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A variant of Kauffman's model of cellular metabolism is presented. It is a randomly generated network of boolean gates, identical to Kauffman's except for a small bias in favor of boolean gates that depend on at most one input. The bias is…

adap-org · Physics 2009-10-22 James F. Lynch

Boolean Networks have been used to study numerous phenomena, including gene regulation, neural networks, social interactions, and biological evolution. Here, we propose a general method for determining the critical behavior of Boolean…

Disordered Systems and Neural Networks · Physics 2009-11-11 Andre A. Moreira , Luis A. N. Amaral

This is the second paper of a series of two about the structural properties that influence the asymptotic dynamics of Random Boolean Networks. Here we study the functionally independent clusters in which the relevant elements, introduced…

Disordered Systems and Neural Networks · Physics 2009-10-30 U. Bastolla , G. Parisi

Random Boolean networks were introduced in 1969 by Kauffman as a model for gene regulation. By combining analytical arguments and efficient numerical simulations, we evaluate the properties of relevant components of critical random Boolean…

Disordered Systems and Neural Networks · Physics 2009-11-11 V. Kaufman , B. Drossel

Boolean variables are such that they take only values on $ \mathbb{Z}_2 \cong \left\{0, 1 \right\} $. \textit{NK}-Kauffman networks are dynamical deterministic systems of $ N $ Boolean functions that depend only on $ K \leq N $ Boolean…

Adaptation and Self-Organizing Systems · Physics 2014-04-14 Federico Zertuche

Boolean threshold networks have recently been proposed as useful tools to model the dynamics of genetic regulatory networks, and have been successfully applied to describe the cell cycles of \textit{S. cerevisiae} and \textit{S. pombe}.…

Chaotic Dynamics · Physics 2010-11-18 Jorge G. T. Zañudo , Maximino Aldana , Gustavo Martínez-Mekler

In this work we consider random Boolean networks that provide a general model for genetic regulatory networks. We extend the analysis of James Lynch who was able to proof Kauffman's conjecture that in the ordered phase of random networks,…

Cellular Automata and Lattice Gases · Physics 2007-05-23 Steffen Schober , Martin Bossert

We investigate Threshold Random Boolean Networks with $K = 2$ inputs per node, which are equivalent to Kauffman networks, with only part of the canalyzing functions as update functions. According to the simplest consideration these networks…

Disordered Systems and Neural Networks · Physics 2007-07-16 Florian Greil , Barbara Drossel

This review explains in a self-contained way the properties of random Boolean networks and their attractors, with a special focus on critical networks. Using small example networks, analytical calculations, phenomenological arguments, and…

Statistical Mechanics · Physics 2008-11-14 Barbara Drossel

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Dynamical Systems · Mathematics 2015-02-26 Marco Villani , Davide Campioli , Chiara Damiani , Andrea Roli , Alessandro Filisetti , Roberto Serra

This is the first of two papers about the structure of Kauffman networks. In this paper we define the relevant elements of random networks of automata, following previous work by Flyvbjerg and Flyvbjerg and Kjaer, and we study numerically…

Disordered Systems and Neural Networks · Physics 2009-10-30 U. Bastolla , G. Parisi

The complex dynamics of gene expression in living cells can be well-approximated using Boolean networks. The average sensitivity is a natural measure of stability in these systems: values below one indicate typically stable dynamics…

Molecular Networks · Quantitative Biology 2018-10-03 Bryan C. Daniels , Hyunju Kim , Douglas Moore , Siyu Zhou , Harrison Smith , Bradley Karas , Stuart A. Kauffman , Sara I. Walker

The concept of control is crucial for effectively understanding and applying biological network models. Key structural features relate to control functions through gene regulation, signaling, or metabolic mechanisms, and computational…

Molecular Networks · Quantitative Biology 2024-11-05 David Murrugarra , Alan Veliz-Cuba , Elena Dimitrova , Claus Kadelka , Matthew Wheeler , Reinhard Laubenbacher

We present a rigorous mathematical framework for analyzing dynamics of a broad class of Boolean network models. We use this framework to provide the first formal proof of many of the standard critical transition results in Boolean network…

Disordered Systems and Neural Networks · Physics 2016-08-30 C. Seshadhri , Yevgeniy Vorobeychik , Jackson R. Mayo , Robert C. Armstrong , Joseph R. Ruthruff

Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions (from molecules in gene regulatory…

Molecular Networks · Quantitative Biology 2023-10-20 Jordan C. Rozum , Colin Campbell , Eli Newby , Fatemeh Sadat Fatemi Nasrollahi , Reka Albert

Random Boolean Network has been used to find out regulation patterns of genes in organism. his approach is very interesting to use in a game such as N Person PD. Here we assume that action is influenced by input in the form of choices of…

Disordered Systems and Neural Networks · Physics 2007-05-23 Hokky Situngkir , Deni Khanafiah

The critical boundaries separating ordered from chaotic behavior in randomly wired S-state networks are calculated. These networks are a natural generalization of random Boolean nets and are proposed as on extended approach to genetic…

adap-org · Physics 2007-05-23 Ricard V. Sole , Bartolo Luque , Stuart Kauffman

Standard Random Boolean Networks display an order-disorder phase transition. We add to the standard Random Boolean Networks a disconnection rule which couples the control and order parameters. By this way, the system is driven to the…

Disordered Systems and Neural Networks · Physics 2009-11-07 Bartolo Luque , Fernando J. Ballesteros , Enrique M. Muro

Random graphs have played an instrumental role in modelling real-world networks arising from the internet topology, social networks, or even protein-interaction networks within cells. Percolation, on the other hand, has been the fundamental…

Probability · Mathematics 2018-09-12 Souvik Dhara

We investigate analytically and numerically the critical line in undirected random Boolean networks with arbitrary degree distributions, including scale-free topology of connections $P(k)\sim k^{-\gamma}$. We show that in infinite…

Disordered Systems and Neural Networks · Physics 2013-05-29 Piotr Fronczak , Agata Fronczak , Janusz A. Holyst
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