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With the help of a mathematical model, the metabolic process of the Krebs cycle is studied. The autocatalytic processes resulting in both the formation of the self-organization in the Krebs cycle and the appearance of a cyclicity of its…

Molecular Networks · Quantitative Biology 2017-10-26 V. I. Grytsay , I. V. Musatenko

The experiments conducted by various scientific groups indicate that, in dense two-dimensional systems of elongated particles subjected to vibration, the pattern formation is possible. Computer simulations have evidenced that the random…

Inert particles suspended in active fluids of self-propelled particles are known to often exhibit enhanced diffusion and novel coherent structures. Here we numerically investigate the dynamical behavior and self-organization in a system…

Soft Condensed Matter · Physics 2016-07-04 Kyongmin Yeo , Enkeleida Lushi , Petia M. Vlahovska

Epithelial cell clusters often move collectively on a substrate. Mechanical signals play a major role in organizing this behavior. There are a number of experimental observations in these systems which await a comprehensive explanation.…

Biological Physics · Physics 2021-01-22 Youyuan Deng , Herbert Levine , Xiaoming Mao , Leonard M. Sander

The evolution of multicellular organisms from monocellular ancestors represents one of the greatest advances of the history of life. The assembly of such multicellular organisms requires signalling and response between cells: over millions…

Cell Behavior · Quantitative Biology 2007-05-23 Graeme J. Ackland , Richard D. L. Hanes , Morrel H. Cohen

We study the threshold conditions of spatial self organization combined with collective coherent optical backscattering of a thermal gaseous beam moving in a high Q ring cavity with counter propagating pump. We restrict ourselves to the…

Quantum Physics · Physics 2009-11-13 C. Maes , J. Asboth , H. Ritsch

We present a simple model that describes the motion of a single chemotactic cell exposed to a traveling wave of the chemoattractant. The model incorporates two types of responses to stimulation by the chemoattractant, i.e., change in…

Biological Physics · Physics 2011-10-26 Masatomo Iwasa , Ryosuke Ishiwata

In recent years the functionality of synthetic active microparticles has edged even closer to that of their biological counterparts. However, we still lack the understanding needed to recreate at the microscale key features of autonomous…

Soft Condensed Matter · Physics 2024-10-28 Philipp W. A. Schönhöfer , Sharon C. Glotzer

We propose and study a hydrodynamic model for pattern formation in mixtures of molecular motors and microtubules. The steady state patterns we obtain in different regimes of parameter space include arrangements of vortices and asters…

Statistical Mechanics · Physics 2009-11-10 Sumithra Sankararaman , Gautam I. Menon , P. B. Sunil Kumar

Active fluids, such as cytoskeletal filaments, bacterial colonies and epithelial cell layers, exhibit distinctive orientational coherence, often characterized by nematic order and topological defects. By contrast, little is known about…

Soft Condensed Matter · Physics 2021-04-07 Mattia Serra , Linnea Lemma , Luca Giomi , Zvonimir Dogic , L. Mahadevan

The actin cytoskeleton is remarkably adaptable and multifunctional. It often organizes into nematic bundles such as contractile rings or stress fibers. However, how a uniform and isotropic actin gel self-organizes into dense nematic bundles…

We investigate the final stage of cytokinesis in two types of amoeba, pointing out the existence of biphasic furrow contraction. The first phase is characterized by a constant contraction rate, is better studied, and seems universal to a…

Cell Behavior · Quantitative Biology 2007-05-23 D. Biron , P. Libros , D. Sagi , D. Mirelman , E. Moses

We study numerically the phases and dynamics of a dense collection of self-propelled particles with soft repulsive interactions in two dimensions. The model is motivated by recent in vitro experiments on confluent monolayers of migratory…

Soft Condensed Matter · Physics 2015-05-28 Silke Henkes , Yaouen Fily , M. Cristina Marchetti

Cell crawling requires the generation of intracellular forces by the cytoskeleton and their transmission to an extracellular substrate through specific adhesion molecules. Crawling cells show many features of excitable systems, such as…

Biological Physics · Physics 2020-06-02 Pierre Sens

In this research, formation of finite two-dimensional (2D) plasma crystals was numerically simulated. The structure was investigated for systems with various Debye length and it was found there is a transition from a complete hexagonal…

Plasma Physics · Physics 2007-07-27 K. Qiao , T. W. Hyde

Self-organization of hydrogen bubbles generated by laser-treated areas of an aluminum plate etched in a basic aqueous solution of ammonia is studied experimentally and theoretically. A dynamics of establishment of stationary pattern of gas…

Fluid Dynamics · Physics 2012-09-28 N. A. Kirichenko , E. V. Barmina , P. G. Kuzmin , G. A. Shafeev

We theoretically show that the topology of a non-simply-connected annular atomic Bose-Einstein condensate enforces the inner surface waves to be always excited with outer surface excitations and that the inner surface modes are associated…

Quantum Gases · Physics 2012-07-26 S. J. Woo , Young-Woo Son

Living cells exhibit a complex organization comprising numerous compartments, among which are RNA- and protein-rich membraneless, liquid-like organelles known as biomolecular condensates. Energy-consuming processes regulate their formation…

Deterministic many-body systems governed by simple interactions can self-organize into macroscopic patterns, and the determinants of long-time behavior are assumed to be encoded in the initial configuration. Here we show that predictability…

Biological Physics · Physics 2026-04-02 Lars Koopmans , Elinor M. Kay , Hyun Youk

Bacteria commonly live in structured communities that affect human health and influence ecological systems. Heterogeneous populations, such as motile and non-motile populations, often coexist in bacteria communities. Motile subpopulations…

Biological Physics · Physics 2019-06-19 Haoran Xu , Justas Dauparas , Debasish Das , Eric Lauga , Yilin Wu