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Biomedical and biochemical processes in paper-based microfluidic devices often deal with mixing of two analytes to perform important functions. Uniform mixing of analytes in paper matrix is a challenging proposition, often necessitating…

Multivalent particles have the ability to form multiple bonds to a substrate. Hence, a multivalent interaction can be strong, even if the individual bonds are weak. However, much more interestingly, multivalency greatly increases the…

Soft Condensed Matter · Physics 2017-04-04 Tine Curk , Jure Dobnikar , Daan Frenkel

Using a simplified microstructural picture we show that interactions between thermosenstive microgel particles can be described by a polymer brush like corona decorating the dense core. The softness of the potential is set by the relative…

Soft Condensed Matter · Physics 2010-03-29 Frank Scheffold , Pedro Diaz-Leyva , Mathias Reufer , Nasser Ben Braham , Iseult Lynch , James L. Harden

Quantifying the outcomes of cells collisions is a crucial step in building the foundations of a kinetic theory of living matter. Here, we develop a mechanical theory of such collisions by first representing individual cells as extended…

Biological Physics · Physics 2019-12-11 Pierre Recho , Thibaut Putelat , Lev Truskinovsky

Small scale contact between a soft, liquid-coated layer and a stiff surface is common in many situations, from synovial fluid on articular cartilage to adhesives in humid environments. Moreover, many model studies on soft adhesive contacts…

Soft Condensed Matter · Physics 2020-10-01 Justin D. Glover , Jonathan T. Pham

The migratory dynamics of cells in physiological processes, ranging from wound healing to cancer metastasis, rely on contact-mediated cell-cell interactions. These interactions play a key role in shaping the stochastic trajectories of…

In this paper we propose a solution for transmitting digital information within the cardiocirculatory system. In particular, we make use of a channel delivering burst of molecules, emitted by mobile transmitters, which diffuse in the blood…

Networking and Internet Architecture · Computer Science 2013-09-30 Luca Felicetti , Mauro Femminella , Gianluca Reali

This review provides an introduction to the essential physics of soft adhesion, including the thermodynamics of adhesion and wetting, the mechanics of contact with deformable materials, and the material properties that most affect…

Soft Condensed Matter · Physics 2026-03-23 Katharine E. Jensen , Chelsea S. Davis

We study a physical model for the interaction between general inclusions bound to fluid membranes that possess finite tension, as well as the usual bending rigidity. We are motivated by an interest in proteins bound to cell membranes that…

Soft Condensed Matter · Physics 2009-11-10 A. R. Evans , M. S. Turner , P. Sens

Phase separation, crucial for spatially segregating biomolecules in cells, is well-understood in the simple case of a few components with pairwise interactions. Yet, biological cells challenge the simple picture in at least two ways: First,…

Soft Condensed Matter · Physics 2024-03-12 Chengjie Luo , Yicheng Qiang , David Zwicker

Molecular adhesion plays a central role in many biological systems, yet existing methods to quantify adhesive strength often struggle to bridge the gap between single-molecule resolution and biologically relevant environments. Here, we…

Being motivated by the delivery of drugs and vaccines through subcutaneous (SC) injection in human bodies, a theoretical investigation is performed using a two-dimensional mathematical model in the cartesian coordinate. In general, a large…

Fluid Dynamics · Physics 2023-06-08 Abdush Salam Pramanik , Bibaswan Dey , Timir Karmakar , Kalyan Saha

Microfluidic channels are integral to biomedical technology and process engineering, offering versatility in handling fluids with complex properties, often a combination of viscous and elastic attributes. Despite significant advancements in…

Soft Condensed Matter · Physics 2025-09-29 Sampad Laha , Siddhartha Mukherjee , Suman Chakraborty

The behaviour and fate of tissue cells is controlled by the rigidity and geometry of their adhesive environment, possibly through forces localized to sites of adhesion. We introduce a mechanical model that predicts cellular force…

Cell Behavior · Quantitative Biology 2009-07-24 Ilka B. Bischofs , Sebastian S. Schmidt , Ulrich S. Schwarz

The electrostatic interaction between pairs of spherical or macroscopically long, parallel cylindrical colloids trapped at fluid interfaces is studied theoretically for the case of small inter-particle separations. Starting from the…

Soft Condensed Matter · Physics 2018-11-30 Arghya Majee , Markus Bier , S. Dietrich

Microrheology, the study of fluids on micron length-scales, promises to reveal insights into cellular biology, including mechanical biomarkers of disease and the interplay between biomechanics and cellular function. Here a…

Tunable metasurfaces are ultra-thin, artificial electromagnetic components that provide engineered and externally adjustable functionalities. The programmable metasurface, the HyperSurFace, concept consists in integrating controllers within…

Microscale fluid flows generated by ensembles of beating eukaryotic flagella are crucial to fundamental processes such as development, motility and sensing. Despite significant experimental and theoretical progress, the underlying physical…

Soft Condensed Matter · Physics 2014-03-11 Douglas R. Brumley , Kirsty Y. Wan , Marco Polin , Raymond E. Goldstein

There are three regimes of cell membrane interaction with glass - Tight and loose adhesion, separated by repulsion. Explicitly including hydration, this paper evaluates the pressure between the surfaces as functions of distance for…

Soft Condensed Matter · Physics 2021-03-10 Richard W. Clarke

Various microfluidic systems, such as chemical and biological lab-on-a-chip devices, involve motion of multiple droplets within an immersing fluid in shallow micro-channels. Modeling the dynamics of such systems requires calculation of the…

Fluid Dynamics · Physics 2016-08-24 Itai Sarig , Yuli Starosvetsky , Amir D. Gat
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