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We present a mathematical simplification for the evolutionary dynamics of a heritable trait within a two-sex population. This trait is assumed to control the timing of sex-specific life-history events, such as the age of sexual maturity and…

Populations and Evolution · Quantitative Biology 2019-07-04 M. H. Chan , K. Hawkes , P. S. Kim

Which factors govern the evolution of mutation rates and emergence of species? Here, we address this question using a first principles model of life where population dynamics of asexual organisms is coupled to molecular properties and…

Populations and Evolution · Quantitative Biology 2009-11-13 Muyoung Heo , Louis Kang , Eugene I. Shakhnovich

We model evolution of plants in a world, made up of different locations, with multiple environments (mutually exclusive and collectively exhaustive subsets of locations). Each environment (landmass) has temperature, rainfall, and other…

Populations and Evolution · Quantitative Biology 2019-05-27 Alexander , Khazatsky , Albert Yu , Zihao Zhao , Gabe Zuckerman

A population genetics formulation of Eigen's molecular quasispecies model is proposed and several simple replication landscapes are investigated analytically. Our results show a remarcable similarity to those obtained with the original…

Condensed Matter · Physics 2009-10-28 Domingos Alves , Jose Fernando Fontanari

The article describes the method of using computer-learning tools during the modeling of biological processes in the high school. The author developed web pages for online processing of the results of simulation of the genetic structure of…

Computers and Society · Computer Science 2018-12-04 Olena V. Komarova

The paper discusses a connection between asymmetric reproduction -- that is reproduction in a parent-child relationship where the parent does not mutate during reproduction --, the fact that all non-viral lifeforms bear genes of their…

Populations and Evolution · Quantitative Biology 2015-08-11 Norbert Michael Mayer

An integro-differential model for evolutionary dynamics with mutations is investigated by improving the understanding of its behavior using numerical simulations. The proposed numerical approach can handle also density dependent fitness,…

Populations and Evolution · Quantitative Biology 2020-01-27 A. L. Amadori , M. Briani , R. Natalini

All possible phenotypes are not equally accessible to evolving populations. In fact, only phenotypes of large size, i.e. those resulting from many different genotypes, are found in populations of sequences, presumably because they are…

Populations and Evolution · Quantitative Biology 2023-08-16 Pablo Catalán , Juan Antonio García-Martín , Jacobo Aguirre , José A. Cuesta , Susanna Manrubia

Social networks exhibit strikingly systematic patterns across a wide range of human contexts. While genetic variation accounts for a significant portion of the variation in many complex social behaviors, the heritability of egocentric…

Genomics · Quantitative Biology 2009-02-11 James H. Fowler , Christopher T. Dawes , Nicholas A. Christakis

In this research, we present a generalized quasispecies model in which population growth is governed by an arbitrary nonlinear function incorporating time delays. We begin by demonstrating that, under the constant population constraint, the…

Dynamical Systems · Mathematics 2025-08-19 Nolbert Morales , Edward A. Turner

The modelling of evolutionary game dynamics in finite populations requires microscopic processes that determine how strategies spread. The exact details of these processes are often chosen without much further consideration. Different types…

Populations and Evolution · Quantitative Biology 2014-06-17 Bin Wu , Benedikt Bauer , Tobias Galla , Arne Traulsen

In this paper we consider a microscopic model of a simple ecosystem. The basic ingredients of this model are individuals, and both the phenotypic and genotypic levels are taken in account. The model is based on a long range cellular…

Statistical Mechanics · Physics 2007-05-23 Franco Bagnoli , Michele Bezzi

Most conspicuous organisms are multicellular and most multicellular organisms develop somatic cells to perform specific, non-reproductive tasks. The ubiquity of this division of labor suggests that it is highly advantageous. In this paper,…

Populations and Evolution · Quantitative Biology 2008-01-18 Martin Willensdorfer

Collective cell migration plays a crucial role in numerous biological processes, including tumour growth, wound healing, and the immune response. Often, the migrating population consists of cells with various different phenotypes. This…

Populations and Evolution · Quantitative Biology 2025-04-01 Rebecca M. Crossley , Philip K. Maini , Ruth E. Baker

A simplified form of the time dependent evolutionary dynamics of a quasispecies model with a rugged fitness landscape is solved via a mapping onto a random flux model whose asymptotic behavior can be described in terms of a random walk. The…

Statistical Mechanics · Physics 2009-11-11 Clement Sire , Satya N. Majumdar , David S. Dean

Mathematical models play an increasingly important role in the interpretation of biological experiments. Studies often present a model that generates the observations, connecting hypothesized process to an observed pattern. Such generative…

Populations and Evolution · Quantitative Biology 2014-06-18 Steven A. Frank

In this review some simple models of asexual populations evolving on smooth landscapes are studied. The basic model is based on a cellular automaton, which is analyzed here in the spatial mean-field limit. Firstly, the evolution on a fixed…

Statistical Mechanics · Physics 2016-11-23 Franco Bagnoli , Michele Bezzi

In many models of genotypic evolution, the vector of genotype populations satisfies a system of linear ordinary differential equations. This system of equations models a competition between differential replication rates (fitness) and…

Populations and Evolution · Quantitative Biology 2009-11-13 Charles L. Epstein

How to define and use the concept of inclusive fitness is a contentious topic in evolutionary theory. Inclusive fitness can be used to calculate selection on a focal gene, but it is also applied to whole organisms. Individuals are then…

Populations and Evolution · Quantitative Biology 2019-06-11 Lutz Fromhage , Michael D Jennions

Here we study how mutations which change physical properties of cell proteins (stability) impact population survival and growth. In our model the genotype is presented as a set of N numbers, folding free energies of cells N proteins.…

Biomolecules · Quantitative Biology 2009-03-10 Peiqiu Chen , Eugene I. Shakhnovich
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