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Integral membrane proteins deform the surrounding bilayer creating long-ranged forces that influence distant proteins. These forces can be attractive or repulsive, depending on the proteins' shape, height, contact angle with the bilayer, as…

Statistical Mechanics · Physics 2007-05-23 Tom Chou , Ken S. Kim , George Oster

We analyze the Thermodynamic Bethe Ansatz equations of the one-dimensional half-filled Hubbard model in the "spin-disordered regime", which is characterized by the temperature being much larger than the magnetic energy scale but small…

Strongly Correlated Electrons · Physics 2009-11-11 S. Ejima , F. H. L. Essler , F. Gebhard

The dynamics of folding of proteins is studied by means of a phenomenological master equation. The energy distribution is taken as a truncated exponential for the misfolded states plus a native state sitting below the continuum. The…

Soft Condensed Matter · Physics 2007-05-23 Estelle Pitard , Henri Orland

Measurements of temperature-dependent resistance and magnetization under hydrostatic pressures up to 2.13 GPa are reported for single-crystalline, superconducting BaBi$_3$. A temperature - pressure phase diagram is determined and the…

In the framework of a lattice-model study of protein folding, we investigate the interplay between designability, thermodynamic stability, and kinetics. To be ``protein-like'', heteropolymers must be thermodynamically stable, stable against…

Statistical Mechanics · Physics 2009-10-31 Régis Mélin , Hao Li , Ned S. Wingreen , Chao Tang

A microscopic model of the lipid membrane is constructed that provides analytically tractable description of the physical mechanism of the first order liquid-gel phase transition. We demonstrate that liquid-gel phase transition is…

Soft Condensed Matter · Physics 2018-07-04 Boris Kheyfets , Timur Galimzyanov , Sergei Mukhin

Scaling of folding properties of proteins is studied in a toy system -- the lattice Go model with various two- and three- dimensional geometries of the maximally compact native states. Characteristic folding times grow as power laws with…

Statistical Mechanics · Physics 2009-10-31 Marek Cieplak , Trinh Xuan Hoang , Mai Suan Li

We present, theoretical predictions and Monte Carlo simulations, for a simple three matrix model that exhibits an exotic phase transition. The nature of the transition is very different if approached from the high or low temperature side.…

High Energy Physics - Theory · Physics 2010-01-15 Rodrigo Delgadillo-Blando , Denjoe O'Connor , Badis Ydri

The imaginary time path integral formalism is applied to a nonlinear Hamiltonian for a short fragment of heterogeneous DNA with a stabilizing solvent interaction term. Torsional effects are modeled by a twist angle between neighboring base…

Biomolecules · Quantitative Biology 2011-09-19 Marco Zoli

Using a structure-based coarse-grained model of proteins, we study the mechanism of unfolding of knotted proteins through heating. We find that the dominant mechanisms of unfolding depend on the temperature applied and are generally…

Biomolecules · Quantitative Biology 2017-01-23 Yani Zhao , Mateusz Chwastyk , Marek Cieplak

We study the geometric properties of the energy landscape of coarse-grained, off-lattice models of polymers by endowing the configuration space with a suitable metric, depending on the potential energy function, such that the dynamical…

Statistical Mechanics · Physics 2007-05-23 Lorenzo N. Mazzoni , Lapo Casetti

In the cell, proteins fold and perform complex functions through global structural rearrangements. Function requires a protein to be at the brink of stability to be susceptible to small environmental fluctuations, yet stable enough to…

The thermodynamical properties of heterogeneous DNA sequences are computed by path integral techniques applied to a nonlinear model Hamiltonian. The base pairs relative displacements are interpreted as time dependent paths whose amplitudes…

Statistical Mechanics · Physics 2010-05-12 Marco Zoli

The thermal and mechanical behaviors of powders are important for various additive manufacturing technologies. For powder bed fusion, capturing the temperature profile and the packing structure of the powders prior to melting is challenging…

Soft Condensed Matter · Physics 2024-02-26 Sudeshna Roy , Hongyi Xiao , Vasileios Angelidakis , Thorsten Pöschel

A master equation describing the evolution of averaged molecular state occupancies in molecular systems where alternation of molecular energy levels is caused by discrete dichotomous and trichotomous stochastic fields, is derived. This…

Chemical Physics · Physics 2012-12-06 E. G. Petrov , V. I. Teslenko

Models of protein energetics which neglect interactions between amino acids that are not adjacent in the native state, such as the Go model, encode or underlie many influential ideas on protein folding. Implicit in this simplification is a…

Biomolecules · Quantitative Biology 2009-10-08 Brian C. Gin , Juan P. Garrahan , Phillip L. Geissler

We study a homopolymer model of a protein chain, where each monomer carries a dipole moment. To mimic the geometry of the peptidic bond, these dipoles are constrained to be locally perpendicular to the chain. The tensorial character of the…

Soft Condensed Matter · Physics 2009-10-30 E. Pitard , T. Garel , H. Orland

We present a numerical Monte Carlo analysis of a continuos spin Ising chain that can describe the statistical proterties of folded proteins. We find that depending on the value of the Metropolis temperature, the model displays the three…

Statistical Mechanics · Physics 2011-02-01 M. N. Chernodub , Martin Lundgren , Antti J. Niemi

Nonnative residual interactions have attracted increasing attention in recent protein folding researches. Experimental and theoretical investigations had been set out to catch nonnative contacts that might dominate key events in protein…

Biological Physics · Physics 2017-01-30 Yunxiang Sun , Dengming Ming

By combining different ideas, a general and efficient protocol to deal with discontinuous phase transitions at low temperatures is proposed. For small $T$'s, it is possible to derive a generic analytic expression for appropriate order…

Statistical Mechanics · Physics 2015-06-03 C. E. Fiore , M. G. E. da Luz