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Molecular phenotypes link genomic information with organismic functions, fitness, and evolution. Quantitative traits are complex phenotypes that depend on multiple genomic loci. In this paper, we study the adaptive evolution of a…

Populations and Evolution · Quantitative Biology 2015-06-19 Torsten Held , Armita Nourmohammad , Michael Lässig

A major aim of evolutionary biology is to explain the respective roles of adaptive versus non-adaptive changes in the evolution of complexity. While selection is certainly responsible for the spread and maintenance of complex phenotypes,…

Populations and Evolution · Quantitative Biology 2017-01-17 Thomas LaBar , Christoph Adami

We consider a stochastic individual based model where each predator searches during a random time and then manipulates its prey or rests. The time distributions may be non-exponential. An age structure allows to describe these interactions…

Dynamical Systems · Mathematics 2021-03-31 Vincent Bansaye , Bertand Cloez

We consider a metapopulation made up of $K$ demes, each containing $N$ individuals bearing a heritable quantitative trait. Demes are connected by migration and undergo independent Moran processes with mutation and selection based on trait…

Probability · Mathematics 2025-03-18 Amaury Lambert , Hélène Leman , Hélène Morlon , Josué Tchouanti

In this paper we study the long term evolution of a continuous time Markov chain formed by two interacting birth-and-death processes. The interaction between the processes is modelled by transition rates which are functions with suitable…

Probability · Mathematics 2017-03-23 Mikhail Menshikov , Vadim Shcherbakov

The importance of mutator clones in the adaptive evolution of asexual populations is not fully understood. Here we address this problem by using an ab initio microscopic model of living cells, whose fitness is derived directly from their…

Biomolecules · Quantitative Biology 2009-02-17 Muyoung Heo , Louis Kang , Eugene Shakhnovich

We investigate a simple quantitative genetics model subjet to a gradual environmental change from the viewpoint of the phylogenies of the living individuals. We aim to understand better how the past traits of their ancestors are shaped by…

Probability · Mathematics 2021-04-22 Vincent Calvez , Benoît Henry , Sylvie Méléard , Viet Chi Tran

Density dependent Markov population processes in large populations of size $N$ were shown by Kurtz (1970, 1971) to be well approximated over finite time intervals by the solution of the differential equations that describe their average…

Probability · Mathematics 2014-10-15 A. D. Barbour , Kais Hamza , Haya Kaspi , Fima Klebaner

We model evolution according to an asymmetric game as occurring in multiple finite populations, one for each role in the game, and study the effect of subjecting individuals to stochastic strategy mutations. We show that, when these…

Populations and Evolution · Quantitative Biology 2015-12-22 Carl Veller , Laura K. Hayward

We study the evolution of large but finite asexual populations evolving in fitness landscapes in which all mutations are either neutral or strongly deleterious. We demonstrate that despite the absence of higher fitness genotypes, adaptation…

Biological Physics · Physics 2007-05-23 Claus O. Wilke

There exists a wide variety of works on the dynamics of large populations ranging from simple heuristic modeling to those based on advanced computer supported methods. Their interconnections, however, remain mostly vague, which…

Dynamical Systems · Mathematics 2023-04-27 Yuri Kozitsky , Krzysztof Pilorz

The coupling between evolutionary and ecological changes (eco-evolutionary dynamics) has been shown to be relevant among diverse species, and is also of interest outside of ecology, i.e. in cancer evolution. These dynamics play an important…

Analysis of PDEs · Mathematics 2026-01-21 Manh Hong Duong , Fabian Spill , Blaine van Rensburg

The Tangled Nature Model of biological and cultural evolution features interacting agents which compete for limited resources and reproduce in an error prone fashion and at a rate depending on the `tangle' of interactions they maintain with…

Populations and Evolution · Quantitative Biology 2016-05-25 Christian Walther Andersen , Paolo Sibani

Migration between different habitats is ubiquitous among biological populations. In this Letter, we study a simple quasispecies model for evolution in two different habitats, with different fitness landscapes, coupled through one-way…

Populations and Evolution · Quantitative Biology 2010-12-23 Bartlomiej Waclaw , Rosalind J. Allen , Martin R. Evans

Infinitely many distinct trait values may arise in populations bearing quantitative traits, and modeling their population dynamics is thus a formidable task. While classical models assume fixed or infinite population size, models in which…

Populations and Evolution · Quantitative Biology 2025-05-08 Ananda Shikhara Bhat

We propose a stochastic model for evolution. Births and deaths of species occur with constant probabilities. Each new species is associated with a fitness sampled from the uniform distribution on [0,1]. Every time there is a death event…

Probability · Mathematics 2010-11-09 Herve Guiol , Fabio P. Machado , Rinaldo B. Schinazi

We consider an approximating sequence of interacting population models with branching, mutation and competition. Each individual is characterized by its trait and the traits of its ancestors. Birth- and death-events happen at exponential…

Probability · Mathematics 2014-12-08 Sandra Kliem

We study the adaptation dynamics of an initially maladapted asexual population with genotypes represented by binary sequences of length $L$. The population evolves in a maximally rugged fitness landscape with a large number of local optima.…

Populations and Evolution · Quantitative Biology 2007-05-23 Kavita Jain , Joachim Krug

Existing theoretical models of evolution focus on the relative fitness advantages of different mutants in a population while the dynamic behavior of the population size is mostly left unconsidered. We here present a generic stochastic model…

Populations and Evolution · Quantitative Biology 2010-10-20 Anna Melbinger , Jonas Cremer , Erwin Frey

This paper studies birth and death processes in interactive random environments where the birth and death rates and the dynamics of the state of the environment are dependent on each other. Two models of a random environment are considered:…

Probability · Mathematics 2022-06-28 Guodong Pang , Andrey Sarantsev , Yuri Suhov