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To understand sensory coding, we must ask not only how much information neurons encode, but also what that information is about. This requires decomposing mutual information into contributions from individual stimuli and stimulus features:…

Neurons and Cognition · Quantitative Biology 2025-10-23 Steeve Laquitaine , Simone Azeglio , Carlo Paris , Ulisse Ferrari , Matthew Chalk

Neuroscientists have enjoyed much success in understanding brain functions by constructing brain connectivity networks using data collected under highly controlled experimental settings. However, these experimental settings bear little…

Machine Learning · Statistics 2019-06-24 Kean Ming Tan , Junwei Lu , Tong Zhang , Han Liu

As experiments advance to record from tens of thousands of neurons, statistical physics provides a framework for understanding how collective activity emerges from networks of fine-scale correlations. While modeling these populations is…

Biological Physics · Physics 2024-12-25 David P. Carcamo , Christopher W. Lynn

The cognitive framework of conceptual spaces proposes to represent concepts as regions in psychological similarity spaces. These similarity spaces are typically obtained through multidimensional scaling (MDS), which converts human…

Machine Learning · Computer Science 2020-04-08 Lucas Bechberger , Kai-Uwe Kühnberger

Behavior results from the integration of ongoing sensory signals and contextual information in various forms, such as past experience, expectations, current goals, etc. Thus, the response to a specific stimulus, say the ringing of a…

Neurons and Cognition · Quantitative Biology 2007-05-23 Emilio Salinas

The activity of ensembles of simultaneously recorded neurons can be represented as a set of points in the space of firing rates. Even though the dimension of this space is equal to the ensemble size, neural activity can be effectively…

Neurons and Cognition · Quantitative Biology 2016-03-17 Luca Mazzucato , Alfredo Fontanini , Giancarlo La Camera

A single neuron is categorized as"multisensory" if there is a statistically significant difference between the response evoked by an audio-visual stimulus combination and that evoked by the most effective of its components individually.…

Neurons and Cognition · Quantitative Biology 2016-08-09 Hans Colonius , Adele Diederich

Redundancies and correlations in the responses of sensory neurons seem to waste neural resources but can carry cues about structured stimuli and may help the brain to correct for response errors. To assess how the retina negotiates this…

Neurons and Cognition · Quantitative Biology 2014-03-05 K. D. Simmons , J. S. Prentice , G. Tkacik , J. Homann , H. K. Yee , S. E. Palmer , P. C. Nelson , V. Balasubramanian

In this work, we study non-asymptotic bounds on correlation between two time realizations of stable linear systems with isotropic Gaussian noise. Consequently, via sampling from a sub-trajectory and using \emph{Talagrands'} inequality, we…

Machine Learning · Statistics 2023-04-05 Muhammad Abdullah Naeem

We propose an extensive simulation study to compare some variable selection procedures in a high-dimensional framework. Assuming that the relationship between the actives variables and the response variable is linear, the high-dimensional…

Applications · Statistics 2025-03-21 Perrine Lacroix , Mélina Gallopin , Marie-Laure Martin

Understanding how neural dynamics shape cognitive experiences remains a central challenge in neuroscience and psychiatry. Here, we present a novel framework leveraging state-to-output controllability from dynamical systems theory to model…

The traditional view of neural computation in the cerebral cortex holds that sensory neurons are specialized, i.e., selective for certain dimensions of sensory stimuli. This view was challenged by evidence of contextual interactions between…

Neurons and Cognition · Quantitative Biology 2022-04-26 Sergei Gepshtein , Ambarish Pawar , Sunwoo Kwon , Sergey Savel'ev , Thomas D. Albright

Correlations in sensory neural networks have both extrinsic and intrinsic origins. Extrinsic or stimulus correlations arise from shared inputs to the network, and thus depend strongly on the stimulus ensemble. Intrinsic or noise…

Neurons and Cognition · Quantitative Biology 2018-11-05 Ulisse Ferrari , Stephane Deny , Matthew Chalk , Gasper Tkacik , Olivier Marre , Thierry Mora

Cortical neurons whose activity is recorded in behavioral experiments has been classified into several types such as stimulus-related neurons, delay-period neurons, and reward-related neurons. Moreover, the population activity of neurons…

Neurons and Cognition · Quantitative Biology 2018-11-27 Takuma Tanaka

Understanding how neural population responses represent sensory information is a central problem in systems neuroscience. One approach is to define a representational geometry on stimulus space in which distances reflect how reliably…

Neurons and Cognition · Quantitative Biology 2026-05-08 Simone Azeglio , Steeve Laquitaine , Ulisse Ferrari , Matthew Chalk

Biological and artificial neural systems form high-dimensional neural representations that underpin their computational capabilities. Methods for quantifying geometric similarity in neural representations have become a popular tool for…

Neurons and Cognition · Quantitative Biology 2024-12-20 Amin Nejatbakhsh , Victor Geadah , Alex H. Williams , David Lipshutz

Parallel recordings of neural spike counts have revealed the existence of context-dependent noise correlations in neural populations. Theories of population coding have also shown that such correlations can impact the information encoded by…

Machine Learning · Computer Science 2025-07-30 Sacha Sokoloski , Ruben Coen-Cagli

The cognitive framework of conceptual spaces bridges the gap between symbolic and subsymbolic AI by proposing an intermediate conceptual layer where knowledge is represented geometrically. There are two main approaches for obtaining the…

Machine Learning · Computer Science 2019-08-08 Lucas Bechberger , Elektra Kypridemou

Psychometric functions typically characterize binary sensory decisions along a single stimulus dimension. However, real-life sensory tasks vary along a greater variety of dimensions (e.g. color, contrast and luminance for visual stimuli).…

Neurons and Cognition · Quantitative Biology 2023-02-03 Stephen Keeley , Benjamin Letham , Chase Tymms , Craig Sanders , Michael Shvartsman

Information flow provides a natural measure for the causal interaction between dynamical events. This study extends our previous rigorous formalism of componentwise information flow to the bulk information flow between two complex…

Neurons and Cognition · Quantitative Biology 2021-12-30 X. San Liang