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This short paper presents an abstract, tunable model of genomic structural change within the cell lifecycle and explores its use with simulated evolution. A well-known Boolean model of genetic regulatory networks is extended to include…

Computational Engineering, Finance, and Science · Computer Science 2012-01-18 Larry Bull

The study of the response of complex dynamical social, biological, or technological networks to external perturbations has numerous applications. Random Boolean Networks (RBNs) are commonly used a simple generic model for certain dynamics…

Disordered Systems and Neural Networks · Physics 2009-04-29 Qiming Lu , Christof Teuscher

Randomized Neural Networks explore the behavior of neural systems where the majority of connections are fixed, either in a stochastic or a deterministic fashion. Typical examples of such systems consist of multi-layered neural network…

Machine Learning · Computer Science 2021-02-03 Claudio Gallicchio , Simone Scardapane

Despite their apparent simplicity, random Boolean networks display a rich variety of dynamical behaviors. Much work has been focused on the properties and abundance of attractors. The topologies of random Boolean networks with one input per…

Disordered Systems and Neural Networks · Physics 2009-11-11 Björn Samuelsson , Carl Troein

Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks. It has been observed that many published models of such networks are defined by…

Molecular Networks · Quantitative Biology 2019-12-06 Elijah Paul , Gleb Pogudin , William Qin , Reinhard Laubenbacher

Recurrent neural networks (RNNs) are widely used throughout neuroscience as models of local neural activity. Many properties of single RNNs are well characterized theoretically, but experimental neuroscience has moved in the direction of…

Machine Learning · Computer Science 2023-01-31 Leo Kozachkov , Michaela Ennis , Jean-Jacques Slotine

Independent of the technology, it is generally expected that future nanoscale devices will be built from vast numbers of densely arranged devices that exhibit high failure rates. Other than that, there is little consensus on what type of…

Hardware Architecture · Computer Science 2016-11-17 Christof Teuscher , Natali Gulbahce , Thimo Rohlf

Random Boolean networks (RBNs) are frequently employed for modelling complex systems driven by information processing, e.g. for gene regulatory networks (GRNs). Here we propose a hierarchical adaptive RBN (HARBN) as a system consisting of…

Physics and Society · Physics 2016-03-23 Piotr J. Gorski , Agnieszka Czaplicka , Janusz A. Holyst

We define and study a few properties of a class of random automata networks. While regular finite one-dimensional cellular automata are defined on periodic lattices, these automata networks, called randomized cellular automata, are defined…

Cellular Automata and Lattice Gases · Physics 2009-11-13 Nino Boccara

Artificial neural networks (ANNs) are essential tools in machine learning that have drawn increasing attention in neuroscience. Besides offering powerful techniques for data analysis, ANNs provide a new approach for neuroscientists to build…

Neurons and Cognition · Quantitative Biology 2020-09-25 Guangyu Robert Yang , Xiao-Jing Wang

Boolean networks are a valuable class of discrete dynamical systems models, but they remain fundamentally limited by their inability to capture multi-way interactions in their components. To remedy this limitation, we propose a model of…

Dynamical Systems · Mathematics 2024-09-02 Kevin M. Stoltz , Cliff A. Joslyn

Genetic Regulatory Networks (GRNs) plays a vital role in the understanding of complex biological processes. Modeling GRNs is significantly important in order to reveal fundamental cellular processes, examine gene functions and understanding…

Computational Engineering, Finance, and Science · Computer Science 2012-05-10 Khalid Raza , Rafat Parveen

Improving the efficiency of current neural networks and modeling them in biological neural systems have become popular research directions in recent years. Pulse-coupled neural network (PCNN) is a well applicated model for imitating the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Haoran Liu , Mingzhe Liu , Peng Li , Jiahui Wu , Xin Jiang , Zhuo Zuo , Bingqi Liu

Traditional machine learning excels on static benchmarks, but the real world is dynamic and seldom as carefully curated as test sets. Practical applications may generally encounter undesired inputs, are required to deal with novel…

Machine Learning · Computer Science 2025-03-17 Roshni . R. Kamath , Rupert Mitchell , Subarnaduti Paul , Kristian Kersting , Martin Mundt

The editing of transcribed RNA by other molecules such that the form of the final product differs from that specified in the corresponding DNA sequence is ubiquitous. This paper uses an abstract, tunable Boolean genetic regulatory network…

Neural and Evolutionary Computing · Computer Science 2015-05-11 Larry Bull

The scope of this teaching package is to make a brief induction to Artificial Neural Networks (ANNs) for people who have no previous knowledge of them. We first make a brief introduction to models of networks, for then describing in general…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Carlos Gershenson

The random neural network (RNN) is a mathematical model for an "integrate and fire" spiking network that closely resembles the stochastic behaviour of neurons in mammalian brains. Since its proposal in 1989, there have been numerous…

Neural and Evolutionary Computing · Computer Science 2018-10-23 Yonghua Yin

Restricted Boltzmann Machines are simple yet powerful neural networks. They can be used for learning structure in data, and are used as a building block of more complex neural architectures. At the same time, their simplicity makes them…

Disordered Systems and Neural Networks · Physics 2025-01-09 Giovanni di Sarra , Barbara Bravi , Yasser Roudi

Recurrent neural networks (RNNs) are widely used in computational neuroscience and machine learning applications. In an RNN, each neuron computes its output as a nonlinear function of its integrated input. While the importance of RNNs,…

Neurons and Cognition · Quantitative Biology 2012-07-10 Sebastian Bitzer , Stefan J. Kiebel

Boolean networks, first developed in the late 1960s as a tool for studying complex disordered dynamical systems, consist of nodes governed by Boolean functions whose evolution is entirely deterministic in that the state of the network at a…

Quantum Physics · Physics 2023-03-02 Ian T. Durham