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Heritability is a central concept in the long-standing debate about nature versus nurture in biological and social sciences. However, existing notions of heritability are based on strong assumptions and do not use explicit causal models. We…

Applications · Statistics 2026-05-26 Haochen Lei , Jieru Shi , Hongyuan Cao , Qingyuan Zhao

In several domains such as linguistics, molecular biology or social sciences, holistic effects are hardly well-defined by modeling with single units, but more and more studies tend to understand macro structures with the help of meaningful…

Computation and Language · Computer Science 2016-06-02 Nicolas Turenne

Networks are important storage data structures now used to store personal information of individuals around the globe. With the advent of personal genome sequencing, networks are going to be used to store personal genomic sequencing of…

Social and Information Networks · Computer Science 2017-08-22 Komal Batool , Muaz A. Niazi

Random links between otherwise distant nodes can greatly facilitate the propagation of disease or information, provided contagion can be transmitted by a single active node. However we show that when the propagation requires simultaneous…

Physics and Society · Physics 2012-02-10 Damon Centola , Michael W. Macy , Victor M. Eguiluz

In human and animal groups, social interactions often rely on the transmission of information via visual observation of the behavior of others. These visual interactions are governed by the laws of physics and sensory limits. Individuals…

Biological Physics · Physics 2021-06-21 Winnie Poel , Claudia Winklmayr , Pawel Romanczuk

Cancer results from a sequence of genetic and epigenetic changes which lead to a variety of abnormal phenotypes including increased proliferation and survival of somatic cells, and thus, to a selective advantage of pre-cancerous cells. The…

Populations and Evolution · Quantitative Biology 2011-12-05 Erik A. Martens , R. Kostadinov , Carlo C. Maley , Oskar Hallatschek

Modern life largely transmits genetic information from mother to daughter through the duplication of single physically intact molecules that encode information. However, copying an extended molecule requires complex copying machinery and…

Populations and Evolution · Quantitative Biology 2025-09-25 Martin J. Falk , Leon Zhou , Yoshiya J. Matsubara , Kabir Husain , Jack W. Szostak , Arvind Murugan

One of the major goals for astronomy in the next decades is the remote search for biosignatures (i.e.\ the spectroscopic evidence of biological activity) in exoplanets. Here, we adopt a Bayesian statistical framework to discuss the…

Earth and Planetary Astrophysics · Physics 2020-08-19 Amedeo Balbi , Claudio Grimaldi

The mechanical properties of DNA play a critical role in many biological functions. For example, DNA packing in viruses involves confining the viral genome in a volume (the viral capsid) with dimensions that are comparable to the DNA…

From pathogens and computer viruses to genes and memes, contagion models have found widespread utility across the natural and social sciences. Despite their success and breadth of adoption, the approach and structure of these models remain…

Innovation is slowing greatly in the pharmaceutical sector. It is considered here how part of the problem is due to overly limiting intellectual property relations in the sector. On the other hand, computing and software in particular are…

Computers and Society · Computer Science 2011-06-14 Fionn Murtagh

This paper examines the effect of mimicking discontinuous heredity caused by carrying more than one chromosome in some living organisms cells in Evolutionary Multi-Objective Optimization algorithms. In this representation, the phenotype may…

Neural and Evolutionary Computing · Computer Science 2013-03-05 Wesam Elshamy , Hassan M Emara , Ahmed Bahgat

An outstanding open problem is whether collective social phenomena occurring over short timescales can systematically reduce cultural heterogeneity in the long run, and whether offline and online human interactions contribute differently to…

Physics and Society · Physics 2012-01-31 Luca Valori , Francesco Picciolo , Agnes Allansdottir , Diego Garlaschelli

It is high time to openly and without finalism define the dangerous but needed term 'purposeful information', whose quantity is an Eigen information value. Using the term 'biological information' in its stead forces one into an…

Adaptation and Self-Organizing Systems · Physics 2011-12-01 Andrzej Gecow

The phenomenon of gene conservation is an interesting evolutionary problem related to speciation and adaptation. Conserved genes are acted upon in evolution in a way that preserves their function despite other structural and functional…

Genomics · Quantitative Biology 2008-07-23 Bradly J. Alicea , Marcela A. Carvallo-Pinto , Jorge L. M. Rodrigues

Human genomic data carry unique information about an individual and offer unprecedented opportunities for healthcare. The clinical interpretations derived from large genomic datasets can greatly improve healthcare and pave the way for…

Cryptography and Security · Computer Science 2022-09-19 Mohammed Alghazwi , Fatih Turkmen , Joeri van der Velde , Dimka Karastoyanova

Nature (one's genes) and nurture (one's environment) jointly contribute to the formation and evolution of health and human capital over the life cycle. This complex interplay between genes and environment can be estimated and quantified…

The paper is devoted to the consequences of blind random selection of items from different item populations that might be based on completely uncorrelated factors for item inter-correlations and corresponding factor loadings. Based on the…

Applications · Statistics 2021-04-26 André Beauducel , Norbert Hilger

We have presented the basic knowledge on the structure of molecules coding the genetic information, mechanisms of transfer of this information from DNA to proteins and phenomena connected with replication of DNA. In particular, we have…

Genomics · Quantitative Biology 2009-09-30 Dorota Mackiewicz , Stanislaw Cebrat

We point out an analogy between diffractive electron-nucleus scattering events, and realizations of one-dimensional branching random walks selected according to the height of the genealogical tree of the particles near their boundaries.…

High Energy Physics - Phenomenology · Physics 2018-08-24 A. H. Mueller , S. Munier