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The forest of mutations associated to a multitype branching forest is obtained by merging together all vertices of its clusters and by preserving connections between them. We first show that the forest of mutations of any mulitype branching…

Probability · Mathematics 2015-10-06 Loïc Chaumont , Thi Ngoc Anh Nguyen

In biological systems, expression dynamics that can provide fitted phenotype patterns with respect to a specific function have evolved through mutations. This has been observed in the evolution of proteins for realizing folding dynamics…

Disordered Systems and Neural Networks · Physics 2015-05-13 Ayaka Sakata , Koji Hukushima , Kunihiko Kaneko

We consider an aggregation model for two interacting species. The coupling between the species is via their velocities, that incorporate self- and cross-interactions. Our main interest is categorizing the possible steady states of the…

Analysis of PDEs · Mathematics 2016-12-26 Joep H. M. Evers , Razvan C. Fetecau , Theodore Kolokolnikov

A prediction interval covers a future observation from a random process in repeated sampling, and is typically constructed by identifying a pivotal quantity that is also an ancillary statistic. Analogously, a tolerance interval covers a…

Methodology · Statistics 2022-01-19 Geoffrey S Johnson

Identifying and quantifying the benefits of sex and recombination is a long standing problem in evolutionary theory. In particular, contradictory claims have been made about the existence of a benefit of recombination on high dimensional…

Populations and Evolution · Quantitative Biology 2014-11-11 Stefan Nowak , Johannes Neidhart , Ivan G. Szendro , Joachim Krug

Mechanisms leading to speciation are a major focus in evolutionary biology. In this paper, we present and study a stochastic model of population where individuals, with type a or A, are equivalent from ecological, demographical and spatial…

Populations and Evolution · Quantitative Biology 2017-04-20 Camille Coron , Manon Costa , Hélène Leman , Charline Smadi

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

Multilevel or hierarchical data structures can occur in many areas of research, including economics, psychology, sociology, agriculture, medicine, and public health. Over the last 25 years, there has been increasing interest in developing…

Methodology · Statistics 2018-01-08 Bernet S. Kato , Carel F. W. Peeters

We review models of biological evolution in which the population frequency changes deterministically with time. If the population is self-replicating, although the equations for simple prototypes can be linearised, nonlinear equations arise…

Populations and Evolution · Quantitative Biology 2015-05-27 Kavita Jain , Sarada Seetharaman

The Schelling model of segregation looks to explain the way in which a population of agents or particles of two types may come to organise itself into large homogeneous clusters, and can be seen as a variant of the Ising model in which the…

Discrete Mathematics · Computer Science 2015-08-13 George Barmpalias , Richard Elwes , Andy Lewis-Pye

A microscopic model is developed, within the frame of the theory of quantitative traits, to study both numerically and analytically the combined effect of competition and assortativity on the sympatric speciation process, i.e. speciation in…

Populations and Evolution · Quantitative Biology 2007-05-23 Franco Bagnoli , Carlo Guardiani

Randomly coupled Ising spins constitute the classical model of collective phenomena in disordered systems, with applications covering ferromagnetism, combinatorial optimization, protein folding, stock market dynamics, and social dynamics.…

Disordered Systems and Neural Networks · Physics 2016-08-24 David Dahmen , Hannah Bos , Moritz Helias

The presence of phenomena analogous to phase transition in Statistical Mechanics, has been suggested in the evolution of a polygenic trait under stabilizing selection, mutation and genetic drift. By using numerical simulations of a model…

Populations and Evolution · Quantitative Biology 2017-02-13 Annalisa Fierro , Sergio Cocozza , Antonella Monticelli , Giovanni Scala , Gennaro Miele

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

Probability · Mathematics 2011-01-21 Sylvie Méléard , Sylvie Roelly

Some recent works reveal that there are models of differential equations for the mean and variance of infected individuals that reproduce the SIS epidemic model at some point. This stochastic SIS epidemic model can be interpreted as a…

Populations and Evolution · Quantitative Biology 2020-08-07 Oğul Esen , Eduardo Fernández-Saiz , Cristina Sardón , Marcin Zając

A parameter-dependent model involving nonlinear diffusion for an age-structured population is studied. The parameter measures the intensity of the mortality. A bifurcation approach is used to establish existence of positive equilibrium…

Analysis of PDEs · Mathematics 2010-02-10 Christoph Walker

Phenotypic variation is a hallmark of cellular physiology. Metabolic heterogeneity, in particular, underpins single-cell phenomena such as microbial drug tolerance and growth variability. Much research has focussed on transcriptomic and…

Molecular Networks · Quantitative Biology 2019-01-31 Mona K. Tonn , Philipp Thomas , Mauricio Barahona , Diego A Oyarzún

Spectral statistics of systems that undergo many--body localization transition are studied. An analysis of the gap ratio statistics from the perspective of inter- and intra-sample randomness allows us to pin point differences between…

Disordered Systems and Neural Networks · Physics 2019-03-06 Piotr Sierant , Jakub Zakrzewski

We analyze a nonlocal PDE model describing the dynamics of adaptation of a phenotypically structured population, under the effects of mutation and selection, in a changing environment. Previous studies have analyzed the large-time behavior…

Analysis of PDEs · Mathematics 2020-09-25 Lionel Roques , Florian Patout , Olivier Bonnefon , Guillaume Martin

Exploiting the mathematical curiosity of intransitive dice, we present a simple theoretical model for co-evolution that captures scales ranging from the genome of the individual to the system-wide emergence of species diversity. We study a…

Populations and Evolution · Quantitative Biology 2022-12-02 Julius B. Kirkegaard , Kim Sneppen