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Integrase proteins acting on circular double-stranded DNA often change its topology by transforming unknotted circles into torus knots and links. Two systems of tangle equations--corresponding to the two initial DNA sequences--arise when…

Geometric Topology · Mathematics 2007-05-23 Dorothy Buck , Cynthia Verjovsky Marcotte

We develop topological methods for analyzing difference topology experiments involving 3-string tangles. Difference topology is a novel technique used to unveil the structure of stable protein-DNA complexes involving two or more DNA…

Geometric Topology · Mathematics 2016-01-20 Isabel K. Darcy , John Luecke , Mariel Vazquez

This paper presents a novel DNA sequences alignment method based on inverted index. Now most large scale information retrieval system are all use inverted index as the basic data structure. But its application in DNA sequence alignment is…

Genomics · Quantitative Biology 2013-07-02 Wang Liang , Zhao KaiYong

Some natural proteins display recurrent structural patterns. Despite being highly similar at the tertiary structure level, repetitions within a single repeat protein can be extremely variable at the sequence level. We propose a mathematical…

Biomolecules · Quantitative Biology 2015-10-12 Pablo Turjanski , R. Gonzalo Parra , Rocío Espada , Verónica Becher , Diego U. Ferreiro

Problems of search and recognition appear over different scales in biological systems. In this review we focus on the challenges posed by interactions between proteins, in particular transcription factors, and DNA and possible mechanisms…

Biomolecules · Quantitative Biology 2015-03-19 M. Sheinman , O. Bénichou , Y. Kafri , R. Voituriez

Recent studies have revealed that for the majority of species the length distributions of duplicated sequences in natural DNA follow a power-law tail. We study duplication-mutation models for processes in natural DNA sequences and the…

Quantitative Methods · Quantitative Biology 2015-06-04 M. V. Koroteev

To increase the information capacity of DNA storage, composite DNA letters were introduced. We propose a novel channel model for composite DNA in which composite sequences are decomposed into ordered standard non-composite sequences. The…

Information Theory · Computer Science 2025-10-31 Besart Dollma , Ohad Elishco , Eitan Yaakobi

We study systems of $2$-tangle equations which play an important role in the analysis of enzyme actions on DNA strands. We show that every system of framed tangle equations has at most one framed rational solution. Furthermore, we show that…

Geometric Topology · Mathematics 2024-05-08 Adam S. Sikora

A splicing system is a formal model of a recombinant behaviour of sets of double stranded DNA molecules when acted on by restriction enzymes and ligase. In this survey we will concentrate on a specific behaviour of a type of splicing…

Formal Languages and Automata Theory · Computer Science 2015-10-07 Luc Boasson , Paola Bonizzoni , Clelia De Felice , Isabelle Fagnot , Gabriele Fici , Rocco Zaccagnino , Rosalba Zizza

The deterministic selection-recombination equation describes the evolution of the genetic type composition of a population under selection and recombination in a law of large numbers regime. So far, an explicit solution has seemed out of…

Probability · Mathematics 2023-04-26 Ellen Baake , Frederic Alberti

We present a new one parameter family of second derivative discontinuous solutions to the simplest scale invariant linear ordinary differential equation. We also point out how the construction could be extended to generate families of…

General Mathematics · Mathematics 2010-01-12 Dhurjati Prasad Datta , Manoj Kumar Bose

In this study, a recursive solution technique in conjunction with generalized integrating factors is presented and applied to address first and second order linear differential equations. This approach demonstrates practical utility in…

Mathematical Physics · Physics 2025-03-03 Everardo Rivera-Oliva

In this paper we investigate a variety of deep learning strategies for solving inverse problems. We classify existing deep learning solutions for inverse problems into three categories of Direct Mapping, Data Consistency Optimizer, and Deep…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 Shima Kamyab , Zohreh Azimifar , Rasool Sabzi , Paul Fieguth

A permutation may be represented by a collection of paths in the plane. We consider a natural class of such representations, which we call tangles, in which the paths consist of straight segments at 45 degree angles, and the permutation is…

Discrete Mathematics · Computer Science 2013-06-19 Sergey Bereg , Alexander E. Holroyd , Lev Nachmanson , Sergey Pupyrev

This article constructs two families of nodal solutions to the Yamabe equation, each concentrating along two planar circles. One family is conformally equivalent to the one previously obtained by Medina--Musso. The second family is a…

Analysis of PDEs · Mathematics 2026-04-06 Yuanli Li , Liming Sun

Our purpose in this paper is to study when a planar differential system polynomial in one variable linearizes in the sense that it has an inverse integrating factor which can be constructed by means of the solutions of linear differential…

Dynamical Systems · Mathematics 2007-10-29 Hector Giacomini , Jaume Gine , Maite Grau

The linear inverse problem is fundamental to the development of various scientific areas. Innumerable attempts have been carried out to solve different variants of the linear inverse problem in different applications. Nowadays, the rapid…

Signal Processing · Electrical Eng. & Systems 2020-10-30 Yanna Bai , Wei Chen , Jie Chen , Weisi Guo

The ability to store data in the DNA of a living organism has applications in a variety of areas including synthetic biology and watermarking of patented genetically-modified organisms. Data stored in this medium is subject to errors…

Information Theory · Computer Science 2016-11-17 Siddharth Jain , Farzad Farnoud , Moshe Schwartz , Jehoshua Bruck

Recent work in machine learning shows that deep neural networks can be used to solve a wide variety of inverse problems arising in computational imaging. We explore the central prevailing themes of this emerging area and present a taxonomy…

Image and Video Processing · Electrical Eng. & Systems 2020-05-14 Gregory Ongie , Ajil Jalal , Christopher A. Metzler , Richard G. Baraniuk , Alexandros G. Dimakis , Rebecca Willett

This paper introduces a new solution to DNA storage that integrates all three steps of retrieval, namely clustering, reconstruction, and error correction. DNA-correcting codes are presented as a unique solution to the problem of ensuring…

Information Theory · Computer Science 2024-07-02 Avital Boruchovsky , Daniella Bar-Lev , Eitan Yaakobi
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