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Three-color coherent anti-Stokes Raman scattering represents non-degenerate four wave mixing process that includes both a non-resonant and resonant processes, the contributions of which depend on how the molecular vibrational modes are…

Optics · Physics 2020-10-14 Supriya Nagpal , Bryan Semon , Gombojav O. Ariunbold

Single-shot time resolved Coherent Anti-Stokes Raman Scattering (CARS) is presented as a viable method for fast measurements of molecular spectra. The method is based on the short spatial extension of femtosecond pulses and maps time delays…

Optics · Physics 2009-11-13 Yuri Paskover , I. Sh. Averbukh , Yehiam Prior

Second-order nonlinear optical interactions such as sum- and difference-frequency generation are widely used for bioimaging and as selective probes of interfacial environments. However, inefficient nonlinear optical conversion often leads…

Optics · Physics 2015-05-07 Aaron J. Goodman , William A. Tisdale

Coherent anti-Stokes Raman scattering is a widely used imaging technique that provides chemical contrast without the need for labels, making it an extremely valuable tool in physics, chemistry, and biology. In this work, we explore its…

Quantum Physics · Physics 2025-08-05 Giacomo Sorelli , Manuel Gessner , Frank Schlawin

We report a proof-of-concept demonstration of a tunable infrared (IR) optical coherence tomography (OCT) technique with detection of only visible range photons. Our method is based on the nonclassical interference of frequency correlated…

Quantum Physics · Physics 2018-04-09 Anna V. Paterova , Hongzhi Yang , Chengwu An , Dmitry A. Kalashnikov , Leonid A. Krivitsky

Using symmetry arguments we show how optical second harmonic generation (SHG) can be used to detect antiferromagnetism at surfaces and in thin films. Based on the group theoretical analysis of the nonlinear electric susceptibility we…

Condensed Matter · Physics 2007-05-23 A. Daehn , W. Huebner , K. H. Bennemann

We extend image scanning microscopy to second harmonic generation (SHG) by extracting the complex field amplitude of the second-harmonic beam. While the theory behind coherent image scanning microscopy (ISM) is known, an experimental…

Optics · Physics 2022-03-14 Dekel Raanan , Man Suk Song , William A Tisdale , Dan Oron

Optical coherence tomography (OCT) is a high-resolution three-dimensional imaging technique that enables non-destructive measurements of surface and subsurface microstructures. Recent developments of OCT operating in the mid-infrared (MIR)…

Optics · Physics 2020-07-15 Ivan Zorin , Rong Su , Bettina Heise , Bernhard Lendl , Markus Brandstetter

We report stimulated Raman spectroscopy of the G phonon in both single and multi-layer graphene, through Coherent anti-Stokes Raman Scattering (CARS). The signal generated by the third order nonlinearity is dominated by a vibrationally…

Mesoscale and Nanoscale Physics · Physics 2019-09-11 A. Virga , C. Ferrante , G. Batignani , D. De Fazio , A. D. G. Nunn , A. C. Ferrari , G. Cerullo , T. Scopigno

Coherent Anti Stokes Raman Scattering (CARS) offers many advantages for nonlinear bio-imaging, thanks to its sub-cellular spatial resolution and unique chemical specificity. Its working principle requires two incident pulsed laser beams…

We study how coherent scattering of a background gas off an atom (or other matter) interferometer can lead to enhanced signals from phase shifts and contrast loss. We focus on the inclusion of realistic features of atom interferometers such…

High Energy Physics - Phenomenology · Physics 2025-09-18 Clara Murgui , Ryan Plestid

Since its first demonstration in the sixties, coherent anti-Stokes Raman scattering (CARS) has become a powerful spectroscopic sensing tool with broad applications in biology and chemistry. However, it is a complex nonlinear optical process…

Optics · Physics 2020-07-15 Gombojav O. Ariunbold , Supriya Nagpal , Bryan Semon

Coherent anti-Stokes Raman scattering (CARS) microscopy is combined with second harmonic generation (SHG) technique in order to follow the early stage of stem cell differentiation within a 3D scaffold. CARS microscopy can detect lipid…

Biological Physics · Physics 2015-10-28 Leonardo Mortati , Carla Divieto , Maria Paola Sassi

Coherent anti-Stokes Raman scattering (CARS) spectroscopy with time-delayed ultrashort pulses and a single-pixel photodetector has shown great potential for spectroscopic imaging and transient studies in chemistry and biological research.…

Optics · Physics 2023-12-05 Tianjian Lv , Bing Han , Ming Yan , Zhaoyang Wen , Kun Huang , Kangwen Yang , Heping Zeng

We developed a new endogenous approach to reveal subcellular metabolic contrast in fresh ex vivo tissues taking advantage of the time dependence of the full field optical coherence tomography interferometric signals. This method reveals…

Medical Physics · Physics 2016-01-07 Clement Apelian , Fabrice Harms , Olivier Thouvenin , A. Claude Boccara

We propose a new technique, called quantum optical coherence tomography (QOCT), for carrying out tomographic measurements with dispersion-cancelled resolution. The technique can also be used to extract the frequency-dependent refractive…

Early theoretical works on coherent anti-Stokes Raman scattering in optically active medium consider only heterodyne signal and subsequently, fourth- and fifth-rank tensor averages have been used. In this work, we presented a full signal…

Quantum Physics · Physics 2019-01-03 Tuguldur Kh. Begzjav , Marlan O. Scully , Girish S. Agarwal

Surface-enhanced coherent anti-Stokes Raman scattering (SE-CARS) takes advantage of surface plasmon resonances supported on metallic nanostructures to amplify the coherent Raman response of target molecules. While these metallic antennas…

Optics · Physics 2022-09-07 Shamsul Abedin , Yong Li , Abid Anjum Sifat , Khokan Roy , Eric Olaf Potma

The emergence of label-free microscopy techniques has significantly improved our ability to precisely characterize biochemical targets, enabling non-invasive visualization of cellular organelles and tissue organization. Each label-free…

Optics · Physics 2024-05-08 Lang Wang , Maxine Xii , Ali Pezeshki , Randy Bartels

Optical Coherence Tomography(OCT) is a non-invasive technique capturing cross-sectional area of the retina in micro-meter resolutions. It has been widely used as a auxiliary imaging reference to detect eye-related pathology and predict…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Shuo Chen , Da Ma , Sieun Lee , Timothy T. L. Yu , Gavin Xu , Donghuan Lu , Karteek Popuri , Myeong Jin Ju , Marinko V. Sarunic , Mirza Faisal Beg