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A saturated D-optimal design is a {+1,-1} square matrix of given order with maximal determinant. We search for saturated D-optimal designs of orders 19 and 37, and find that known matrices due to Smith, Cohn, Orrick and Solomon are optimal.…

Combinatorics · Mathematics 2015-03-13 Richard P. Brent , William Orrick , Judy-anne Osborn , Paul Zimmermann

Standard optimality criteria (e.g. A-, D-optimality criterion, etc.) have been commonly used for obtaining optimal designs. For a given statistical model, standard criteria assume the error variance is known at the design stage. However, in…

Methodology · Statistics 2017-01-27 Md. Shaddam Hossain Bagmar , Wasimul Bari , A. H. M. Mahbub Latif

Designs which are minimax in the presence of model misspecifications have been constructed so as to minimize the maximum, over classes of alternate response models, of the integrated mean squared error of the predicted values. This mean…

Statistics Theory · Mathematics 2026-03-05 Douglas P. Wiens

In the assessment and selection of supersaturated designs, the aliasing structure of interaction effects is usually ignored by traditional criteria such as $E(s^2)$-optimality. We introduce the Summary of Effect Aliasing Structure (SEAS)…

Methodology · Statistics 2021-01-18 Frederick Kin Hing Phoa , Yi-Hua Liao , David C. Woods , Shah-Kae Chou

This paper considers the construction of minimum aberration (MA) blocked factorial designs. Based on coding theory, the concept of minimum moment aberration due to Xu [Statist. Sinica 13 (2003) 691--708] for unblocked designs is extended to…

Statistics Theory · Mathematics 2007-06-13 Hongquan Xu

Chen and Cheng [Ann. Statist. 34 (2006) 546--558] discussed the method of doubling for constructing two-level fractional factorial designs. They showed that for $9N/32\le n\le 5N/16$, all minimum aberration designs with $N$ runs and $n$…

Statistics Theory · Mathematics 2008-12-18 Hongquan Xu , Ching-Shui Cheng

Saturating sets are combinatorial objects in projective spaces over finite fields that have been intensively investigated in the last three decades. They are related to the so-called covering problem of codes in the Hamming metric. In this…

Combinatorics · Mathematics 2023-09-22 Daniele Bartoli , Martino Borello , Giuseppe Marino

Bayesian optimality criteria provide a robust design strategy to parameter misspecification. We develop an approximate design theory for Bayesian $D$-optimality for non-linear regression models with covariates subject to measurement errors.…

Methodology · Statistics 2016-05-16 Maria Konstantinou , Holger Dette

In areas such as kernel smoothing and non-parametric regression there is emphasis on smooth interpolation and smooth statistical models. Splines are known to have optimal smoothness properties in one and higher dimensions. It is shown, with…

Computation · Statistics 2008-09-29 Ron A. Bates , Hugo Maruri-Aguilar , Henry P. Wynn

Inspired by the "generalized t-designs" defined by Cameron [P. J. Cameron, A generalisation of t-designs, Discrete Math. 309 (2009), 4835--4842], we define a new class of combinatorial designs which simultaneously provide a generalization…

Combinatorics · Mathematics 2015-03-17 Robert F. Bailey , Andrea C. Burgess , Michael S. Cavers , Karen Meagher

Tang and Xu [Biometrika 101 (2014) 333-350] applied the minimum $\beta$-aberration criterion to selecting optimal designs for screening quantitative factors. They provided a statistical justification showing that minimum $\beta$-aberration…

Statistics Theory · Mathematics 2014-09-04 Po Yang , Chang-Yun Lin

Augmented designs are typically used in early-stage breeding programs to compare single replicates of test entries by combining them with replicated check varieties. One or two dimensional incomplete blocking can be incorporated in the…

Methodology · Statistics 2025-11-24 E. R. Williams , H-P. Piepho

We investigate block designs, under the A- and MV-criteria, when each treatment can have only one or two replications due to resource constraints, as can happen, for example, in early generation varietal trials. While these are commonly…

Statistics Theory · Mathematics 2026-03-25 R. A. Bailey , Rahul Mukerjee

Nonregular fractional factorial designs such as Plackett-Burman designs and other orthogonal arrays are widely used in various screening experiments for their run size economy and flexibility. The traditional analysis focuses on main…

Methodology · Statistics 2008-12-17 Hongquan Xu , Frederick K. H. Phoa , Weng Kee Wong

We consider design issues for toxicology studies when we have a continuous response and the true mean response is only known to be a member of a class of nested models. This class of non-linear models was proposed by toxicologists who were…

Statistics Theory · Mathematics 2010-11-29 Holger Dette , Andrey Pepelyshev , Piter Shpilev , Weng Kee Wong

Among the major difficulties that one may encounter when estimating parameters in a nonlinear regression model are the nonuniqueness of the estimator, its instability with respect to small perturbations of the observations and the presence…

Statistics Theory · Mathematics 2014-08-29 Andrej Pázman , Luc Pronzato

We typically construct optimal designs based on a single objective function. To better capture the breadth of an experiment's goals, we could instead construct a multiple objective optimal design based on multiple objective functions. While…

Methodology · Statistics 2023-03-09 Lucy L. Gao , Jane J. Ye , Shangzhi Zeng , Julie Zhou

We contemplate an experimental situation in a $2^k$-factorial experiment with acute resource crunch so that we need to conduct just a saturated design [SD] - with the understanding that precision of the estimates cannot be estimated from…

Statistics Theory · Mathematics 2019-11-01 Francois Domagni , Samad Hedayat , Sinha Bikas

Let $\Pi_q$ be an arbitrary finite projective plane of order $q$. A subset $S$ of its points is called saturating if any point outside $S$ is collinear with a pair of points from $S$. Applying probabilistic tools we improve the upper bound…

Combinatorics · Mathematics 2017-11-28 Zoltán Lóránt Nagy

Consider the problem of constructing an experimental design, optimal for estimating parameters of a given statistical model with respect to a chosen criterion. To address this problem, the literature usually provides a single solution.…

Computation · Statistics 2024-11-05 Radoslav Harman , Lenka Filová , Samuel Rosa