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Related papers: Origin of complexity in multicellular organisms

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The spatial character of territorial systems plays a crucial role in the emergence of their complexities. This contribution aims at illustrating to what extent different types of complexities can be exhibited in models of such systems. We…

Physics and Society · Physics 2019-01-29 Juste Raimbault

Current analyses of genomes from numerous species show that the diversity of organism's functional and behavioral characters is not proportional to the number of genes that encode the organism. We investigate the hypothesis that the…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Olof Goernerup , James P. Crutchfield

Even when concepts similar to emergence have been used since antiquity, we lack an agreed definition. However, emergence has been identified as one of the main features of complex systems. Most would agree on the statement ``life is…

General Physics · Physics 2025-12-22 Carlos Gershenson

Species or population that proliferate faster than others become dominant in numbers. Catalysis allows catalytic sets within a molecular reaction network to dominate the non catalytic parts of the network by processing most of the available…

Cell Behavior · Quantitative Biology 2016-08-31 Rudolf Hanel

The reproduction of a living cell requires a repeatable set of chemical events to be properly coordinated. Such events define a replication cycle, coupling the growth and shape change of the cell membrane with internal metabolic reactions.…

Cell Behavior · Quantitative Biology 2007-05-23 J. Macia , R. V. Sole

Systems of dynamical interactions between competing species can be used to model many complex systems, and can be mathematically described by {\em random} networks. Understanding how patterns of activity arise in such systems is important…

Adaptation and Self-Organizing Systems · Physics 2016-01-21 Nick McCullen , Thomas Wagenknecht

We construct a simple model of a proto-cell that simulates a stochastic dynamics of abstract chemicals on a two-dimensional lattice. We assume that chemicals catalyze their reproduction through interaction with each other, and that between…

adap-org · Physics 2007-05-23 Naoaki Ono , Takashi Ikegami

The well-defined but intricate course of time evolution exhibited by many naturally occurring phenomena suggests some source of dynamic order sustaining it. In spite of its obviousness as a problem, it has remained absent from the…

Adaptation and Self-Organizing Systems · Physics 2021-03-02 R. Herrero , J. Farjas , F. Pi , G. Orriols

Continuing generation of novelty, complexity, and adaptation are well-established as core aspects of open-ended evolution. However, it has yet to be firmly established to what extent these phenomena are coupled and by what means they…

Neural and Evolutionary Computing · Computer Science 2025-09-05 Matthew Andres Moreno , Santiago Rodriguez Papa , Charles Ofria

Biological systems, from a cell to the human brain, are inherently complex. A powerful representation of such systems, described by an intricate web of relationships across multiple scales, is provided by complex networks. Recently, several…

Quantitative Methods · Quantitative Biology 2018-02-06 M. De Domenico

The network concept is increasingly used for the description of complex systems. Here we summarize key aspects of the evolvability and robustness of the hierarchical network-set of macromolecules, cells, organisms, and ecosystems. Listing…

Molecular Networks · Quantitative Biology 2010-10-05 Huba J. M. Kiss , Agoston Mihalik , Tibor Nanasi , Balint Ory , Zoltan Spiro , Csaba Soti , Peter Csermely

This paper presents a real-time simulation involving ''protozoan-like'' cells that evolve by natural selection in a physical 2D ecosystem. Selection pressure is exerted via the requirements to collect mass and energy from the surroundings…

Neural and Evolutionary Computing · Computer Science 2023-05-23 Dylan Cope

We propose a principle of consistency between different hierarchical levels of biological systems. Given a consistency between molecule replication and cell reproduction, universal statistical laws on cellular chemical abundances are…

Cell Behavior · Quantitative Biology 2008-07-21 Kunihiko Kaneko , Chikara Furusawa

Phenotypic variation is a hallmark of cellular physiology. Metabolic heterogeneity, in particular, underpins single-cell phenomena such as microbial drug tolerance and growth variability. Much research has focussed on transcriptomic and…

Molecular Networks · Quantitative Biology 2019-01-31 Mona K. Tonn , Philipp Thomas , Mauricio Barahona , Diego A Oyarzún

Metabolism displays striking and robust regularities in the forms of modularity and hierarchy, whose composition may be compactly described. This renders metabolic architecture comprehensible as a system, and suggests the order in which…

Molecular Networks · Quantitative Biology 2015-06-05 Rogier Braakman , Eric Smith

Living organisms have some common structures, chemical reactions and molecular structures. The organisms consist of cells with cell division, they have homochirality of protein and carbohydrate units, and metabolism, and genetics, and they…

Populations and Evolution · Quantitative Biology 2025-05-27 Søren Toxvaerd

When a large number of similar entities interact among each other and with their environment at a low scale, unexpected outcomes at higher spatio-temporal scales might spontaneously arise. This nontrivial phenomenon, known as emergence,…

Physics and Society · Physics 2022-05-25 Oriol Artime , Manlio De Domenico

Inside every living cell is the cytoplasm: a fluid mixture of thousands of different macromolecules, predominantly proteins. This mixture is where most of the biochemistry occurs that enables living cells to function, and it is perhaps the…

Soft Condensed Matter · Physics 2009-11-11 Richard P. Sear

We study the dynamics of proliferating cell collectives whose microscopic constituents' growth is inhibited by macroscopic growth-induced stress. Discrete particle simulations of a growing collective show the emergence of concentric-ring…

Biological Physics · Physics 2024-05-17 Scott Weady , Bryce Palmer , Adam Lamson , Taeyoon Kim , Reza Farhadifar , Michael J. Shelley

Complex macroscopic behaviour can arise in many-body systems with only very simple elements as a consequence of the combination of competition and inhomogeneity. This paper attempts to illustrate how statistical physics has driven this…

Disordered Systems and Neural Networks · Physics 2012-01-10 David Sherrington
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