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A molecule's geometry, also known as conformation, is one of a molecule's most important properties, determining the reactions it participates in, the bonds it forms, and the interactions it has with other molecules. Conventional…

Machine Learning · Computer Science 2020-01-01 Elman Mansimov , Omar Mahmood , Seokho Kang , Kyunghyun Cho

Finding the best configuration of algorithms' hyperparameters for a given optimization problem is an important task in evolutionary computation. We compare in this work the results of four different hyperparameter tuning approaches for a…

Neural and Evolutionary Computing · Computer Science 2022-03-18 Furong Ye , Carola Doerr , Hao Wang , Thomas Bäck

The simple genetic algorithm is proposed for the simulation of quantum many body dynamics. It uses the selection of entangled quantum states and has the inbuilt absolute decoherence that comes from the limitation of classical memory. It…

Quantum Physics · Physics 2008-01-24 Yuri Ozhigov

It has been widely recognized that the performance of a multi-agent system is highly affected by its organization. A large scale system may have billions of possible ways of organization, which makes it impractical to find an optimal choice…

Multiagent Systems · Computer Science 2014-11-25 Zhiqi Shen , Ling Yu , Han Yu

The community structure of a complex network can be determined by finding the partitioning of its nodes that maximizes modularity. Many of the proposed algorithms for doing this work by recursively bisecting the network. We show that this…

Computers and Society · Computer Science 2015-05-13 Yudong Sun , Bogdan Danila , Kresimir Josic , Kevin E. Bassler

In this paper, we study the construction of structural models for the description of substitutional defects in crystalline materials. Predicting and designing the atomic structures in such systems is highly challenging due to the…

Computational Physics · Physics 2025-07-04 Xiaoxu Li , Ge Xu , Huajie Chen , Xingyu Gao , Haifeng Song

Molecular Mechanics describes molecules as particle configurations interacting via classical potentials. These {\it configurational energies} usually consist of the sum of different phenomenological terms which are tailored to the…

Materials Science · Physics 2017-01-11 Manuel Friedrich , Paolo Piovano , Ulisse Stefanelli

With the recent advances in machine learning for quantum chemistry, it is now possible to predict the chemical properties of compounds and to generate novel molecules. Existing generative models mostly use a string- or graph-based…

Biomolecules · Quantitative Biology 2020-10-14 Vitali Nesterov , Mario Wieser , Volker Roth

In early-stage architectural design, optimization algorithms are essential for efficiently exploring large and complex design spaces under tight computational constraints. While prior research has benchmarked various optimization methods,…

Neural and Evolutionary Computing · Computer Science 2025-04-14 Farnaz Nazari , Wei Yan

The problem of fast items retrieval from a fixed collection is often encountered in most computer science areas, from operating system components to databases and user interfaces. We present an approach based on hash tables that focuses on…

Neural and Evolutionary Computing · Computer Science 2020-07-17 Dan Domnita , Ciprian Oprisa

We present a universal method for the large-scale prediction of the atomic structure of clusters. Our algorithm performs the joint evolutionary search for all clusters in a given area of the compositional space and takes advantage of…

Materials Science · Physics 2018-12-18 S. V. Lepeshkin , V. S. Baturin , Yu. A. Uspenskii , Artem R. Oganov

Modelling and understanding properties of materials from first principles require knowledge of the underlying atomistic structure. This entails knowing the individual identity and position of all involved atoms. Obtaining such information…

Chemical Physics · Physics 2023-07-06 Mads-Peter Verner Christiansen , Nikolaj Rønne , Bjørk Hammer

In this paper, we have to concentrate on implementation of Weighted Clustering Algorithm with the help of Genetic Algorithm (GA).Here we have developed new algorithm for the implementation of GA-based approach with the help of Weighted…

Networking and Internet Architecture · Computer Science 2010-02-11 Bhaskar Nandi , Subhabrata Barman , Soumen Paul

Personalized medicine is expected to maximize the intended drug effects and minimize side effects by treating patients based on their genetic profiles. Thus, it is important to generate drugs based on the genetic profiles of diseases,…

Machine Learning · Computer Science 2021-12-17 Sejin Park , Hyunju Lee

We reformulate the problem of modularity maximization over the set of partitions of a network as a conic optimization problem over the completely positive cone, converting it from a combinatorial optimization problem to a convex continuous…

Data Analysis, Statistics and Probability · Physics 2008-12-18 Roland Hildebrand

We describe a dynamic programming algorithm for predicting optimal RNA secondary structure, including pseudoknots. The algorithm has a worst case complexity of ${\cal O}(N^6)$ in time and ${\cal O}(N^4)$ in storage. The description of the…

Biological Physics · Physics 2009-09-25 Elena Rivas , Sean R. Eddy

Modelling and predicting protein configurations is crucial for advancing drug discovery, enabling the design of treatments for life-threatening diseases. A critical aspect of this challenge is rotamer optimisation - the determination of…

Quantum Physics · Physics 2025-07-28 Anastasia Agathangelou , Dilhan Manawadu , Ivano Tavernelli

In this paper we analyse capabilities of eclipse mapping technique, based on genetic algorithm optimization. To model of accretion disk we used the "fire-flies" conception. This model allows us to reconstruct the distribution of radiating…

Astrophysics · Physics 2008-01-22 A. V. Halevin

This paper presents a new type of genetic algorithm for the set covering problem. It differs from previous evolutionary approaches first because it is an indirect algorithm, i.e. the actual solutions are found by an external decoder…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin

In this paper, a genetic algorithm, one of the evolutionary algorithms optimization methods, is used for the first time for the problem of finding extremal binary self-dual codes. We present a comparison of the computational times between a…

Neural and Evolutionary Computing · Computer Science 2020-12-23 Adrian Korban , Serap Sahinkaya , Deniz Ustun