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We study a general setting of neutral evolution in which the population is of finite, constant size and can have spatial structure. Mutation leads to different genetic types ("traits"), which can be discrete or continuous. Under minimal…

Populations and Evolution · Quantitative Biology 2018-11-02 Alex McAvoy , Ben Adlam , Benjamin Allen , Martin A. Nowak

Fluctuations in the measured mRNA levels of unperturbed cells under fixed conditions have often been viewed as an impediment to the extraction of information from expression profiles. Here, we argue that such expression fluctuations should…

Molecular Networks · Quantitative Biology 2007-05-23 William W. Chen , Jeremy L. England , Eugene I. Shakhnovich

The functioning of animal as well as human societies fundamentally relies on cooperation. Yet, defection is often favorable for the selfish individual, and social dilemmas arise. Selection by individuals' fitness, usually the basic driving…

Populations and Evolution · Quantitative Biology 2009-09-26 Jonas Cremer , Tobias Reichenbach , Erwin Frey

We review generalized Fluctuation-Dissipation Relations which are valid under general conditions even in ``non-standard systems'', e.g. out of equilibrium and/or without a Hamiltonian structure. The response functions can be expressed in…

Statistical Mechanics · Physics 2019-09-10 A. Sarracino , A. Vulpiani

A growing number of biological, soft, and active matter systems are observed to exhibit normal diffusive dynamics with a linear growth of the mean squared displacement, yet with a non-Gaussian distribution of increments. Based on the…

Statistical Mechanics · Physics 2017-04-12 A. V. Chechkin , F. Seno , R. Metzler , I. M. Sokolov

We analyze a reaction-diffusion system describing the growth of microbial species in a model of flocculation type that arises in biology. Existence of global classical positive solutions is proved under general growth assumptions, with…

Analysis of PDEs · Mathematics 2023-01-19 Jeffrey Morgan , Samia Zermani

Deterministically growing (wild-type) populations which seed stochastically developing mutant clones have found an expanding number of applications from microbial populations to cancer. The special case of exponential wild-type population…

Populations and Evolution · Quantitative Biology 2016-10-27 Michael D. Nicholson , Tibor Antal

The gut microbiota features important genetic diversity, and the specific spatial features of the gut may shape evolution within this environment. We investigate the fixation probability of neutral bacterial mutants within a minimal model…

Biological Physics · Physics 2022-01-03 Darka Labavić , Claude Loverdo , Anne-Florence Bitbol

We study the population profile in a simple discrete time model of population dynamics. Our model, which is closely related to certain ``bit-string'' models of evolution, incorporates competition for resources via a population dependent…

Statistical Mechanics · Physics 2009-10-31 Martin Howard , R. K. P. Zia

Bursting and non-renewal processes are common phenomena in birth-death process, yet no theory can quantitatively describe a non-renewal birth process with bursting. Here, we present a theoretical model that yields the product number…

Molecular Networks · Quantitative Biology 2019-08-28 Seong Jun Park , Jaeyoung Sung

We consider a model of N two-colors urns in which the reinforcement of each urn depends also on the content of all the other urns. This interaction is of mean-field type and it is tuned by a parameter $\alpha$ in [0,1]; in particular, for…

Probability · Mathematics 2015-03-20 Irene Crimaldi , Paolo Dai Pra , Ida Germana Minelli

We study fixation probabilities and times as a consequence of neutral genetic drift in subdivided populations, motivated by a model of the cultural evolutionary process of language change that is described by the same mathematics as the…

Populations and Evolution · Quantitative Biology 2015-05-26 R A Blythe

We consider the dynamics of the disordered trap model, which is known to be completely out-of-equilibrium and to present strong localization effects in its aging phase. We are interested into the influence of an external force, when it is…

Condensed Matter · Physics 2009-11-10 Cecile Monthus

We model the growth of a cell population using a piecewise deterministic Markov branching tree. In this model, each cell splits into two offspring at a division rate $B(x)$, which depends on its size $x$. The size of each cell increases…

Probability · Mathematics 2024-09-06 Nathalie Krell

In their work [Proc. Natl. Acad. Sci. USA 112 (2015) E5725], Bosse et al. experimentally showed that virus capsid exhibits not only normal diffusion but also anomalous diffusion in nucleus of a living cell. There, it was found that the…

Biological Physics · Physics 2018-04-06 Yuichi Itto

The "Brownian bees" model describes a system of $N$ independent branching Brownian particles. At each branching event the particle farthest from the origin is removed, so that the number of particles remains constant at all times.…

Statistical Mechanics · Physics 2021-03-30 Baruch Meerson , Pavel Sasorov

We propose a class of evolutionary models that involves an arbitrary exchangeable process as the breeding process and different selection schemes. In those models, a new genome is born according to the breeding process, and then a genome is…

Neural and Evolutionary Computing · Computer Science 2020-08-25 Jüri Lember , Chris Watkins

In the growth of bacterial colonies, a great variety of complex patterns are observed in experiments, depending on external conditions and the bacterial species. Typically, existing models employ systems of reaction-diffusion equations or…

Biological Physics · Physics 2019-11-12 Lautaro Vassallo , David Hansmann , Lidia A. Braunstein

We study fluctuations in the number of zeros of random analytic functions given by a Taylor series whose coefficients are independent complex Gaussians. When the functions are entire, we find sharp bounds for the asymptotic growth rate of…

Probability · Mathematics 2021-09-17 Avner Kiro , Alon Nishry

We investigate propagation of perturbations of equilibrium states for a wide class of 1D interacting particle systems. The class of systems considered incorporates zero range, $K$-exclusion, mysanthropic, `bricklayers' models, and much…

Probability · Mathematics 2007-05-23 Balint Toth , Benedek Valko