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A system with two correlated Gaussian white noises is analysed. This system can describe both stochastic localization and long tails in the stationary distribution. Correlations between the noises can lead to a nonmonotonic behaviour of the…

Statistical Mechanics · Physics 2015-06-25 P. F. Gora

It has been generally recognized that stochasticity can play an important role in the information processing accomplished by reaction networks in biological cells. Most treatments of that stochasticity employ Gaussian noise even though it…

Molecular Networks · Quantitative Biology 2015-05-30 Neda Bostani , David A. Kessler , Nadav M. Shnerb , Wouter-Jan Rappel , Herbert Levine

This paper is devoted to exploring the effects of non-Gaussian fluctuations on dynamical evolution of a tumor growth model with immunization, subject to non-Gaussian {\alpha}-stable type L\'evy noise. The corresponding deterministic model…

Dynamical Systems · Mathematics 2012-07-26 Mengli Hao , Ting Gao , Jinqiao Duan , Wei Xu

The uncontrolled proliferation of cancer cells and their interaction with healthy tissue poses a major challenge in oncology. This manuscript develops and analyzes mathematical models that describe tumor response to radiotherapy by…

In a previous work, we presented a model that integrates cancer cell differentiation and immunotherapy, analysing a particular therapy against cancer stem cells by cytotoxic cell vaccines. As every biological system is exposed to random…

Biological Physics · Physics 2022-12-14 Marcela Reale , David Margarit , Ariel Scagliotti , Lilia Romanelli

We consider the decision making by mammalian cells, looking them as dynamic systems with rhythms. We calculate the effective dimension of the cell division model of the healthy mammalian cells consistent with the data: it is described via a…

Cell Behavior · Quantitative Biology 2015-12-18 David B. Saakian

We study a spatially inhomogeneous model of cancer growth based on Michaelis--Menten kinetics, subjected to additive Gaussian noise and multiplicative dichotomous noise. In presence of the latter, we can observe a transition between two…

Cell Behavior · Quantitative Biology 2007-05-23 Anna Ochab-Marcinek

In this paper, we examine the effects of correlated Gaussian noise on a two-dimensional neuronal network that is locally modeled by the Rulkov map. More precisely, we study the effects of the noise correlation on the variations of the mean…

Disordered Systems and Neural Networks · Physics 2010-09-23 Xiaojuan Sun , Matjaz Perc , Qishao Lu , Jürgen Kurths

A linear transmitter with correlated Gaussian white additive and multiplicative noises and a periodic signal coupled either additively or multiplicatively is considered. The correlations have a weak destructive effect in case of the…

Statistical Mechanics · Physics 2007-05-23 P. F. Gora

We study a Langevin equation derived from the Michaelis-Menten (MM) phenomenological scheme for catalysis accompanying a spontaneous replication of molecules, which may serve as a simple model of cell-mediated immune surveillance against…

Populations and Evolution · Quantitative Biology 2008-08-29 A. Ochab-Marcinek , A. Fiasconaro , E. Gudowska-Nowak , B. Spagnolo

Effects of non-Gaussian $\alpha-$stable L\'evy noise on the Gompertz tumor growth model are quantified by considering the mean exit time and escape probability of the cancer cell density from inside a safe or benign domain. The mean exit…

Dynamical Systems · Mathematics 2016-12-21 Jian Ren , Chujin Li , Ting Gao , Xingye Kan , Jinqiao Duan

We study the joint effect of thermal bath fluctuations and an external noise tuning activity of cytotoxic cells on the triggered immune response in a growing cancerous tissue. The immune response is assumed to be primarily mediated by…

Populations and Evolution · Quantitative Biology 2015-06-26 Anna Ochab-Marcinek , Ewa Gudowska-Nowak

Models of population growth and extinction are an increasingly popular subject of study. However, consequences of stochasticity and noise in shaping distributions and outcomes are not sufficiently explored. Here we consider a distributed…

Statistical Mechanics · Physics 2020-11-11 Bertrand Ottino-Löffler , Mehran Kardar

Linear dynamical systems, driven by a non-white noise which has the Levy distribution, are analysed. Noise is modelled by a specific stochastic process which is defined by the Langevin equation with a linear force and the Levy distributed…

Statistical Mechanics · Physics 2011-01-26 Tomasz Srokowski

Ordinary differential equation models are used to describe dynamic processes across biology. To perform likelihood-based parameter inference on these models, it is necessary to specify a statistical process representing the contribution of…

We study the role of the noise in the dynamics of two competing species. We consider generalized Lotka-Volterra equations in the presence of a multiplicative noise, which models the interaction between the species and the environment. The…

Statistical Mechanics · Physics 2015-06-24 D. Valenti , A. Fiasconaro , B. Spagnolo

We investigate a stochastic version of a simple enzymatic reaction which follows the generic Michaelis-Menten kinetics. At sufficiently high concentrations of reacting species, the molecular fluctuations can be approximated as a realization…

Populations and Evolution · Quantitative Biology 2009-11-13 A. Fiasconaro , A. Ochab-Marcinek , B. Spagnolo , E. Gudowska-Nowak

I calculate the noise in the measured correlation functions and spectra of digitized, noiselike signals. In the spectral domain, the signals are drawn from a Gaussian distribution with variance that depends on frequency. Nearly all…

Astrophysics · Physics 2007-05-23 C. R. Gwinn

In this paper, we formulate a stochastic logistic fish growth model driven by both white noise and non-Gaussian noise. We focus our study on the mean time to extinction, escape probability to measure the noise-induced extinction probability…

Probability · Mathematics 2020-09-03 A. Tesfay , D. Tesfay , A. Khalaf , J. Brannan

This paper investigates dynamic behaviors of the tumor-immune system perturbed by environmental noise. The model describes the response of the cytotoxic T lymphocyte (CTL) to the growth of an immunogenic tumour. The main methods are…

Probability · Mathematics 2019-02-06 Xiaoyue Li , Guoting Song , Yang Xia , Chenggui Yuan