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Information is increasingly being viewed as a resource used by organisms to increase their fitness. Indeed, it has been formally shown that there is a sensible way to assign a reproductive value to information and it is non-negative.…

Populations and Evolution · Quantitative Biology 2017-05-03 Jared M. Field , Michael B. Bonsall

A variety of biomolecular systems rely on exploratory dynamics to reach target locations or states within a cell. Without a mechanism to remotely sense and move directly towards a target, the system must sample over many paths, often…

Biological Physics · Physics 2025-09-01 Elena F Koslover , Milo M Lin , Rob Phillips

Adaptive sampling theory has shown that, with proper assumptions on the signal class, algorithms exist to reconstruct a signal in $\mathbb{R}^{d}$ with an optimal number of samples. We generalize this problem to the case of spatial signals,…

Machine Learning · Statistics 2017-02-20 John Lipor , Brandon Wong , Donald Scavia , Branko Kerkez , Laura Balzano

Bayesian optimization (BO) is increasingly employed in critical applications such as materials design and drug discovery. An increasingly popular strategy in BO is to forgo the sole reliance on high-fidelity data and instead use an ensemble…

Machine Learning · Statistics 2023-03-22 Zahra Zanjani Foumani , Mehdi Shishehbor , Amin Yousefpour , Ramin Bostanabad

In contrast with animal communication systems, diversity is characteristic of almost every aspect of human language. Languages variously employ tones, clicks, or manual signs to signal differences in meaning; some languages lack the…

Physics and Society · Physics 2013-02-14 Andrea Baronchelli , Nick Chater , Romualdo Pastor-Satorras , Morten H. Christiansen

This position paper argues that the Baldwin effect is widely misunderstood by the evolutionary computation community. The misunderstandings appear to fall into two general categories. Firstly, it is commonly believed that the Baldwin effect…

Machine Learning · Computer Science 2007-05-23 Peter D. Turney

In multiple testing scenarios, typically the sign of a parameter is inferred when its estimate exceeds some significance threshold in absolute value. Typically, the significance threshold is chosen to control the experimentwise type I error…

Methodology · Statistics 2018-01-03 Chaoyu Yu , Peter D. Hoff

A principal decides whether to approve an agent based on a noisy signal (e.g., test scores) generated by the agent. High-quality agents can produce high signals on average at lower cost, but the realizations are subject to noise that…

Theoretical Economics · Economics 2026-05-14 Shuhua Si , Yangfan Zhou

Considerable evidence suggests that anticipating sudden shifts from one state to another in bistable dynamical systems is a challenging task, examples include ecosystems, financial markets, complex diseases, etc. In this paper, we…

Adaptation and Self-Organizing Systems · Physics 2016-03-23 Yogita Sharma , Partha Sharathi Dutta , A. K. Gupta

Any organism is embedded in an environment that changes over time. The timescale for and statistics of environmental change, the precision with which the organism can detect its environment, and the costs and benefits of particular protein…

Quantitative Methods · Quantitative Biology 2023-07-19 David A. Sivak , Matt Thomson

An inductive learning algorithm takes a set of data as input and generates a hypothesis as output. A set of data is typically consistent with an infinite number of hypotheses; therefore, there must be factors other than the data that…

Machine Learning · Computer Science 2007-05-23 Peter D. Turney

Artificial intelligence (AI) is playing an increasingly significant role in our everyday lives. This trend is expected to continue, especially with recent pushes to move more AI to the edge. However, one of the biggest challenges associated…

Machine Learning · Computer Science 2020-11-18 Cory Merkel

Cooperative interactions among the binding of multiple signaling molecules is a common mechanism for enhancing the sensitivity of biological signaling systems. It is widely assumed that this increase in sensitivity of the mean response…

Molecular Networks · Quantitative Biology 2007-05-23 William Bialek , Sima Setayeshgar

This paper explores the design of convolutional codes for varying constraint lengths, focusing on their role in error correction in digital communication systems. Convolutional codes are essential in achieving reliable data transmission…

Information Theory · Computer Science 2024-10-03 Parag Dhounde , Avinash Bhute

Standard models of biologically realistic or biologically inspired reinforcement learning employ a global error signal, which implies the use of shallow networks. On the other hand, error backpropagation allows the use of networks with…

Machine Learning · Computer Science 2023-09-14 Sama Daryanavard , Bernd Porr

Early warning signals have been proposed to forecast the possibility of a critical transition, such as the eutrophication of a lake, the collapse of a coral reef, or the end of a glacial period. Because such transitions often unfold on…

Populations and Evolution · Quantitative Biology 2012-10-04 Carl Boettiger , Alan Hastings

Information extracted from electrohysterography recordings could potentially prove to be an interesting additional source of information to estimate the risk on preterm birth. Recently, a large number of studies have reported near-perfect…

Understanding a neural code requires knowledge both of the elementary symbols that transmit information and of the algorithm for translating these symbols into sensory signals or motor actions. We show that these questions can be separated:…

Biological Physics · Physics 2007-05-23 N. Brenner , S. P. Strong , R. Koberle , W. Bialek , R. de Ruyter van Steveninck

Species evolution is essentially a random process of interaction between biological populations and their environments. As a result, some physical parameters in evolution models are subject to statistical fluctuations. In this paper, two…

Populations and Evolution · Quantitative Biology 2015-06-02 Duo-Fang Li , Tian-Guang Cao , Jin-Peng Geng , Li-Hua Qiao , Jian-Zhong Gu , Yong Zhan

We show how sign problems in simulations of many-body systems can manifest themselves in the form of heavy-tailed correlator distributions, similar to what is seen in electron propagation through disordered media. We propose an alternative…

High Energy Physics - Lattice · Physics 2013-03-01 Michael G. Endres , David B. Kaplan , Jong-Wan Lee , Amy N. Nicholson