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It has recently been suggested that evolution exploits a form of fitness landscape smoothing within eukaryotic sex due to the haploid-diploid cycle. This short paper presents a simple modification to the standard evolutionary computing…

Neural and Evolutionary Computing · Computer Science 2019-03-29 Larry Bull

Background: Recent experimental and theoretical studies have shown that small asexual populations evolving on complex fitness landscapes may achieve a higher fitness than large ones due to the increased heterogeneity of adaptive…

Populations and Evolution · Quantitative Biology 2011-07-12 Kavita Jain , Joachim Krug , Su-Chan Park

Understanding the influence of an environment on the evolution of its resident population is a major challenge in evolutionary biology. Great progress has been made in homogeneous population structures while heterogeneous structures have…

Populations and Evolution · Quantitative Biology 2014-07-30 Wes Maciejewski , Gregory J. Puleo

Experimental studies on enzyme evolution show that only a small fraction of all possible mutation trajectories are accessible to evolution. However, these experiments deal with individual enzymes and explore a tiny part of the fitness…

Populations and Evolution · Quantitative Biology 2015-05-30 Alexander E. Lobkovsky , Yuri I. Wolf , Eugene V. Koonin

We study the evolution of recombination using a microscopic model developed within the frame of the theory of quantitative traits. Two components of fitness are considered: a static one that describes adaptation to environmental factors not…

Populations and Evolution · Quantitative Biology 2007-05-23 Franco Bagnoli , Carlo Guardiani

Intransitivity is supposed to be a main reason for deficits in coevolutionary progress and inheritable superiority. Besides, coevolutionary dynamics is characterized by interactions yielding subjective fitness, but aiming at solutions that…

Neural and Evolutionary Computing · Computer Science 2016-11-30 Hendrik Richter

The factors that influence genetic architecture shape the structure of the fitness landscape, and therefore play a large role in the evolutionary dynamics. Here the NK model is used to investigate how epistasis and pleiotropy -- key…

Populations and Evolution · Quantitative Biology 2013-04-16 Bjørn Østman

Within the framework of population genetics we consider the evolution of an asexual haploid population under the effect of a rapidly varying natural selection (microevolution). We focus on the case in which the environment exerting…

Populations and Evolution · Quantitative Biology 2015-06-22 Stefano Bo , Andrea Mazzolini , Antonio Celani

We investigate the evolutionary dynamics of a finite population of sequences adapting to NK fitness landscapes. We find that, unlike in the case of an infinite population, the average fitness in a finite population is maximized at a small…

Biological Physics · Physics 2009-11-07 Paulo R. A. Campos , Christoph Adami , Claus O. Wilke

The fitness landscape metaphor plays a central role on the modeling of optimizing principles in many research fields, ranging from evolutionary biology, where it was first introduced, to management research. Here we consider the ensemble of…

Populations and Evolution · Quantitative Biology 2019-01-30 Paulo R. A. Campos , José F. Fontanari

We analyze the population dynamics of a broad class of fitness functions that exhibit epochal evolution---a dynamical behavior, commonly observed in both natural and artificial evolutionary processes, in which long periods of stasis in an…

adap-org · Physics 2007-05-23 James P. Crutchfield , Erik van Nimwegen

In epistatic fitness landscapes, the fitness effect of a mutation depends on the genetic background and may even switch between deleterious and beneficial depending on the presence of another mutation. Epistatic interactions may cause both…

A simplified form of the time dependent evolutionary dynamics of a quasispecies model with a rugged fitness landscape is solved via a mapping onto a random flux model whose asymptotic behavior can be described in terms of a random walk. The…

Statistical Mechanics · Physics 2009-11-11 Clement Sire , Satya N. Majumdar , David S. Dean

Biological systems are modular, and this modularity affects the evolution of biological systems over time and in different environments. We here develop a theory for the dynamics of evolution in a rugged, modular fitness landscape. We show…

Populations and Evolution · Quantitative Biology 2015-06-23 Jeong-Man Park , Man Chen , Dong Wang , Michael W. Deem

This Letter studies the quasispecies dynamics of a population capable of genetic repair evolving on a time-dependent fitness landscape. We develop a model that considers an asexual population of single-stranded, conservatively replicating…

Populations and Evolution · Quantitative Biology 2009-11-13 Pavel Gorodetsky , Emmanuel Tannenbaum

We present a mathematical simplification for the evolutionary dynamics of a heritable trait within a two-sex population. This trait is assumed to control the timing of sex-specific life-history events, such as the age of sexual maturity and…

Populations and Evolution · Quantitative Biology 2019-07-04 M. H. Chan , K. Hawkes , P. S. Kim

We consider a stochastic individual-based model of adaptive dynamics for an asexually reproducing population with mutation. Biologically motivated by the influence of seasons or the variation of drug concentration during medical treatment,…

Probability · Mathematics 2025-03-26 Manuel Esser , Anna Kraut

Fitness landscapes are genotype to fitness mappings commonly used in evolutionary biology and computer science which are closely related to spin glass models. In this paper, we study the NK model for fitness landscapes where the interaction…

Populations and Evolution · Quantitative Biology 2015-06-12 Stefan Nowak , Joachim Krug

The nature of epistasis has important consequences for the evolutionary significance of sex and recombination. Recent efforts to find negative epistasis as source of negative linkage disequilibrium and associated long-term sex advantage…

Populations and Evolution · Quantitative Biology 2009-10-02 J. Arjan G. M. de Visser , Su-Chan Park , Joachim Krug

We study the evolution of large but finite asexual populations evolving in fitness landscapes in which all mutations are either neutral or strongly deleterious. We demonstrate that despite the absence of higher fitness genotypes, adaptation…

Biological Physics · Physics 2007-05-23 Claus O. Wilke