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Dielectrophoretic trapping of six different DNA fragments, sizes varying from the 27 to 8416 bp, has been studied using confocal microscopy. The effect of the DNA length and the size of the constriction between nanoscale fingertip…

The dielectrophoresis method for trapping and attaching nanoscale double-stranded DNA between nanoelectrodes was developed. The method gives a high yield of trapping single or a few molecules only which enables transport measurements at the…

Soft Condensed Matter · Physics 2007-05-23 S. Tuukkanen , A. Kuzyk , J. J. Toppari , V. P. Hytonen , T. Ihalainen , P. Torma

We studied the electrical conductivity of DNA molecules with conducting atomic force microscopy as a function of the chemical nature of the substrate surfaces, the nature of the electrical contact, and the number of DNA molecules (from a…

Materials Science · Physics 2009-11-10 Thomas Heim , Dominique Deresmes , Dominique Vuillaume

Charge migration along DNA molecules has attracted scientific interest for over half a century. Reports on possible high rates of charge transfer between donor and acceptor through the DNA, obtained in the last decade from solution…

Materials Science · Physics 2009-11-10 Danny Porath , Gianaurelio Cuniberti , Rosa Di Felice

We report in detail our experiments on the conduction of $\lambda$ DNA molecules over a wide range of temperature deposited across slits in a few nanometers thick platinum film. These insulating slits were fabricated using focused ion beam…

Mesoscale and Nanoscale Physics · Physics 2015-06-11 A. D. Chepelianskii , D. Klinov , A. Kasumov , S. Guéron , O. Pietrement , S. Lyonnais , H. Bouchiat

We have investigated the conduction over a wide range of temperature of $\lambda$ DNA molecules deposited across slits etched through a few nanometers thick platinum film. The slits are insulating before DNA deposition but contain metallic…

Mesoscale and Nanoscale Physics · Physics 2015-05-20 A. D. Chepelianskii , D. Klinov , A. Kasumov , S. Guéron , O. Pietrement , S. Lyonnais , H. Bouchiat

Debates about conductivity of DNAs have been recently renewed due to contradictory results of direct measurements by use of electrical contacts to molecules. In several works it was discovered that double-stranded (ds)DNAs are conductors:…

Condensed Matter · Physics 2007-05-23 A. Yu. Kasumov , D. V. Klinov

We present a method for controlled connection of gold electrodes with dsDNA molecules (locally on a chip) by utilizing polymerase to elongate single-stranded DNA primers attached to the electrodes. Thiol-modified oligonucleotides are…

Biological Physics · Physics 2011-08-15 Veikko Linko , Jenni Leppiniemi , Boxuan Shen , Einari Niskanen , Vesa P. Hytönen , J. Jussi Toppari

Engineering the synthetic nanopores through lipid bilayer membrane to access the interior of a cell is a long persisting challenge in biotechnology. Here, we demonstrate the stability and dynamics of a tile-based 6-helix DNA nanotube (DNT)…

Soft Condensed Matter · Physics 2017-10-18 Himanshu Joshi , Prabal K. Maiti

We present experimental study of magnetization in $\lambda$-DNA in conjunction with structural measurements. The results show the surprising interplay between the molecular structures and their magnetic property. In the B-DNA state,…

Other Condensed Matter · Physics 2009-11-11 S. Nakamae , M. Cazayous , A. Sacuto , P. Monod , H. Bouchiat

The translocation of a short DNA fragment through a nanopore is addressed when the perforated membrane contains an embedded electrode. Accurate numerical solutions of the coupled Poisson, Nernst-Planck, and Stokes equations for a realistic,…

Soft Condensed Matter · Physics 2017-06-29 Thomas Töws , Peter Reimann

Interest in studying the interaction of small molecules with DNA is caused by the need to develop new, highly effective, and low-toxic drugs for cancer treatment. The strong and highly specific binding of thionine with DNA makes it a…

Biological Physics · Physics 2026-04-29 Evgeniya Usenko , Alexander Glamazda , Vladimir Valeev , Victor Karachevtsev

We study electronic transport in long DNA chains using the tight-binding approach for a ladder-like model of DNA. We find insulating behavior with localizaton lengths xi ~ 25 in units of average base-pair seperation. Furthermore, we observe…

Soft Condensed Matter · Physics 2007-05-23 Antonio Rodriguez , Rudolf A. Roemer , Matthew S. Turner

Motivated by the wide ranging experimental results on the conductivity of DNA, we have investigated extraordinary configurations and chemical environments in which DNA might become a true molecular wire, perticularly from enhanced…

Soft Condensed Matter · Physics 2009-09-29 R. G. Endres , D. L. Cox , R. R. P. Singh

Electrical conductivity of DNA has been a controversial topic since it was first proposed in 1962. Disparities in the experimental results can often be explained by differences of the ambient or experimental conditions. We report the…

Soft Condensed Matter · Physics 2022-06-14 Florian Heimbach , Johann Bohlen , Hans Rabus , Woon Yong Baek , Philip Tinnefeld

The bias-dependent transport properties of short poly(G)-poly(C) A-DNA strands attached to Au electrodes are investigated with first principles electronic transport methods. By using the non- equilibrium Green's function approach combined…

Mesoscale and Nanoscale Physics · Physics 2015-05-19 C. D. Pemmaraju , I. Rungger , X. Chen , A. R. Rocha , S. Sanvito

We studied the electrical conductivity of DNA samples as function of the number of DNA molecules. We showed that the insulating gap (no current at low voltage) increases from ~1-2 V for bundles and large ropes to ~4-7 V for few DNA…

Soft Condensed Matter · Physics 2007-05-23 Thomas Heim , Dominique Deresemes , Dominique Vuillaume

We investigate quantum transport characteristics of a ladder model, which effectively mimics the topology of a double-stranded DNA molecule. We consider the interaction of tunneling charges with a selected internal vibrational degree of…

Soft Condensed Matter · Physics 2007-05-23 R. Gutierrez , S. Mohapatra , H. Cohen , D. Porath , G. Cuniberti

We present a simple and reliable method for making electrical contacts to small organic molecules with thiol endgroups. Nanometer-scale gaps between metallic electrodes have been fabricated by passing a large current through a…

Mesoscale and Nanoscale Physics · Physics 2009-11-10 Subhasis Ghosh , Henny Halimun , Jaewon Choi , Saurabh Lodha , David Janes

We present results of an ultraviolet photoemission spectroscopy study of artificially synthesized poly(dA)-poly(dT) DNA molecules on $p$-type Si substrates. For comparison, we also present the electronic density of states (DOS) calculated…

Soft Condensed Matter · Physics 2007-05-23 Hiroki Wadati , Kozo Okazaki , Yasuhiro Niimi , Atsushi Fujimori , Hitoshi Tabata , Jared Pikus , James P. Lewis
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