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Clustering, like covariate selection for classification, is an important step to compress and interpret the data. However, clustering of covariates is often performed independently of the classification step, which can lead to undesirable…

Computation · Statistics 2020-04-08 Daniel Andrade , Kenji Fukumizu , Yuzuru Okajima

Most published studies on the statistical analysis of count data generated by next-generation sequencing technologies have paid surprisingly little attention on cluster analysis. We present a statistical methodology (DGEclust) for…

Quantitative Methods · Quantitative Biology 2015-03-24 Dimitrios V Vavoulis , Margherita Francescatto , Peter Heutink , Julian Gough

Clustering methods are popular for revealing structure in data, particularly in the high-dimensional setting common to contemporary data science. A central statistical question is, "are the clusters really there?" One pioneering method in…

Methodology · Statistics 2023-08-28 Thomas H. Keefe , J. S. Marron

Deep convolutional neural networks (CNNs) have emerged as a new paradigm for Mammogram diagnosis. Contemporary CNN-based computer-aided-diagnosis (CAD) for breast cancer directly extract latent features from input mammogram image and ignore…

Image and Video Processing · Electrical Eng. & Systems 2020-08-13 Heyi Li , Dongdong Chen , William H. Nailon , Mike E. Davies , David Laurenson

In this paper, we introduce a novel and interpretable methodology to cluster subjects suffering from cancer, based on features extracted from their biopsies. Contrary to existing approaches, we propose here to capture complex patterns in…

Quantitative Methods · Quantitative Biology 2020-07-07 Yassine El Ouahidi , Matis Feller , Matthieu Talagas , Bastien Pasdeloup

This work considers clustering nodes of a largely incomplete graph. Under the problem setting, only a small amount of queries about the edges can be made, but the entire graph is not observable. This problem finds applications in…

Machine Learning · Computer Science 2021-10-04 Shahana Ibrahim , Xiao Fu

We consider clustering in group decision making where the opinions are given by pairwise comparison matrices. In particular, the k-medoids model is suggested to classify the matrices since it has a linear programming problem formulation…

Optimization and Control · Mathematics 2025-04-17 Kolos Csaba Ágoston , Sándor Bozóki , László Csató

Clustering is a technique for the analysis of datasets obtained by empirical studies in several disciplines with a major application for biomedical research. Essentially, clustering algorithms are executed by machines aiming at finding…

Quantitative Methods · Quantitative Biology 2024-09-30 Diego Ulisse Pizzagalli , Santiago Fernandez Gonzalez , Rolf Krause

We propose two related unsupervised clustering algorithms which, for input, take data assumed to be sampled from a uniform distribution supported on a metric space $X$, and output a clustering of the data based on the selection of a…

Machine Learning · Computer Science 2022-09-28 Antonio Rieser

Bi-clustering refers to the task of finding sub-matrices (indexed by a group of columns and a group of rows) within a matrix of data such that the elements of each sub-matrix (data and features) are related in a particular way, for…

Machine Learning · Computer Science 2021-11-15 Kaijie Xu

Clustering is widely used in different field such as biology, psychology, and economics. Most traditional clustering algorithms are limited to handling datasets that contain either numeric or categorical attributes. However, datasets with…

Databases · Computer Science 2019-07-03 Trupti M. Kodinariya Dr. Prashant R. Makwana

We present a novel method for testing the hypothesis of equality of two correlation matrices using paired high-dimensional datasets. We consider test statistics based on the average of squares, maximum and sum of exceedances of Fisher…

Methodology · Statistics 2018-04-10 Adria Caballe , Natalia Bochkina , Claus Mayer , Ioannis Papastathopoulos

MicroRNAs play important roles in many biological processes. Their aberrant expression can have oncogenic or tumor suppressor function directly participating to carcinogenesis, malignant transformation, invasiveness and metastasis. Indeed,…

In this work, we developed an efficient approach to compute ensemble averages in systems with pairwise-additive energetic interactions between the entities. Methods involving full enumeration of the configuration space result in exponential…

Biomolecules · Quantitative Biology 2020-10-13 Arun V. Sathanur , Nathan A. Baker

Link discovery is an active field of research to support data integration in the Web of Data. Due to the huge size and number of available data sources, efficient and effective link discovery is a very challenging task. Common pairwise link…

Databases · Computer Science 2017-08-31 Markus Nentwig , Anika Groß , Maximilian Möller , Erhard Rahm

Clustering is the process of finding underlying group structures in data. Although mixture model-based clustering is firmly established in the multivariate case, there is a relative paucity of work on matrix variate distributions and none…

Methodology · Statistics 2018-03-06 Michael P. B. Gallaugher , Paul D. McNicholas

The spectral clustering algorithm is often used as a binary clustering method for unclassified data by applying the principal component analysis. To study theoretical properties of the algorithm, the assumption of conditional…

Statistics Theory · Mathematics 2025-05-27 Kohei Kawamoto , Yuichi Goto , Koji Tsukuda

We intend to identify relationships between cancer cases and pollutant emissions and attempt to understand whether cancer in children is typically located together with some specific chemical combinations or is independent. Co-location…

We introduce a novel profile-based patient clustering model designed for clinical data in healthcare. By utilizing a method grounded on constrained low-rank approximation, our model takes advantage of patients' clinical data and digital…

Machine Learning · Computer Science 2023-08-24 Dongjin Choi , Andy Xiang , Ozgur Ozturk , Deep Shrestha , Barry Drake , Hamid Haidarian , Faizan Javed , Haesun Park

The availability of multi-modality datasets provides a unique opportunity to characterize the same object of interest using multiple viewpoints more comprehensively. In this work, we investigate the use of canonical correlation analysis…

Machine Learning · Computer Science 2024-10-28 Vaishnavi Subramanian , Tanveer Syeda-Mahmood , Minh N. Do