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Monte Carlo simulation is an essential tool in emission tomography that can assist in the design of new medical imaging devices, the optimization of acquisition protocols, and the development or assessment of image reconstruction algorithms…

Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation…

The Resistive Plate Chambers (RPC) are low-cost charged-particle detectors with good timing resolution and potentially good spatial resolution. Using RPC as gamma detector provides an opportunity for application in positron emission…

Instrumentation and Detectors · Physics 2014-02-20 Zhou Weizheng , Shao Ming , Li Cheng , Chen Hongfang , Sun Yongjie , Chen Tianxiang

The Generic Geant4 Simulation (GGS) is a package designed to speed-up the realization and deployment of Monte Carlo simulation software based on Geant4, for small- and medium-sized high-energy experiments. For many common use cases, the…

Data Analysis, Statistics and Probability · Physics 2021-04-22 Nicola Mori

The imaging performance of a high-resolution preclinical microPET system employing liquid xenon as the gamma ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection…

Medical Physics · Physics 2012-03-23 A. Miceli , J. Glister , A. Andreyev , D. Bryman , L. Kurchaninov , P. Lu , A. Muennich , F. Retiere , V. Sossi

Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development…

The low cost and high resolution gas-based Multi-gap Resistive Plate Chamber (MRPC) opens a new possibility to find an efficient alternative detector for Time of Flight (TOF) based Positron Emission Tomography, where the sensitivity of the…

Instrumentation and Detectors · Physics 2011-06-30 A. Banerjee , S. Chattopadhyay

The full-energy-peak efficiency of HPGe detectors at $\gamma$-ray energies around 10 MeV is not easily accessible with experimental methods. Monte-Carlo simulations with Geant4 can provide these efficiencies. G4Horus is a ready-to-use…

Instrumentation and Detectors · Physics 2020-06-15 Jan Mayer , Elena Hoemann , Markus Müllenmeister , Philipp Scholz , Andreas Zilges

Monte Carlo simulations are increasingly used in scintigraphic imaging to model imaging systems and to develop and assess tomographic reconstruction algorithms and correction methods for improved image quantitation. GATE (GEANT 4…

Instrumentation and Detectors · Physics 2009-11-10 D. Lazaro , I. Buvat , G. Loudos , D. Strul , G. Santin , N. Giokaris , D. Donnarieix , L. Maigne , V. Spanoudaki , S. Styliaris , S. Staelens , V. Breton

This work is the second part of a simulation study investigating the processing of densely packed and moving granular assemblies by positron emission particle tracking (PEPT). Since medical PET scanners commonly used for PEPT are very…

The measurement of the time of flight of the two 511 keV gammas recorded in coincidence in a PET scanner provides an effective way of reducing the random background and therefore increases the scanner sensitivity, provided that the…

Instrumentation and Detectors · Physics 2016-10-12 J. J Gomez-Cadenas , J. M. Benlloch-Rodríguez , P. Ferrario , F. Monrabal , J. Rodríguez , J. F. Toledo

PETALO (Positron Emission Tof Apparatus with Liquid xenOn) is a novel concept for positron emission tomography scanners, which uses liquid xenon as a scintillation medium and silicon photomultipliers as a readout. The large scintillation…

Instrumentation and Detectors · Physics 2022-02-02 Paola Ferrario

New detector approaches in Positron Emission Tomography imaging will play an important role in reducing costs, lowering administered radiation doses, and improving overall performance. PETALO employs liquid xenon as the active scintillating…

We have used the TOPAS Geant4-based package to create a parametric simulation of a new TOF-PET scanner design based on a low atomic number scintillator. TOPAS was extended to provide complete information on individual particle position,…

Medical Physics · Physics 2023-10-03 Kepler Domurat-Sousa , Cameron Poe

The response of the X and Gamma Imaging Spectrometer (XGIS) instrument onboard the Transient High Energy Sky and Early Universe Surveyor (THESEUS) mission, selected by ESA for an assessment phase in the framework of the Cosmic Vision M5…

Instrumentation and Methods for Astrophysics · Physics 2021-02-18 Riccardo Campana , Fabio Fuschino , Claudio Labanti , Sandro Mereghetti , Enrico Virgilli , Valentina Fioretti , Mauro Orlandini , John B. Stephen , Lorenzo Amati

The rapid development of X-ray astronomy has been made possible by widely deploying X-ray focusing telescopes on board many X-ray satellites. Geant4 is a very powerful toolkit for Monte Carlo simulations and has remarkable abilities to…

Instrumentation and Methods for Astrophysics · Physics 2017-03-29 Donghua Zhao , Chen Zhang , Weimin Yuan , Shuangnan Zhang , Richard Willingale , Zhixing Ling

The Miniaturized Detector for Application in Space (MIDAS) is a compact device with dimensions 5 x 5 x 1 cm3 which combines position sensitive Si detectors and a fast neutrons spectrometer. MIDAS is developed with purpose to act as a linear…

Instrumentation and Detectors · Physics 2022-02-22 K. Karafasoulis , C. Papadimitropoulos , C. Potiriadis , C. P. Lambropoulos

Monte Carlo Simulation (MCS) is a state-of-the-art technique in designing sophisticated apparatus for various applications in science and technology. We adopted MCS based on GEANT (GEometry ANd Tracking) in order to design a simple…

Medical Physics · Physics 2010-06-30 Nagendra Nath Mondal

Monte Carlo simulations are powerful tools for understanding the effects of radiation interactions within detector devices allowing not only to evaluate typical estimates for experimental measurements and to serve as means for designing…

Instrumentation and Detectors · Physics 2016-02-09 F. Marinho , K. Akiba

A detector using liquid Xenon (LXe) in the scintillation mode is studied for Positron Emission Tomography (PET) of small animals. Its specific design aims at taking full advantage of the Liquid Xenon scintillation properties. This paper…

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