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We present a theoretical study aiming at model fitting for sensory neurons. Conventional neural network training approaches are not applicable to this problem due to lack of continuous data. Although the stimulus can be considered as a…

Neurons and Cognition · Quantitative Biology 2017-09-28 R. Ozgur Doruk , Kechen Zhang

Neuroscientists have worked on the problem of estimating synaptic properties, such as connectivity and strength, from simultaneously recorded spike trains since the 1960s. Recent years have seen renewed interest in the problem, coinciding…

Neurons and Cognition · Quantitative Biology 2024-05-07 Zach Saccomano , Sam Mckenzie , Horacio Rotstein , Asohan Amarasingham

The relative timing of action potentials in neurons recorded from local cortical networks often shows a non-trivial dependence, which is then quantified by cross-correlation functions. Theoretical models emphasize that such spike train…

Neurons and Cognition · Quantitative Biology 2017-06-28 Taskin Deniz , Stefan Rotter

The action potential constitutes the digital component of the signaling dynamics of neurons. But the biophysical nature of the full-time course of the action potential associated with changes in membrane potential is mathematically distinct…

Neurons and Cognition · Quantitative Biology 2026-04-16 Gabriel A. Silva

Modern well-performing approaches to neural decoding are based on machine learning models such as decision tree ensembles and deep neural networks. The wide range of algorithms that can be utilized to learn from neural spike trains, which…

Neurons and Cognition · Quantitative Biology 2023-01-30 Ivan Lazarevich , Ilya Prokin , Boris Gutkin , Victor Kazantsev

Recently, the SPIKE-distance has been proposed as a parameter-free and time-scale independent measure of spike train synchrony. This measure is time-resolved since it relies on instantaneous estimates of spike train dissimilarity. However,…

Data Analysis, Statistics and Probability · Physics 2012-12-11 Thomas Kreuz , Daniel Chicharro , Conor Houghton , Ralph G Andrzejak , Florian Mormann

Accurate statistical models of neural spike responses can characterize the information carried by neural populations. But the limited samples of spike counts during recording usually result in model overfitting. Besides, current models…

Quantitative Methods · Quantitative Biology 2021-06-17 Qi She , Xiaoli Wu , Beth Jelfs , Adam S. Charles , Rosa H. M. Chan

Neurons in the central nervous system communicate with each other with the help of series of Action Potentials, or spike trains. Various studies have shown that neurons encode information in different features of spike trains, such as the…

Neurons and Cognition · Quantitative Biology 2014-10-21 Shubhanshu Shekhar , Kaushik Majumdar

We consider the evolution of a network of neurons, focusing on the asymptotic behavior of spikes dynamics instead of membrane potential dynamics. The spike response is not sought as a deterministic response in this context, but as a…

Data Analysis, Statistics and Probability · Physics 2010-08-27 J. C. Vasquez , B. Cessac , T. Viéville

A scheme is derived for learning connectivity in spiking neural networks. The scheme learns instantaneous firing rates that are conditional on the activity in other parts of the network. The scheme is independent of the choice of neuron…

Neural and Evolutionary Computing · Computer Science 2015-02-23 James A. Henderson , TingTing A. Gibson , Janet Wiles

Recurrent neural networks are powerful tools for understanding and modeling computation and representation by populations of neurons. Continuous-variable or "rate" model networks have been analyzed and applied extensively for these…

Neurons and Cognition · Quantitative Biology 2016-01-29 Brian DePasquale , Mark M. Churchland , L. F. Abbott

Sampling considerations limit the experimental conditions under which information theoretic analyses of neurophysiological data yield reliable results. We develop a procedure for computing the full temporal entropy and information of…

Biological Physics · Physics 2009-11-06 Simon R. Schultz , Stefano Panzeri

Spike-sorting techniques attempt to classify a series of noisy electrical waveforms according to the identity of the neurons that generated them. Existing techniques perform this classification ignoring several properties of actual neurons…

Quantitative Methods · Quantitative Biology 2007-05-23 Christophe Pouzat

Spiking neural network is a type of artificial neural network in which neurons communicate between each other with spikes. Spikes are identical Boolean events characterized by the time of their arrival. A spiking neuron has internal…

Neural and Evolutionary Computing · Computer Science 2016-02-16 Oleg Y. Sinyavskiy

We address the problem of identifying functional interactions among stochastic neurons with variable-length memory from their spiking activity. The neuronal network is modeled by a stochastic system of interacting point processes with…

Applications · Statistics 2025-07-01 Ricardo F. Ferreira , Matheus E. Pacola , Vitor G. Schiavone , Rodrigo F. O. Pena

Humans perform remarkably well in many cognitive tasks including pattern recognition. However, the neuronal mechanisms underlying this process are not well understood. Nevertheless, artificial neural networks, inspired in brain circuits,…

Neurons and Cognition · Quantitative Biology 2018-06-28 Gianluca Susi , Luis Anton Toro , Leonides Canuet , Maria Eugenia Lopez , Fernando Maestu , Claudio R. Mirasso , Ernesto Pereda

Now that spike trains from many neurons can be recorded simultaneously, there is a need for methods to decode these data to learn about the networks that these neurons are part of. One approach to this problem is to adjust the parameters of…

Quantitative Methods · Quantitative Biology 2011-06-10 John Hertz , Yasser Roudi , Joanna Tyrcha

At the single-neuron level, precisely timed spikes can either constitute firing-rate codes or spike-pattern codes that utilize the relative timing between consecutive spikes. There has been little experimental support for the hypothesis…

Neurons and Cognition · Quantitative Biology 2009-12-18 Hugo Gabriel Eyherabide , Ariel Rokem , Andreas V. M. Herz , Ines Samengo

Sparse sequences of neural spikes are posited to underlie aspects of working memory, motor production, and learning. Discovering these sequences in an unsupervised manner is a longstanding problem in statistical neuroscience. Promising…

Machine Learning · Statistics 2020-10-13 Alex H. Williams , Anthony Degleris , Yixin Wang , Scott W. Linderman

Using precise times of every spike, spiking supervised learning has more effects on complex spatial-temporal pattern than supervised learning only through neuronal firing rates. The purpose of spiking supervised learning after…

Neural and Evolutionary Computing · Computer Science 2019-02-12 Guojun Chen , Xianghong Lin , Guoen Wang