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A fundamental approach in neuroscience research is to test hypotheses based on neuropsychological and behavioral measures, i.e., whether certain factors (e.g., related to life events) are associated with an outcome (e.g., depression). In…

Machine Learning · Computer Science 2022-08-01 Magdalini Paschali , Qingyu Zhao , Ehsan Adeli , Kilian M. Pohl

We consider estimation in a particular semiparametric regression model for the mean of a counting process with ``panel count'' data. The basic model assumption is that the conditional mean function of the counting process is of the form…

Statistics Theory · Mathematics 2009-09-29 Jon A. Wellner , Ying Zhang

The Latent Block Model (LBM) is a model-based method to cluster simultaneously the $d$ columns and $n$ rows of a data matrix. Parameter estimation in LBM is a difficult and multifaceted problem. Although various estimation strategies have…

Statistics Theory · Mathematics 2020-02-26 Vincent Brault , Christine Keribin , Mahendra Mariadassou

Early prognosis of Alzheimer's dementia is hard. Mild cognitive impairment (MCI) typically precedes Alzheimer's dementia, yet only a fraction of MCI individuals will progress to dementia, even when screened using biomarkers. We propose here…

Quantitative Methods · Quantitative Biology 2018-03-05 Christian Dansereau , Angela Tam , AmanPreet Badhwar , Sebastian Urchs , Pierre Orban , Pedro Rosa-Neto , Pierre Bellec

The beta process has recently been widely used as a nonparametric prior for different models in machine learning, including latent feature models. In this paper, we prove the asymptotic consistency of the finite dimensional approximation of…

Statistics Theory · Mathematics 2014-11-14 Luai Al Labadi , Mahmoud Zarepour

I study peer effects that arise from irreversible decisions in the absence of a standard social equilibrium. I model a latent sequence of decisions in continuous time and obtain a closed-form expression for the likelihood, which allows to…

Econometrics · Economics 2026-02-18 Vincent Starck

Introduction: Alzheimer's disease is a type of dementia in which early diagnosis plays a major rule in the quality of treatment. Among new works in the diagnosis of Alzheimer's disease, there are many of them analyzing the voice stream…

Machine Learning · Computer Science 2019-10-02 S. Soroush Haj Zargarbashi , Bagher Babaali

Latent fingerprint matching is a daunting task, primarily due to the poor quality of latent fingerprints. In this study, we propose a deep-learning based dense minutia descriptor (DMD) for latent fingerprint matching. A DMD is obtained by…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Zhiyu Pan , Yongjie Duan , Xiongjun Guan , Jianjiang Feng , Jie Zhou

Continuous-time multistate models are widely used for analyzing interval-censored data on disease progression over time. Sometimes, diseases manifest differently and what appears to be a coherent collection of symptoms is the expression of…

Methodology · Statistics 2024-10-08 Yidan Shi , Leilei Zeng , Mary E. Thompson , Suzanne L. Tyas

Dementia is a syndrome characterised by the decline of different cognitive abilities. Alzheimer's Disease (AD) is the most common dementia affecting cognitive domains such as memory and learning, perceptual-motion or executive function.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 Juan Manuel Fernández Montenegro

Serious games have proven to be effective tools for screening cognitive impairments and supporting diagnosis in patients with neurodegenerative diseases like Alzheimer's and Parkinson's. They also offer cognitive training benefits.…

Formal Languages and Automata Theory · Computer Science 2026-02-04 Elisabetta De Maria , Christopher Leturc

Latent feature modeling allows capturing the latent structure responsible for generating the observed properties of a set of objects. It is often used to make predictions either for new values of interest or missing information in the…

Machine Learning · Statistics 2018-03-09 Isabel Valera , Melanie F. Pradier , Maria Lomeli , Zoubin Ghahramani

Dementia is characterized by a decline in memory and thinking that is significant enough to impair function in activities of daily living. Patients seen in dementia specialty clinics are highly heterogeneous with a variety of different…

Machine Learning · Computer Science 2026-02-06 Sayantan Kumar , Zachary Abrams , Suzanne Schindler , Nupur Ghoshal , Philip Payne

Timely and accurate diagnosis of neurodegenerative disorders, such as Alzheimer's disease, is central to disease management. Existing deep learning models require large-scale annotated datasets and often function as "black boxes".…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Duy-Cat Can , Quang-Huy Tang , Huong Ha , Binh T. Nguyen , Oliver Y. Chén

Mathematical models of cognition are often memoryless and ignore potential fluctuations of their parameters. However, human cognition is inherently dynamic. Thus, we propose to augment mechanistic cognitive models with a temporal dimension…

Human-like personality traits have recently been discovered in large language models, raising the hypothesis that their (known and as yet undiscovered) biases conform with human latent psychological constructs. While large conversational…

Computation and Language · Computer Science 2025-01-14 Maor Reuben , Ortal Slobodin , Aviad Elyshar , Idan-Chaim Cohen , Orna Braun-Lewensohn , Odeya Cohen , Rami Puzis

Modeling physiological time-series in ICU is of high clinical importance. However, data collected within ICU are irregular in time and often contain missing measurements. Since absence of a measure would signify its lack of importance, the…

Machine Learning · Computer Science 2017-07-18 Phuoc Nguyen , Truyen Tran , Svetha Venkatesh

High-dimensional neuroimaging data presents challenges for assessing neurodegenerative diseases due to complex non-linear relationships. Variational Autoencoders (VAEs) can encode scans into lower-dimensional latent spaces capturing…

In this study, we develop a latent factor model for analysing high-dimensional binary data. Specifically, a standard probit model is used to describe the regression relationship between the observed binary data and the continuous latent…

Methodology · Statistics 2024-04-15 Jiaxin Shi , Yuan Gao , Rui Pan , Hansheng Wang

Process modeling and understanding are fundamental for advanced human-computer interfaces and automation systems. Most recent research has focused on activity recognition, but little has been done on sensor-based detection of process…