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This article deals with the sequential design of experiments for (deterministic or stochastic) multi-fidelity numerical simulators, that is, simulators that offer control over the accuracy of simulation of the physical phenomenon or system…

Traditional accelerated life test plans are typically based on optimizing the C-optimality for minimizing the variance of an interested quantile of the lifetime distribution. The traditional methods rely on some specified planning values…

Applications · Statistics 2018-12-04 Lu Lu , I-Chen Lee , Yili Hong

We have developed a model for experiments in which the bias current applied to a Josephson junction is slowly increased from zero until the junction switches from its superconducting zero-voltage state, and the bias value at which this…

Statistical Mechanics · Physics 2012-03-06 James A. Blackburn , Matteo Cirillo , Niels Grønbech-Jensen

We review recent theoretical and experimental progress in quantum state engineering with Josephson junction devices. The concepts of quantum computing have stimulated an increased activity in the field. Either charges or phases (fluxes) of…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Yuriy Makhlin , Gerd Schoen , Alexander Shnirman

Group sequential designs drive innovation in clinical, industrial, and corporate settings. Early stopping for failure in sequential designs conserves experimental resources, whereas early stopping for success accelerates access to improved…

Methodology · Statistics 2025-11-27 Luke Hagar , Shirin Golchi , Marina B. Klein

We have studied the switching behaviour of a small capacitance Josephson junction both in experiment, and by numerical simulation of a model circuit. The switching is a comples process involving the transition between two dynamical states…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Joachim Sjostrand , Jochen Walter , David Haviland , Hans Hansson , Anders Karlhede

Switchback experiments, where a firm sequentially exposes an experimental unit to random treatments, are among the most prevalent designs used in the technology sector, with applications ranging from ride-hailing platforms to online…

Methodology · Statistics 2025-09-18 Iavor Bojinov , David Simchi-Levi , Jinglong Zhao

We investigate the merits of replication, and provide methods for optimal design (including replicates), with the goal of obtaining globally accurate emulation of noisy computer simulation experiments. We first show that replication can be…

Methodology · Statistics 2019-01-28 Mickael Binois , Jiangeng Huang , Robert B Gramacy , Mike Ludkovski

This paper considers sequential adaptive estimation of sparse signals under a constraint on the total sensing effort. The advantage of adaptivity in this context is the ability to focus more resources on regions of space where signal…

Methodology · Statistics 2013-04-03 Dennis Wei , Alfred O. Hero

In this work we present strategies for (optimal) measurement selection in model-based sequential diagnosis. In particular, assuming a set of leading diagnoses being given, we show how queries (sets of measurements) can be computed and…

Artificial Intelligence · Computer Science 2017-05-30 Patrick Rodler , Wolfgang Schmid , Konstantin Schekotihin

Simulation models of critical systems often have parameters that need to be calibrated using observed data. For expensive simulation models, calibration is done using an emulator of the simulation model built on simulation output at…

Methodology · Statistics 2023-08-24 Özge Sürer , Matthew Plumlee , Stefan M. Wild

We tackle the problem of accurate simulations of switching currents arising from tunnel events in the washboard potentials associated to Josephson junctions. The measurements of the probability distribution of the switching currents is…

Quantum Physics · Physics 2017-07-05 Vincenzo Pierro , Giovanni Filatrella

Experimental design has emerged as a powerful approach for improving the sample efficiency of A/B testing, yet existing designs rely critically on correctly specified models. We study robust sequential experimental design under model…

Machine Learning · Statistics 2026-05-14 Qianglin Wen , Xiangkun Wu , Chengchun Shi , Ting Li , Niansheng Tang , Yingying Zhang , Hongtu Zhu

Selecting input variables or design points for statistical models has been of great interest in adaptive design and active learning. Motivated by two scientific examples, this paper presents a strategy of selecting the design points for a…

Machine Learning · Statistics 2021-02-12 Chiwoo Park , Peihua Qiu , Jennifer Carpena-Núñez , Rahul Rao , Michael Susner , Benji Maruyama

Low-capacitance Josephson junctions, where Cooper pairs tunnel coherently while Coulomb blockade effects allow the control of the total charge, provide physical realizations of quantum bits (qubits), with logical states differing by one…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Yuriy Makhlin , Gerd Schoen , Alexander Shnirman

The ultimate spatial limit to establish a Josephson coupling between two superconducting electrodes is an atomic-scale junction. The Josephson effect in such ultrasmall junctions has been used to unveil new switching dynamics, study…

We examine in theory and by numerical simulation, the dynamic process of switching from a zero voltage to a finite voltage state in a Josephson junction circuit. The theoretical model describes small capacitance Josephson junctions which…

Superconductivity · Physics 2009-11-11 J. Sjostrand , J. Walter , E. Tholen , H. Hansson , D. Haviland , A. Karlhede

Optimal design is a critical yet challenging task within many applications. This challenge arises from the need for extensive trial and error, often done through simulations or running field experiments. Fortunately, sequential optimal…

Machine Learning · Computer Science 2025-03-25 Xubo Yue , Raed Al Kontar , Albert S. Berahas , Yang Liu , Blake N. Johnson

Using Bayesian experimental design techniques, we have shown that for a single two-level quantum mechanical system under strong (projective) measurement, the dynamical parameters of a model Hamiltonian can be estimated with exponentially…

Quantum Physics · Physics 2012-06-05 Christopher Ferrie , Christopher E. Granade , D. G. Cory

Deciding which idea is worth prototyping is a central concern in iterative design. A prototype should be produced when the expected improvement is high and the cost is low. However, this is hard to decide, because costs can vary…

Human-Computer Interaction · Computer Science 2026-02-03 Thomas Langerak , Renate Zhang , Ziyuan Wang , Per Ola Kristensson , Antti Oulasvirta