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The precise details of how myosin-V coordinates the biochemical reactions and mechanical motions of its two head elements to engineer effective processive molecular motion along actin filaments remain unresolved. We compare a quantitative…

Biomolecules · Quantitative Biology 2009-11-13 K. I. Skau , R. B. Hoyle , M. S Turner

The motion of a rigid body in a quadratic potential is an important example of an integrable Hamiltonian system on a dual to a semidirect product Lie algebra so(n) x Symm(n). We give a Lagrangian derivation of the corresponding equations of…

solv-int · Physics 2007-05-23 Yuri B. Suris

Synthetic microswimmers offer models for cell motility and their tunability makes them promising candidates for biomedical applications. Here we measure the acoustic propulsion of bimetallic micro-rods that, when trapped at the nodal plane…

Soft Condensed Matter · Physics 2021-09-20 Jeffrey McNeill , Nathan Sinai , Justin Wang , Vincent Oliver , Eric Lauga , Francois Nadal , Thomas E. Mallouk

A simple model for solid friction is analyzed. It is based on tangential springs representing interlocked asperities of the surfaces in contact. Each spring is given a maximal strain according to a probability distribution. At their maximal…

Materials Science · Physics 2007-05-23 Z. Farkas , S. R. Dahmen , D. E. Wolf

Mechanically induced folding of passive cross-linkers is a fundamental biological phenomenon. A typical example is a conformational change in myosin II responsible for the power-stroke in skeletal muscles. In this paper we present an…

Biological Physics · Physics 2017-09-14 Matthieu Caruel , Jean-Marc Allain , Lev Truskinovsky

With materials of anisotropic electrical conductivity, it is possible to generate a dynamo with a simple velocity field, of the type precluded by Cowling's theorems with isotropic materials. Following a previous study by Ruderman and…

Geophysics · Physics 2020-04-28 Thierry Alboussiere , Kamel Drif , Franck Plunian

The mechanical properties of actin filaments are essential to their biological functions. Here, we introduce a highly coarse-grained model of actin filaments that preserves helicity and chirality while enabling mesoscale simulations. The…

Biological Physics · Physics 2026-01-01 Amir Khosravanizadeh , François Nédélec , Serge Dmitrieff

We study the motion of a particle sliding under the action of an external field on a stochastically fluctuating one-dimensional Edwards-Wilkinson surface. Numerical simulations using the single-step model shows that the mean-square…

Statistical Mechanics · Physics 2009-11-10 Manoj Gopalakrishnan

Skeletal muscle modeling has a vital role in movement studies and the development of therapeutic approaches. In the current study, a Huxley-based model for skeletal muscle is proposed, which demonstrates the impact of impairments in muscle…

Medical Physics · Physics 2023-09-07 Fatemeh Jalali , Mohammad Ali Nazari , Arash Bahrami , Pascal Perrier , Yohan Payan

This paper presents a novel framework to realize proprioception and closed-loop control for soft manipulators. Deformations with large elongation and large bending can be precisely predicted using geometry-based sensor signals obtained from…

Robotics · Computer Science 2023-09-26 Yinan Meng , Guoxin Fang , Jiong Yang , Yuhu Guo , Charlie C. L. Wang

Fluid-based locomotion at low Reynolds number is subject to the constraints of the scallop theorem, which dictate that body kinematics identical under a time-reversal symmetry (in particular, those with a single degree of freedom) cannot…

Biological Physics · Physics 2013-03-13 Gregory L. Wagner , Eric Lauga

Molecular machines are stochastic systems that catalyze the energetic processes keeping living cells alive and structured. Inspired by the examples of F1-ATP synthase and the bacterial flagellum, we present a minimal model of an externally…

Statistical Mechanics · Physics 2020-03-18 Alexandra K. S. Kasper , David A. Sivak

A new approach is developed to integrate numerically the equations of motion for systems of interacting rigid polyatomic molecules. With the aid of a leapfrog framework, we directly involve principal angular velocities into the integration,…

Computational Physics · Physics 2007-05-23 Igor P. Omelyan

We study in detail the recent suggestions by Tshiprut et al. [Phys. Rev. Lett. 95, 016101 (2005)] to tune tribological properties at the nanoscale by subjecting a substrate to periodic mechanical oscillations. We show that both in…

Mesoscale and Nanoscale Physics · Physics 2011-06-14 Roberto Guerra , Andrea Vanossi , Michael Urbakh

When implementing a non-continuous controller for a cyber-physical system, it may happen that the evolution of the closed-loop system is not anymore piecewise differentiable along the trajectory, mainly due to conditional statements inside…

Robotics · Computer Science 2021-01-15 Luc Jaulin , Benoît Desrochers

A new model for the numerical simulation of a rigid body moving in a viscous fluid flow using FEM is presented. One of the most interesting features of this approach is the small computational effort required to solve the motion of the…

Fluid Dynamics · Physics 2020-12-17 M. I. Herreros , S. Ligüérzana

Muscle contraction, both in skeletal and cardiac tissue, is driven by sarcomeres, the microscopic units inside muscle cells where thick myosin and thin actin filaments slide past each other. During contraction and relaxation, the…

Fluid Dynamics · Physics 2025-03-19 John Severn , Thomas Vacus , Eric Lauga

We designed a very simple asymmetric rolling spool and we studied it experimentally, in the librational regime, by using a video camera and video analysis software. Comparison of experimental results and theoretical analysis allows…

Physics Education · Physics 2014-10-24 P. Onorato , M. Malgieri , P. Mascheretti , A. De Ambrosis

In the first part of the article using a direct calculation two-dimensional motion of a particle sliding on an inclined plane is investigated for general values of friction coefficient ($\mu$). A parametric equation for the trajectory of…

Classical Physics · Physics 2011-06-14 Cina Aghamohammadi , Amir Aghamohammadi

Like the solar cycle, stellar activity cycles are also irregular. Observations reveal that rapidly rotating (young) Sun-like stars exhibit a high level of activity with no Maunder-like grand minima and rarely display smooth regular activity…

Solar and Stellar Astrophysics · Physics 2023-05-10 Vindya Vashishth , Bidya Binay Karak , Leonid Kitchatinov