Related papers: Red herrings and rotten fish
Natural selection has shaped the evolution of cells and multi-cellular organisms such that social cooperation can often be preferred over an individualistic approach to metabolic regulation. This paper extends a framework for dynamic…
In this paper, we look at four generalizations of the one dimensional Aubry-Andre-Harper (AAH) model which possess mobility edges. We map out a phase diagram in terms of population imbalance, and look at the system size dependence of the…
Most physical and other natural systems are complex entities composed of a large number of interacting individual elements. It is a surprising fact that they often obey the so-called scaling laws relating an observable quantity with a…
Individual resource intake rates are known to depend on both individual body size and resource availability. Here, we have developed a model to integrate these two drivers, accounting explicitly for the scaling of perceived resource…
Recent experimental results from the LHCb, BaBar and Belle collaborations on the semitauonic decays of $B$ meson, $\bar{B}\rightarrow D^{(\ast)}\tau \bar{\nu}$, showing a significant deviation from the Standard Model (SM), hint towards a…
Despite major environmental and genetic differences, microbial metabolic networks are known to generate consistent physiological outcomes across vastly different organisms. This remarkable robustness suggests that, at least in bacteria,…
We design a stochastic individual-based model structured in energy, for single species consuming an external resource, where populations are characterized by a typical energy at birth in $\mathbb{R}^{*}_{+}$. The resource is maintained at a…
Metabolic networks are known to be scale free but the evolutionary origin of this structural property is not clearly understood. One way of studying the dynamical process is to compare the metabolic networks of species that have arisen at…
The metabolic network plays a crucial role in regulating bacterial metabolism and growth, but it is subject to inherent molecular stochasticity. Previous studies have utilized flux balance analysis and the maximum entropy method to predict…
In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the…
In this paper we derive a statistical law of Life. It governs the probability of death, or complementary of survival, of the living organisms. We have deduced such a law coupling the widely used Weibull statistics, developed for describing…
The metabolic activity of microbes has played an essential role in the evolution and persistence of life on Earth. Microbial metabolism plays a primary role in the flow of carbon, nitrogen and other elements through the biosphere on a…
We revisit the modeling of the diauxic growth of a pure microorganism on two distinct sugars which was first described by Monod. Most available models are deterministic and make the assumption that all cells of the microbial ecosystem…
Background: Information processing in the brain requires large amounts of metabolic energy, the spatial distribution of which is highly heterogeneous reflecting complex activity patterns in the mammalian brain. Results: Here, it is found…
Humans, like all organisms, are subject to fundamental biophysical laws. Van Valen predicted that, because of zero-sum dynamics, all populations of all species in a given environment flux the same amount of energy on average. Damuth's…
This is the first report, to our knowledge, on a systematic method for constructing a large scale kinetic metabolic model with incomplete information on kinetic parametersr, and its initial application to the modeling of central metabolism…
Allometry or the quantitative study of the relationship of body size to living organism physiology is an important area of biophysical scaling research. The West-Brown-Enquist (WBE) model of fractal branching in a vascular network explains…
The present view of biological phenomena is based on a biochemical paradigm that development of living organisms is defined by information stored in a molecular form as some genetic code. However, new discoveries indicate that biological…
Weights of edges and nodes on food webs which are available from the empirical data hide much information about energy flows and biomass distributions in ecosystem. We define a set of variables related to weights for each species $i$,…
Ecological modelling of increasingly more complex microbial populations is necessary to reflect the highly functional and diverse behaviour inherent to many systems found in reality. Anaerobic digestion is one such process that has…