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High resolution low angle x-ray data are reported for the gel phase of DPPC lipid bilayers, extending the previous q range of 1.0 {\AA}-1 to 1.3 {\AA}-1, and employing a new technique to obtain more accurate intensities and form factors…

Biological Physics · Physics 2019-03-27 John F Nagle , Pierre Cognet , Fernando G. Dupuy , Stephanie Tristram-Nagle

A new method is proposed for the analysis of specular and off-specular reflectivity from supported lipid bilayers. Both thermal fluctuations and the "static" roughness induced by the substrate are carefully taken into account. Examples from…

Soft Condensed Matter · Physics 2009-10-08 Linda Malaquin , Thierry Charitat , Jean Daillant

We have developed a global analysis model for randomly oriented, fully hydrated inverted hexagonal (H$_\text{II}$) phases formed by many amphiphiles in aqueous solution, including membrane lipids. The model is based on a structure factor…

Biomolecules · Quantitative Biology 2019-04-08 Moritz P. K. Frewein , Michael Rumetshofer , Georg Pabst

In this paper, we extend a recently developed machine-learning (ML) based CREASE-2D method to analyze the entire two-dimensional (2D) scattering pattern obtained from small angle X-ray scattering measurements of supramolecular dipeptide…

Soft Condensed Matter · Physics 2025-04-08 Nitant Gupta , Sri V. V. R. Akepati , Simona Bianco , Jay Shah , Dave J. Adams , Arthi Jayaraman

On the basis of the separated form-factor model, a code for fitting the small-angle neutron scattering spectra of the polydispersed vesicle population has been developed. Vesicle and membrane bilayer parameters are analyzed for various…

Chemical Physics · Physics 2007-05-23 E. V. Zemlyanaya , M. A. Kiselev , V. K. Aswal

Scattering structure factors provide essential insight into material properties and are routinely obtained in experiments, computer simulations, and theoretical analyses. Different approaches favor different geometries of the material. In…

Soft Condensed Matter · Physics 2018-05-15 Yongtian Luo , Lutz Maibaum

Highly oriented solid-supported lipid membranes in stacks of controlled number $N \simeq 16$ (oligo-membranes) have been prepared by spin-coating using the uncharged lipid model system 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). The…

Soft Condensed Matter · Physics 2015-04-10 Ulrike Mennicke , Doru Constantin , Tim Salditt

We present a theoretical justification for a method of extracting of supplementary information for the phase retrieval procedure taken from diffraction of fs-pulses from X-ray Free Electron Laser facilities. The approach is based on…

Materials Science · Physics 2015-02-18 A. Leonov , D. Ksenzov , A. Benediktovitch , I. Feranchuk , U. Pietsch

To explore dense packings of soft colloids, scattering experiments are ideal to access the structure factor. However, for soft microgels determination of the structure factor is difficult because of the low contrast of the polymer network…

We present a measurement protocol and a data reduction workflow for obtaining single-crystal X-ray total-scattering datasets that capture both Bragg-peak and diffuse scattering intensities on an absolute (electrons2/atom) scale. We further…

Materials Science · Physics 2025-09-23 S. Gorfman , M. Eremenko , V. Krayzman , A. Bosak , P. Y. Zavalij , I. Levin

Molecular and polymeric crystals show a wide range of functional properties that arise from the interplay between the atomic-scale structure of their constituent molecules and the organization of these molecules within the crystal lattice…

We use a coarse-grained molecular model to study the self-assembly process of complexes of cationic and neutral lipids with DNA molecules ("lipoplexes") - a promising nonviral carrier of DNA for gene therapy. We identify the resulting…

Soft Condensed Matter · Physics 2011-05-31 Oded Farago , Niels Grønbech-Jensen

The response kinetics of liquid crystalline phosphatidylcholine bilayer stacks to rapid, IR-laser induced temperature jumps has been studied by millisecond time-resolved x-ray diffraction. The system reacts on the fast temperature change by…

Biological Physics · Physics 2007-05-23 Georg Pabst , Michael Rappolt , Heinz Amenitsch , Sigrid Bernstorff , Peter Laggner

Nanobeam electron diffraction can probe local structural properties of complex crystalline materials including phase, orientation, tilt, strain, and polarization. Ideally, each diffraction pattern from a projected area of a few unit cells…

The adsorption of polymer and surfactant molecules onto colloidal particles or droplets in solution can be characterized non-destructively by scattering techniques. In a first part, the general framework of Dynamic Light Scattering, Small…

Soft Condensed Matter · Physics 2007-05-24 Julian Oberdisse

The structure of membrane-active peptides and their interaction with lipid bilayers can be studied in oriented lipid membranes deposited on solid substrates. Such systems are desirable for a number of surface-sensitive techniques. Here we…

Soft Condensed Matter · Physics 2015-04-10 Chenghao Li , Doru Constantin , Tim Salditt

We outline a strategy for quantitatively evaluating the conformational characteristics of self-assembled structures using the techniques of contrast variation small angle neutron scattering. By means of basis function expansion, a case…

Soft Condensed Matter · Physics 2021-10-27 Albert Y. Ho , Guan-Rong Huang , Wei-Ren Chen

Lipid nanoparticles own a remarkable potential in nanomedicine, only partially disclosed. While the clinical use of liposomes and cationic lipid-nucleic acid complexes is well-established, liquid lipid nanoparticles (nanoemulsions), solid…

Near total reflection regime has been widely used in X-ray science, specifically in grazing incidence small angle X-ray scattering and in hard X-ray photoelectron spectroscopy. In this work, we introduce some practical aspects of using near…

We study a continuum model of the lipid bilayer based on minimizing the free energy of a mixture of water and lipid molecules. This paper extends previous work by Blom & Peletier (2004) in the following ways. (a) It formulates a more…

Soft Condensed Matter · Physics 2020-06-05 Phillip L. Wilson , Huaxiong Huang , Shu Takagi
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