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Classical models for predicting current flow in excitable cells such as axons, originally proposed by Hodgkin and Huxley, rely on empirical voltage-gating parameters that quantify ion transport across sodium and potassium ion channels. We…

Biological Physics · Physics 2025-02-24 Vivaan Patel , Joshua D. Priosoetanto , Aashutosh Mistry , John Newman , Nitash P. Balsara

Salty water is the most abundant electrolyte aqueous mixture on Earth, however, very little is known about the NaCl-saturated solution interfacial free energy. Here, we provide the first direct estimation of this magnitude for several NaCl…

Soft Condensed Matter · Physics 2024-08-15 Ignacio Sanchez-Burgos , Jorge R. Espinosa

Ion transport in biological and synthetic nanochannels is characterized by phenomena such as ion current fluctuations and rectification. Recently, it has been demonstrated that nanofabricated synthetic pores can mimic transport properties…

Classical Physics · Physics 2009-11-13 I. D. Kosińska , I. Goychuk , M. Kostur , G. Schmid , P. Hänggi

The scattering effects are studied in nanometer-scaled double-gate MOSFET, using Monte Carlo simulation. The non-equilibrium transport in the channel is analyzed with the help of the spectroscopy of the number of scatterings experienced by…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 J. Saint Martin , A. Bournel , P. Dollfus

Possible mechanisms for over-limiting current (OLC) through aqueous ion-exchange membranes (exceeding diffusion limitation) have been debated for half a century. Flows consistent with electro-osmotic instability (EOI) have recently been…

Chemical Physics · Physics 2013-12-12 M. B. Andersen , M. van Soestbergen , A. Mani , H. Bruus , P. M. Biesheuvel , M. Z. Bazant

We study the effect of volumetric constraints on the structure and electronic transport properties of distilled water in a nanopore with embedded electrodes. Combining classical molecular dynamics simulations with quantum scattering theory,…

Soft Condensed Matter · Physics 2014-01-30 P. Boynton , M. Di Ventra

We investigate ionization at a solid-water interface in applied electric field. We attach an electrode to a dielectric film bearing silanol or carboxyl groups with an areal density $\Gamma_0$, where the degree of dissociation $\alpha$ is…

Soft Condensed Matter · Physics 2016-09-29 Ryuichi Okamoto , Akira Onuki

Cells and cellular organelles are encapsulated by nanometrically thin membranes whose main component is a lipid bilayer. In the presence of electric fields, the ion-impermeable lipid bilayer acts as a capacitor and supports a potential…

Soft Condensed Matter · Physics 2025-02-18 Shuozhen Zhao , Bhavya Balu , Zongxin Yu , Michael J. Miksis , Petia M. Vlahovska

It has been suggested that microtubules and other cytoskeletal filaments may act as electrical transmission lines. An electrical circuit model of the microtubule is constructed incorporating features of its cylindrical structure with…

Subcellular Processes · Quantitative Biology 2010-06-28 Holly Freedman , Vahid Rezania , Avner Priel , Eric Carpenter , Sergei Y. Noskovd , Jack A. Tuszynski

Fundamental understanding of ionic transport at the nanoscale is essential for developing biosensors based on nanopore technology and new generation high-performance nanofiltration membranes for separation and purification applications. We…

We introduce a theoretical and numerical method to investigate the flow of charged fluid mixtures under extreme confinement. We model the electrolyte solution as a ternary mixture, comprising two ionic species of opposite charge and a third…

Mesoscale and Nanoscale Physics · Physics 2012-09-13 Umberto Marini Bettolo Marconi , Simone Melchionna

The extent of ion pairing in solution is an important phenomenon to rationalise transport and thermodynamic properties of electrolytes. A fundamental measure of this pairing is the potential of mean force (PMF) between solvated ions. The…

Chemical Physics · Physics 2024-04-11 Niamh O'Neill , Benjamin X. Shi , Kara Fong , Angelos Michaelides , Christoph Schran

The properties of a partially ionized plasma in a long cylindrical tube subject to a uniform axial electric field are investigated. The plasma is maintained by an external ionizing source balanced by bulk and surface recombinations.…

Plasma Physics · Physics 2009-10-30 Joel L. Lebowitz , Alexander Rokhlenko

In this research, we explore how permanent charges affect the movement of ionic currents through ion channels. We use a quasi-one-dimensional classical Poisson-Nernst-Planck (PNP) model to study two types of ions, one positively charged and…

Dynamical Systems · Mathematics 2023-12-29 Hamid Mofidi

Aqueous solutions of LiCl are probably the most studied electrolyte solutions related to the complexity of liquid water at low temperatures. Despite the large amount of available experimental data hardly any computational studies were…

Soft Condensed Matter · Physics 2020-04-29 Philip H. Handle

The interface between a liquid and a solid is the location of plethora of intrincate mechanisms at the nanoscale, at the root of their specific emerging properties in natural processes or technological applications. However, while the…

Ion channels are specific proteins present in the membranes of living cells. They control the flow of specific ions through a cell, initiated by an ion channel's electrochemical gradient. In doing so, they control important physiological…

Subcellular Processes · Quantitative Biology 2012-09-14 Andrew Das Arulsamy

Fluid pumping and the generation of electric current by living tissues are required during morphogenetic processes and for maintainance of homeostasis. How these flows emerge from active and passive ion transport in cells has been well…

Biological Physics · Physics 2022-11-15 Marko Popović , Jacques Prost , Frank Jülicher

Transport of ions in molecular-scale confined spaces is central to all aspects of life and technology: into a crack, it may break steel within days; through a membrane separator, it determines the efficiency of electrochemical energy…

Soft Condensed Matter · Physics 2021-04-05 H. -W. Cheng , J. Dziadkowiec , V. Wieser , A. M. Imre , M. Valtiner

Molecular dynamics simulations have been performed on pure liquid water, aqueous solutions of sodium chloride, and polymer solutions exposed to a strong external electric field with the goal to gain molecular insight into the structural…

Soft Condensed Matter · Physics 2016-08-08 I. Nezbeda , J. Jirsák , F. Moučka , W. R. Smith
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