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This perspective piece is the result of a Generative Adversarial Collaboration (GAC) tackling the question `How does neural activity represent probability distributions?'. We have addressed three major obstacles to progress on answering…

Neurons and Cognition · Quantitative Biology 2024-09-05 Ralf M. Haefner , Jeff Beck , Cristina Savin , Mehrdad Salmasi , Xaq Pitkow

Studies of motor control have almost universally examined firing rates to investigate how the brain shapes behavior. In principle, however, neurons could encode information through the precise temporal patterning of their spike trains as…

Neurons and Cognition · Quantitative Biology 2014-04-15 Claire Tang , Diala Chehayeb , Kyle Srivastava , Ilya Nemenman , Samuel Sober

Several experiments and models have highlighted the importance of neuronal heterogeneity in brain dynamics and function. However, how such a cell-to-cell diversity can affect cortical computation, synchronization, and neuronal communication…

Neurons and Cognition · Quantitative Biology 2021-04-07 Katiele V. P. Brito , Fernanda Selingardi Matias

Recent studies indicate that the neurons involved in a cognitive task aren't locally limited but span out to multiple human brain regions. We obtain network components and their locations for the task of listening to music. The recorded EEG…

Neurons and Cognition · Quantitative Biology 2021-10-26 Pranav Sankhe , Ritik Madan

Cortical sensory neurons are known to be highly variable, in the sense that responses evoked by identical stimuli often change dramatically from trial to trial. The origin of this variability is uncertain, but it is usually interpreted as…

Neurons and Cognition · Quantitative Biology 2007-05-23 Gleb Basalyga , Emilio Salinas

Multistability, the coexistence of multiple attractors in a dynamical system, is explored in bursting nerve cells. A modeling study is performed to show that a large class of bursting systems, as defined by a shared topology when…

Neurons and Cognition · Quantitative Biology 2010-06-29 J. P. Newman , R. J. Butera

Credit assignment--how changes in individual neurons and synapses affect a network's output--is central to learning in brains and machines. Noise correlation, which estimates gradients by correlating perturbations of activity with changes…

Machine Learning · Computer Science 2026-01-07 Byungwoo Kang , Maceo Richards , Bernardo Sabatini

Self-sustained activity in the brain is observed in the absence of external stimuli and contributes to signal propagation, neural coding, and dynamic stability. It also plays an important role in cognitive processes. In this work, by means…

Neurons in the brain communicate with spikes, which are discrete events in time and value. Functional network models often employ rate units that are continuously coupled by analog signals. Is there a qualitative difference implied by these…

Disordered Systems and Neural Networks · Physics 2021-07-20 Christian Keup , Tobias Kühn , David Dahmen , Moritz Helias

We study the effects of coupling between layers of stochastic neural field models with laminar structure. In particular, we focus on how the propagation of waves of neural activity in each layer is affected by the coupling. Synaptic…

Pattern Formation and Solitons · Physics 2015-06-17 Zachary P. Kilpatrick

The characterisation of neuronal connectivity is one of the most important matters in neuroscience. In this work, we show that a recently proposed informational quantity, the causal mutual information, employed with an appropriate…

Neurons and Cognition · Quantitative Biology 2018-02-14 F. S. Borges , E. L. Lameu , K. C. Iarosz , P. R. Protachevicz , I. L. Caldas , R. L. Viana , E. E. N. Macau , A. M. Batista , M. S. Baptista

The investigation of the neuronal environment allows us to better understand the activity of a cerebral region as a whole. The recent experimental evidences of the presence of transporters for glutamate and GABA in both neuronal and…

Neurons and Cognition · Quantitative Biology 2015-10-07 Aurélie Garnier , Alexandre Vidal , Habib Benali

In this work we study the excitatory AMPA, and NMDA, and inhibitory GABAA receptor mediated dynamical changes in neuronal networks of neonatal rat cortex in vitro. Extracellular network-wide activity was recorded with 59 planar electrodes…

Neurons and Cognition · Quantitative Biology 2018-02-02 H. Teppola , S. Okujeni , M. -L. Linne , U. Egert

The paper examines the discrete-time dynamics of neuron models (of excitatory and inhibitory types) with piecewise linear activation functions, which are connected in a network. The properties of a pair of neurons (one excitatory and the…

chao-dyn · Physics 2007-05-23 Sitabhra Sinha

Neural development represents not only an exciting and complex field of study, with ongoing progress, but it also became the epicentre of neuroscience and developmental biology, as it strives to describe the underlying cellular and…

Neurons and Cognition · Quantitative Biology 2014-05-15 Ana M. Mihut , Graham Morgan , Marcus Kaiser

This study introduces a biologically-inspired model designed to examine the role of coincidence detection cells in speech segregation tasks. The model consists of three stages: a time-domain cochlear model that generates instantaneous rates…

Neurons and Cognition · Quantitative Biology 2024-05-13 Asaf Zorea , Miriam Furst

To compensate for sensory processing delays, the visual system must make predictions to ensure timely and appropriate behaviors. Recent work has found predictive information about the stimulus in neural populations early in vision…

Neurons and Cognition · Quantitative Biology 2018-10-05 Audrey J. Sederberg , Jason N. MacLean , Stephanie E. Palmer

Neural interactions occur on different levels and scales. It is of particular importance to understand how they are distributed among different neuroanatomical and physiological relevant brain regions. We investigated neural cross-frequency…

Adaptation and Self-Organizing Systems · Physics 2023-10-20 Dushko Lukarski , Spase Petkoski , Peng Ji , Tomislav Stankovski

Neural oscillations can enhance feature recognition, modulate interactions between neurons, and improve learning and memory. Simulational studies have shown that coherent oscillations give rise to windows in time during which information…

Neurons and Cognition · Quantitative Biology 2014-10-07 Andrew T. Sornborger , Louis Tao

Comprehending the interplay between spatial and temporal characteristics of neural dynamics can contribute to our understanding of information processing in the human brain. Graph neural networks (GNNs) provide a new possibility to…

Neurons and Cognition · Quantitative Biology 2022-04-29 Simon Wein , Alina Schüller , Ana Maria Tomé , Wilhelm M. Malloni , Mark W. Greenlee , Elmar W. Lang