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Gene regulatory networks, i.e. DNA segments in a cell which interact with each other indirectly through their RNA and protein products, lie at the heart of many important intracellular signal transduction processes. In this paper we analyse…
Distributed delays modeled by 'weak generic kernels' are introduced in the well-known coupled Landau-Stuart system, as well as a chaotic van der Pol-Rayleigh system with parametric forcing. The systems are close via the 'linear chain…
Polymerization of microtubules is ubiquitous in biological cells and under certain conditions it becomes oscillatory in time. Here simple reaction models are analyzed that capture such oscillations as well as the length distribution of…
We study the bifurcations and the chaotic behaviour of a periodically forced double-well Duffing oscillator coupled to a single-well Duffing oscillator. Using the amplitude and the frequency of the driving force as control parameters, we…
Many dynamical systems exhibit abrupt transitions or tipping as the control parameter is varied. In scenarios where the parameter is varied continuously, the rate of change of control parameter greatly affects the performance of early…
We study the weakly nonlinear saturation of the flutter instability of a planar Cosserat rod in a viscous fluid driven by a terminal follower force. This instability, established in our preceding work as a Hopf bifurcation of a…
In this paper, we consider a continuous-time model with discrete and dis-tributed delays to describe how two pieces of information interact in online social networks. Sufficient conditions are carried out to illustrate the stability of each…
Bifurcations mark qualitative changes of long-term behavior in dynamical systems and can often signal sudden ("hard") transitions or catastrophic events (divergences). Accurately locating them is critical not just for deeper understanding…
For an elastic system that is non-conservative but autonomous, subjected for example to time-independent loading by a steadily flowing fluid (air or water), a dangerous bifurcation, such as a sub-critical bifurcation, or a cyclic fold, will…
This work investigates the emergence of oscillations in one of the simplest cellular signaling networks exhibiting oscillations, namely, the dual-site phosphorylation and dephosphorylation network (futile cycle), in which the mechanism for…
A flame exhibits a limit-cycle oscillation, which is called "flame flickering" or "puffing", in a certain condition. We investigated the bifurcation structure of the flame oscillation in both simulation and experiment. We performed a…
We study bifurcations in networks of integrate-and-fire neurons with stochastic spike emission, focusing on the effects of the spatial and temporal structure of the synaptic interactions. Using a deterministic mean-field approximation of…
A four-dimensional mathematical model of the hypothalamus-pituitary-adrenal (HPA) axis is investigated, incorporating the influence of the GR concentration and general feedback functions. The inclusion of distributed time delays provides a…
In this paper, a dc-dc boost converter with sliding mode control and washout filter is analysed. This device is modelled as a three-dimensional Filippov system, characterized by the existence of sliding movement and restricted to the…
Nonsmooth formulations of physical models are common, particularly in climate modeling. However, in many of these models, there is little justification for this modeling choice, and no mathematical indication that the resulting behavior in…
In order to describe excitable reaction-diffusion systems, we derive a two-dimensional model with a Hopf and a semilocal saddle-node homoclinic bifurcation. This model gives the theoretical framework for the analysis of the saddle-node…
Experimental evidence suggests that the computational state of cortical systems change according to behavioral and stimulus context. However, it is still unknown what mechanisms underlie this adaptive processing in cortical circuitry. In…
We study a noisy oscillator with pulse delayed feedback, theoretically and in an electronic experimental implementation. Without noise, this system has multiple stable periodic regimes. We consider two types of noise: i) phase noise acting…
We analyze a class of network motifs in which a short, two-node positive feed- back motif is inserted in a three-node negative feedback loop. We demonstrate that such networks can undergo a bifurcation to a state where a stable fixed point…
Aeroelastic flutter represents a critical nonlinear instability arising from the coupling between structural elasticity and unsteady aerodynamics. In deterministic settings, flutter onset is associated with bifurcations of invariant sets…