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Advances in deep learning models have revolutionized the study of biomolecule systems and their mechanisms. Graph representation learning, in particular, is important for accurately capturing the geometric information of biomolecules at…

Quantitative Methods · Quantitative Biology 2023-04-07 Xinye Xiong , Bingxin Zhou , Yu Guang Wang

A great part of the effort in the study of coarse grained models of transcription networks is directed to the analysis of their dynamical features. In this letter, we consider the \emph{equilibrium} properties of such systems, showing that…

Molecular Networks · Quantitative Biology 2007-05-23 M. Cosentino Lagomarsino , P. Jona , B. Bassetti

This thesis is a compendium of research which brings together ideas from the fields of Complex Networks and Computational Neuroscience to address two questions regarding neural systems: 1) How the activity of neurons, via synaptic changes,…

Neurons and Cognition · Quantitative Biology 2013-02-19 Samuel Johnson

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

Machine Learning · Computer Science 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

Biological Physics · Physics 2015-05-13 Sitabhra Sinha

The pathway is a biological term that refers to a series of interactions between molecules in a cell that causes a certain product or a change in the cell. Pathway analysis is a powerful method for gene expression analysis. Through pathway…

Data Structures and Algorithms · Computer Science 2022-01-11 Lingran Xiao , Yanfei Wang , Shiying Li , Lingxi Chen , Shuaicheng Li

Adaptive networks are a novel class of dynamical networks whose topologies and states coevolve. Many real-world complex systems can be modeled as adaptive networks, including social networks, transportation networks, neural networks and…

Social and Information Networks · Computer Science 2017-05-29 Hiroki Sayama , Irene Pestov , Jeffrey Schmidt , Benjamin James Bush , Chun Wong , Junichi Yamanoi , Thilo Gross

In prokaryotic genomes the number of transcriptional regulators is known to quadratically scale with the total number of protein-coding genes. Toolbox model was recently proposed to explain this scaling for metabolic enzymes and their…

Molecular Networks · Quantitative Biology 2010-09-24 Tin Yau Pang , Sergei Maslov

Formal methods apply algorithms based on mathematical principles to enhance the reliability of systems. It would only be natural to try to progress from verification, model checking or testing a system against its formal specification into…

Software Engineering · Computer Science 2014-02-28 Gal Katz , Doron Peled

The interaction of distinct units in physical, social, biological and technological systems naturally gives rise to complex network structures. Networks have constantly been in the focus of research for the last decade, with considerable…

Physics and Society · Physics 2012-08-20 Tamás Nepusz , Tamás Vicsek

The vision of Organic Computing addresses challenges that arise in the design of future information systems that are comprised of numerous, heterogeneous, resource-constrained and error-prone components or devices. Here, the notion organic…

Networking and Internet Architecture · Computer Science 2012-04-26 Ingo Scholtes , Claudio Juan Tessone

Many complex systems in nature and society can be described in terms of networks capturing the intricate web of connections among the units they are made of. A key question is how to interpret the global organization of such networks as the…

Physics and Society · Physics 2007-05-23 Gergely Palla , Imre Derenyi , Illes Farkas , Tamas Vicsek

Complex networks are a powerful modeling tool, allowing the study of countless real-world systems. They have been used in very different domains such as computer science, biology, sociology, management, etc. Authors have been trying to…

Social and Information Networks · Computer Science 2014-02-04 Burcu Kantarcı , Vincent Labatut

We show that a common language can be used to unify the description of parametrically-coupled circuits--parametric amplifiers, frequency converters, and parametric nonreciprocal devices--with that of band-pass filter and impedance matching…

Applied Physics · Physics 2022-05-19 Ofer Naaman , Jose Aumentado

Assessing the synthesizability of inorganic materials is a grand challenge for accelerating their discovery using computations. Synthesis of a material is a complex process that depends not only on its thermodynamic stability with respect…

Complex systems are characterized by many interacting units that give rise to emergent behavior. A particularly advantageous way to study these systems is through the analysis of the networks that encode the interactions among the system's…

Physics and Society · Physics 2019-03-21 Alberto Aleta , Yamir Moreno

Many real life networks present an average path length logarithmic with the number of nodes and a degree distribution which follows a power law. Often these networks have also a modular and self-similar structure and, in some cases -…

Physics and Society · Physics 2010-02-17 Alicia Miralles , Francesc Comellas , Lichao Chen , Zhongzhi Zhang

We consider the basic features of complex dynamical and control systems. Special attention is paid to the problems of synthesis of dynamical models of complex systems, construction of efficient control models, and to the development of…

Computational Engineering, Finance, and Science · Computer Science 2009-07-03 Armen Bagdasaryan

The relations, rather than the elements, constitute the structure of networks. We therefore develop a systematic approach to the analysis of networks, modelled as graphs or hypergraphs, that is based on structural properties of…

Discrete Mathematics · Computer Science 2020-12-08 Marzieh Eidi , Amirhossein Farzam , Wilmer Leal , Areejit Samal , Jürgen Jost

Software systems emerge from mere keystrokes to form intricate functional networks connecting many collaborating modules, objects, classes, methods, and subroutines. Building on recent advances in the study of complex networks, I have…

Statistical Mechanics · Physics 2009-11-10 C. R. Myers
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