura , G. Gompper

The dynamics and rheology of a vesicle confined in a channel under shear flow are studied at finite temperature. The effect of finite temperature on vesicle motion and system viscosity is investigated. A two-dimensional numerical model,…

Soft Condensed Matter · Physics 2022-10-04 A. Lamura

We reveal that under moderate shear stress (of the order of 0.1 Pa) red blood cells present an oscillation of their inclination (swinging) superimposed to the long-observed steady tanktreading (TT) motion. A model based on a fluid ellipsoid…

Biological Physics · Physics 2009-11-13 Manouk Abkarian , Magalie Faivre , Annie Viallat

Blood viscosity decreases with shear stress, a property essential for an efficient perfusion of the vascular tree. Shear-thinning is intimately related to the dynamics and mutual interactions of red blood cells (RBCs), the major…

Via computer simulations, we provide evidence that the shear rate induced red blood cell tumbling-to-tank-treading transition also occurs at quite high volume fractions, where collective effects are important. The transition takes place as…

Soft Condensed Matter · Physics 2013-12-13 Timm Krüger , Markus Gross , Dierk Raabe , Fathollah Varnik

Blood exhibits a heterogeneous nature of hematocrit, velocity, and effective viscosity in microcapillaries. Microvascular bifurcations have a significant influence on the distribution of the blood cells and blood flow behavior. This paper…

Biological Physics · Physics 2016-02-24 Tong Wang , Uwitije Rongin , Zhongwen Xing
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