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A diffusion-reaction model for the growth of bacterial colonies is presented. The often observed cooperative behavior developed by bacteria which increases their motility in adverse growth conditions is here introduced as a nonlinear…

Condensed Matter · Physics 2009-10-31 A. M. Lacasta , I. R. Cantalapiedra , C. E. Auguet , A. Penaranda , L. Ramirez-Piscina

Various bacterial strains (e.g. strains belonging to the genera Bacillus, Paenibacillus, Serratia and Salmonella) exhibit colonial branching patterns during growth on poor semi-solid substrates. These patterns reflect the bacterial…

Condensed Matter · Physics 2009-10-31 Yonathan Kozlovsky , Inon Cohen , Ido Golding , Eshel Ben-Jacob

In nature, microorganisms must often cope with hostile environmental conditions. To do so they have developed sophisticated cooperative behavior and intricate communication capabilities, such as: direct cell-cell physical interactions via…

Condensed Matter · Physics 2007-05-23 Eshel Ben-Jacob , Inon Cohen , Ido Golding , Yonathan Kozlovsky

Various bacterial strains exhibit colonial branching patterns during growth on poor substrates. These patterns reflect bacterial cooperative self-organization and cybernetic processes of communication, regulation and control employed during…

Condensed Matter · Physics 2015-06-25 Ido Golding , Yonathan Kozlovsky , Inon Cohen , Eshel Ben-Jacob

Bacteria are prolific at colonizing diverse surfaces under a widerange of environmental conditions, and exhibit fascinating examples of self-organization across scales. Though it has recently attracted considerable interest, the role of…

Soft Condensed Matter · Physics 2024-03-25 M. T. Khan , J. Cammann , A. Sengupta , E. Renzi , M. G. Mazza

Reaction-diffusion processes across layered media arise in several scientific domains such as pattern-forming E. coli on agar substrates, epidermal-mesenchymal coupling in development, and symmetry-breaking in cell polarisation. We develop…

Pattern Formation and Solitons · Physics 2020-09-18 Andrew L. Krause , Václav Klika , Jacob Halatek , Paul K. Grant , Thomas E. Woolley , Neil Dalchau , Eamonn A. Gaffney

In the present work we simulate the basic two-dimensional dynamics of swarming E. coli bacteria on the surface of a moderately soft agar plate. Individual bacteria are modelled by self-propelled ridged bodies (agents), which interact with…

Soft Condensed Matter · Physics 2016-12-31 David Hansmann , Guido Fier , Rubén Carlos Buceta

Starting from a particle model we derive a macroscopic aggregation-diffusion equation for the evolution of slime mold under the assumption of propagation of chaos in the large particle limit. We analyze properties of the macroscopic model…

Adaptation and Self-Organizing Systems · Physics 2020-06-09 Simone Göttlich , Stephen Knapp , Dylan Weber

We study the migration of chemotactic wild-type Escherichia coli populations in semisolid (soft) agar in the concentration range C = 0.15-0.5% (w/v). For C < 0.35%, expanding bacterial colonies display characteristic chemotactic rings. At C…

Soft Condensed Matter · Physics 2011-08-09 O. A. Croze , G. P. Ferguson , M. E. Cates , W. C. K. Poon

This paper introduces a reaction-diffusion-chemotaxis model for bacterial aggregation patterns on the surface of thin agar plates. It is based on the non-linear degenerate cross diffusion model proposed by Kawasaki et al. (J. of Theor.…

Cell Behavior · Quantitative Biology 2013-01-23 J. Francisco Leyva , Carlos Malaga , Ramon G. Plaza

In E. coli, accurate cell division depends upon the oscillation of Min proteins from pole to pole. We provide a model for the polar localization of MinD based only on diffusion, a delay for nucleotide exchange, and different rates of…

Subcellular Processes · Quantitative Biology 2009-11-10 Rahul V. Kulkarni , Kerwyn Casey Huang , Morten Kloster , Ned S. Wingreen

The bacterium E.Coli swims in a zig-zag manner, in a series of straight runs and tumbles occurring alternately, with the run-durations dependent on the local spatial gradient of chemo-attractants/repellants. This enables the organism to…

Cell Behavior · Quantitative Biology 2008-12-31 Melissa Reneaux , Manoj Gopalakrishnan

Motile eukaryotic cells display distinct modes of migration that often occur within the same cell type. It remains unclear, however, whether transitions between the migratory modes require changes in external conditions, or whether the…

Pattern Formation and Solitons · Physics 2025-05-29 Jack M. Hughes , Cristina Martinez-Torres , Carsten Beta , Leah Edelstein-Keshet , Arik Yochelis

Reaction-diffusion equations describe various spatially extended processes that unfold as traveling fronts moving at constant velocity. We introduce and solve analytically a model that, besides such fronts, supports solutions advancing as…

Biological Physics · Physics 2026-02-13 Louis Brezin , Kyle J. Shaffer , Kirill S. Korolev

To model the morphogenesis of rod-shaped bacterial micro-colony, several individual-based models have been proposed in the biophysical literature. When studying the shape of micro-colonies, most models present interaction forces such as…

Cell Behavior · Quantitative Biology 2020-08-12 Marie Doumic , Sophie Hecht , Diane Peurichard

We study the Schloegl model in a vesicle with semi-permeable membrane. The diffusion constant takes a smaller value in the membrane region, which prevents the outflow of self-catalytic product. A nonequilibrium state is stably maintained…

Statistical Mechanics · Physics 2009-11-11 Hidetsugu Sakaguchi

Colonies of bacteria endowed with a pili-based self-propulsion machinery are ideal models for investigating the structure and dynamics of active many-particle systems. We study Neisseria gonorrhoeae colonies with a molecular-dynamics-based…

Soft Condensed Matter · Physics 2022-10-18 Kai Zhou , Marc Hennes , Berenike Maier , Gerhard Gompper , Benedikt Sabass

A multicomponent multiphase reactive transport simulator has been developed to facilitate the investigation of a large variety of phenomena in porous media including component transport, diffusion, microbiological growth and decay, cell…

Computational Engineering, Finance, and Science · Computer Science 2014-10-24 Pavel Hron , Daniel Jost , Peter Bastian , Claudia Gallert , Josef Winter , Olaf Ippisch

The reaction-diffusion models have been extensively applied to explain the mechanism of pattern formations in early embryogenesis based on geometrically confined microtissues consisting of human pluripotent stem cells. Recently, mechanical…

Biological Physics · Physics 2022-11-22 Tiankai Zhao , Hongyan Yuan

Motile bacteria can migrate along chemical gradients in a process known as chemotaxis. When exposed to uniform environmental stress, Escherichia coli cells coordinate their chemotactic responses to form millimeter-sized condensates…

Biological Physics · Physics 2025-05-02 Nir Livne , Ady Vaknin , Oded Agam
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