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Microfluidics, the study of fluids in microscopic channels, has led to important advances in fields as diverse as microelectronics, biotechnology and chemistry. Microfluidic research is primarily based on the use of microfluidic chips,…

Systems and Control · Electrical Eng. & Systems 2024-07-15 Jorge Vicente Martinez , Edgar Ramirez-Laboreo , Pablo Calderon Gil

Advances in molecular biology are enabling rapid and efficient analyses for effective intervention in domains such as biology research, infectious disease management, food safety, and biodefense. The emergence of microfluidics and…

Quantitative Methods · Quantitative Biology 2017-03-28 Harikrishnan Jayamohan , Valentin Romanov , Huizhong Li , Jiyoung Son , Raheel Samuel , John Nelson , Bruce Gale

Microfluidic chips provide unparalleled control over droplets and jets, which have advanced all natural sciences. However, microfluidic applications could be vastly expanded by increasing the per-channel throughput and directly exploiting…

Microfluidics and lab-on-a-chip technologies have made it possible to manipulate small volume liquids with unprecedented resolution, automation and integration. However, most current microfluidic systems still rely on bulky off-chip…

Instrumentation and Detectors · Physics 2014-05-22 Baichen Li , Lin Li , Allan Guan , Quan Dong , Kangcheng Ruan , Ronggui Hu , Zhenyu Li

A new type of microfluidic system for biological cell manipulation, a CMOS/microfluidic hybrid, is demonstrated. The hybrid system starts with a custom-designed CMOS (complementary metal-oxide semiconductor) chip fabricated in a…

Quantitative Methods · Quantitative Biology 2007-05-23 Hakho Lee , Yong Liu , Donhee Ham , Robert M. Westervelt

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

Soft Condensed Matter · Physics 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture

Microfluidic devices have been the subject of considerable attention in recent years. The development of novel microfluidic devices, their evaluation, and their validation requires simulations. While common methods based on Computational…

Fluid Dynamics · Physics 2024-11-05 Maria Emmerich , Florina Costamoling , Robert Wille

Hyperpolarized nuclear magnetic resonance and lab-on-a-chip microfluidics are two dynamic, but until recently quite distinct, fields of research. Recent developments in both areas increased their synergistic overlap. By microfluidic…

Chemical Physics · Physics 2021-09-29 James Eills , William Hale , Marcel Utz

Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers…

Instrumentation and Detectors · Physics 2015-06-22 George Korir , Manu Prakash

High-density microfluidics is becoming an important experimental platform for studying complex biological systems such as synthetic gene regulatory networks, molecular biocomputating of engineered cells, distributing rapid point-of-care…

Biological Physics · Physics 2021-07-21 Sankar Raju Narayanasamy , Ramakrishna Vasireddi , Hoi-Ying Holman

Microfluidics-based biochips are soon expected to revolutionize clinical diagnosis, DNA sequencing, and other laboratory procedures involving molecular biology. Most microfluidic biochips are based on the principle of continuous fluid flow…

Hardware Architecture · Computer Science 2011-11-09 Fei Su , Krishnendu Chakrabarty

Pumping fluids without an aid of an external power source are desirable in a number of applications ranging from a cooling of microelectronic circuits to Micro Total Analysis Systems (micro-TAS). Although, several microfluidic pumps exist,…

Applied Physics · Physics 2019-09-25 Prasoon Kumar , Prasanna S Gandhi , Mainak Majumder

An increasing number of applications in biology, chemistry, and material sciences require fluid manipulation beyond what is possible with current automated pipette handlers, such as gradient generation, interface reactions, reagent…

Applied Physics · Physics 2020-08-25 Pierre-Alexandre Goyette , Étienne Boulais , Maude Tremblay , Thomas Gervais

Microfluidics involves the manipulation of flows at the microscale, typically requiring external power sources to generate pressure gradients. Alternatively, harnessing flows from active fluids, which are usually chaotic, has been proposed…

It may be possible to reinvent how microelectronics are made using a two step process: (1) Synthesizing modular, nanometer-scale components -- transistors, sensors, and other devices -- and suspending them in a liquid "ink" for storage or…

Computers and Society · Computer Science 2023-03-21 Michael Filler , Benjamin Reinhardt

Microfluidic valves play a key role within microfluidic systems by regulating fluid flow through distinct microchannels, enabling many advanced applications in medical diagnostics, lab-on-chips, and laboratory automation. While microfluidic…

Materials Science · Physics 2023-12-19 Tinku Supakar , David Space , Sophy Meija , Rou Yu Tan , Jeffrey R. Alston , Eric A. Josephs

Recent progress in colloidal science has led to elaborate self-assembled structures whose complexity raises hopes for elaborating new materials. However, the throughputs are extremely low and consequently, the chance to produce materials of…

Soft Condensed Matter · Physics 2014-09-16 Bingqing Shen , Joshua Ricouvier , Mathilde Reyssat , Florent Malloggi , Patrick Tabeling

Microfluidics has revolutionized control over small volumes through the use of physical barriers. However, the rigidity of these barriers limits flexibility in applications. We present an optofluidic toolbox that leverages structured light…

Microfluidic droplet screens serve as an innovative platform for high-throughput biotechnology, enabling significant advancements in discovery, product optimization, and analysis. This review sheds light on the emerging trend of interaction…

Quantitative Methods · Quantitative Biology 2023-09-11 Carolus Vitalis , Tobias Wenzel

The complexity of droplet microfluidics grows by implementing parallel processes and multiple functionalities on a single device. This poses a challenge to the engineer designing the microfluidic networks. In today's design processes, the…

Fluid Dynamics · Physics 2018-10-03 Andreas Grimmer , Medina Hamidović , Werner Haselmayr , Robert Wille
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