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The need for high-throughput, precise, and meaningful methods for measuring behavior has been amplified by our recent successes in measuring and manipulating neural circuitry. The largest challenges associated with moving in this direction,…

Biological Physics · Physics 2017-12-18 Gordon J. Berman

Signal processing in biological systems is delicately executed by specialised networks, which are modular assemblies of network motifs. The motifs are independently functional circuits found in enormous numbers in any living cell. A very…

Molecular Networks · Quantitative Biology 2016-12-08 Tarunendu Mapder

The paper addresses the exact linearization of flat nonlinear discrete-time systems by generalized static or dynamic feedbacks which may also depend on forward-shifts of the new input. We first investigate the question which forward-shifts…

Optimization and Control · Mathematics 2022-12-29 Bernd Kolar , Johannes Diwold , Conrad Gstöttner , Markus Schöberl

Predictive coding offers a potentially unifying account of cortical function -- postulating that the core function of the brain is to minimize prediction errors with respect to a generative model of the world. The theory is closely related…

Artificial Intelligence · Computer Science 2022-07-14 Beren Millidge , Anil Seth , Christopher L Buckley

The activity of neurons within brain circuits has been ubiquitously reported to be correlated. The impact of these correlations on brain function has been extensively investigated. Correlations can in principle increase or decrease the…

Neurons and Cognition · Quantitative Biology 2025-07-24 Miguel Ibáñez-Berganza , Giulio Bondanelli , Stefano Panzeri

A fundamental problem in neuroscience is to understand how sequences of action potentials ("spikes") encode information about sensory signals and motor outputs. Although traditional theories of neural coding assume that information is…

Neurons and Cognition · Quantitative Biology 2022-10-12 Kyle H. Srivastava , Caroline M. Holmes , Michiel Vellema , Andrea Pack , Coen P. H. Elemans , Ilya Nemenman , Samuel J. Sober

Brain-controlled robots are a promising new type of assistive device for severely impaired persons. Little is however known about how to optimize the interaction of humans and brain-controlled robots. Information about the human's perceived…

Inverse problems exist in a wide variety of physical domains from aerospace engineering to medical imaging. The goal is to infer the underlying state from a set of observations. When the forward model that produced the observations is…

Machine Learning · Computer Science 2023-01-06 Chelsea Sidrane , Sydney Katz , Anthony Corso , Mykel J. Kochenderfer

We introduce and study methods for inferring and learning from correspondences among neurons. The approach enables alignment of data from distinct multiunit studies of nervous systems. We show that the methods for inferring correspondences…

Neurons and Cognition · Quantitative Biology 2015-01-28 Ashish Kapoor , E. Paxon Frady , Stefanie Jegelka , William B. Kristan , Eric Horvitz

Vision-Language Models (VLMs) have recently gained attention due to their competitive performance on multiple downstream tasks, achieved by following user-input instructions. However, VLMs still exhibit several limitations in visual…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Simone Alghisi , Gabriel Roccabruna , Massimo Rizzoli , Seyed Mahed Mousavi , Giuseppe Riccardi

The study of the brain's representations of uncertainty is a central topic in neuroscience. Unlike most quantities of which the neural representation is studied, uncertainty is a property of an observer's beliefs about the world, which…

Neurons and Cognition · Quantitative Biology 2023-10-12 Edgar Y Walker , Stephan Pohl , Rachel N Denison , David L Barack , Jennifer Lee , Ned Block , Wei Ji Ma , Florent Meyniel

Representations learned by convolutional neural networks (CNNs) exhibit a remarkable resemblance to information processing patterns observed in the primate visual system on large neuroimaging datasets collected under diverse, naturalistic…

Neurons and Cognition · Quantitative Biology 2026-03-16 Dora Gozukara , Nasir Ahmad , Katja Seeliger , Djamari Oetringer , Linda Geerligs

Understanding human motion processing is essential for building reliable, human-centered computer vision systems. Although deep neural networks (DNNs) achieve strong performance in optical flow estimation, they remain less robust than…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Isabella Elaine Rosario , Fan L. Cheng , Zitang Sun , Nikolaus Kriegeskorte

An heuristic signal processing scheme recently introduced shows how brain signals can be efficiently represented by a sparse spatiotemporal point process. The approach has been validated already for different relevant conditions…

Neurons and Cognition · Quantitative Biology 2017-07-05 Ignacio Cifre , Mahdi Zarepour , Silvina G Horovitz , Sergio Cannas , Dante R Chialvo

Rule-based models are attractive for various tasks because they inherently lead to interpretable and explainable decisions and can easily incorporate prior knowledge. However, such systems are difficult to apply to problems involving…

Computation and Language · Computer Science 2019-06-17 Leon Weber , Pasquale Minervini , Jannes Münchmeyer , Ulf Leser , Tim Rocktäschel

Despite recent advances in the field of explainable artificial intelligence systems, a concrete quantitative measure for evaluating the usability of such systems is nonexistent. Ensuring the success of an explanatory interface in…

Human-Computer Interaction · Computer Science 2020-10-26 Byung Hyung Kim , Seunghun Koh , Sejoon Huh , Sungho Jo , Sunghee Choi

Precise control of neural activity -- modulating target neurons deep in the brain while leaving nearby neurons unaffected -- is an outstanding challenge in neuroscience, generally approached using invasive techniques. This study…

Neurons and Cognition · Quantitative Biology 2025-06-17 Guy Gaziv , Sarah Goulding , Ani Ayvazian-Hancock , Yoon Bai , James J. DiCarlo

Humans race drones faster than algorithms, despite being limited to a fixed camera angle, body rate control, and response latencies in the order of hundreds of milliseconds. A better understanding of the ability of human pilots of selecting…

Robotics · Computer Science 2021-03-09 Christian Pfeiffer , Davide Scaramuzza

We present a randomized controlled trial for a model-in-the-loop regression task, with the goal of measuring the extent to which (1) good explanations of model predictions increase human accuracy, and (2) faulty explanations decrease human…

Machine Learning · Computer Science 2020-07-27 Eric Chu , Deb Roy , Jacob Andreas

This book chapter describes how spectral correlations in scattered light fields can be utilized for high-precision time-of-flight sensing. The chapter should serve as a gentle introduction and is intended for computational imaging…

Optics · Physics 2022-09-13 Florian Willomitzer