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Understanding age-group dynamics of infectious diseases is a fundamental issue for both scientific study and policymaking. Age-structure epidemic models were developed in order to study and improve our understanding of these dynamics. By…

Populations and Evolution · Quantitative Biology 2019-11-22 Rami Yaari , Amit Huppert , Itai Dattner

Epidemiology characterizes the influence of causes to disease and health conditions of defined populations. Cohort studies are population-based studies involving usually large numbers of randomly selected individuals and comprising numerous…

Computer Vision and Pattern Recognition · Computer Science 2015-01-19 Bernhard Preim , Paul Klemm , Helwig Hauser , Katrin Hegenscheid , Steffen Oeltze , Klaus Toennies , Henry Völzke

In the context of bacteria and models of their evolution under genome rearrangement, we explore a novel application of group representation theory to the inference of evolutionary history. Our contribution is to show, in a very general…

Populations and Evolution · Quantitative Biology 2017-08-02 Jeremy G Sumner , Peter D Jarvis , Andrew R Francis

Understanding how vaccines perform against different pathogen genotypes is crucial for developing effective prevention strategies, particularly for highly genetically diverse pathogens like HIV. Sieve analysis is a statistical framework…

Methodology · Statistics 2025-12-11 James Peng , Michal Juraska , Pamela A. Shaw , Peter B. Gilbert

How to allocate vaccines over heterogeneous individuals is one of the important policy decisions in pandemic times. This paper develops a procedure to estimate an individualized vaccine allocation policy under limited supply, exploiting…

Econometrics · Economics 2021-10-25 Toru Kitagawa , Guanyi Wang

Estimating prevalence, the fraction of a population with a certain medical condition, is fundamental to epidemiology. Traditional methods rely on classification of test samples taken at random from a population. Such approaches to…

Methodology · Statistics 2022-03-25 Paul Patrone , Anthony Kearsley

We present an algorithm for the numerical evaluation of the state-space distribution of an Age-of-Information network. Given enough computational resources, the evaluation can be performed to an arbitrary high precision. An…

Systems and Control · Electrical Eng. & Systems 2022-06-14 Richard Schoeffauer , Gerhard Wunder

The envelope theory, also known as the auxiliary field method, is a simple technique to compute approximate solutions of Hamiltonians for $N$ identical particles in $D$-dimension. The accuracy of this method is tested by computing the…

Quantum Physics · Physics 2015-05-19 Claude Semay

When using multiple data sources in an analysis, it is important to understand the influence of each data source on the analysis and the consistency of the data sources with each other and the model. We suggest the use of a retrospective…

Applications · Statistics 2020-09-08 Jacob Parsons , Xiaoyue Niu , Le Bao

We review vaccine efficacy (VE) estimands for susceptibility in individual randomized trials with natural (unmeasured) exposure, where individual responses are measured as time from vaccination until an event (e.g., disease from the…

Methodology · Statistics 2026-01-27 Michael P. Fay , Dean Follmann , Bruce J. Swihart , Lauren E. Dang

Mathematical models are increasing adopted for setting targets for disease prevention and control. As model-informed policies are implemented, however, the inaccuracies of some forecasts become apparent, for example overprediction of…

Approximate Bayesian computation (ABC) have become a essential tool for the analysis of complex stochastic models. Earlier, Grelaud et al. (2009) advocated the use of ABC for Bayesian model choice in the specific case of Gibbs random…

Methodology · Statistics 2015-03-19 Christian P. Robert , Jean-Marie Cornuet , Jean-Michel Marin , Natesh Pillai

Bayesian inference affords scientists with powerful tools for testing hypotheses. One of these tools is the Bayes factor, which indexes the extent to which support for one hypothesis over another is updated after seeing the data. Part of…

Computation · Statistics 2018-12-11 Thomas J. Faulkenberry

Envelope model also known as multivariate regression model was proposed to solve the multiple response regression problems. It measures the linear association between predictors and multiple responses by using the minimal reducing subspace…

Methodology · Statistics 2018-05-07 Bochao Jia

Wearing a mask is a strong protection against the COVID-19 pandemic, even though the vaccine has been successfully developed and is widely available. However, many people wear them incorrectly. This observation prompts us to devise an…

Computer Vision and Pattern Recognition · Computer Science 2021-08-25 Yixin Hu , Xingyu Li

We use machine learning to provide a tractable measure of the amount of predictable variation in the data that a theory captures, which we call its "completeness." We apply this measure to three problems: assigning certain equivalents to…

Theoretical Economics · Economics 2019-10-17 Drew Fudenberg , Jon Kleinberg , Annie Liang , Sendhil Mullainathan

We develop and apply two calibration procedures for checking the coverage of approximate Bayesian credible sets including intervals estimated using Monte Carlo methods. The user has an ideal prior and likelihood, but generates a credible…

Computation · Statistics 2026-05-19 Jeong Eun Lee , Geoff K. Nicholls , Robin J. Ryder

Some aspects of Computer Algebra (notably Computation Group Theory and Computational Number Theory) have some good databases of examples, typically of the form "all the X up to size n". But most of the others, especially on the polynomial…

Symbolic Computation · Computer Science 2022-10-31 James Harold Davenport

The features in high dimensional biomedical prediction problems are often well described with lower dimensional manifolds. An example is genes that are organised in smaller functional networks. The outcome can then be described with the…

Gender representation in mass media has long been mainly studied by qualitatively analyzing content. This article illustrates how automated computational methods may be used in this context to scale up such empirical observations and…

Computers and Society · Computer Science 2021-05-13 Antoine Mazieres , Telmo Menezes , Camille Roth