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Mathematical models of biological systems are beginning to be used for safety-critical applications, where large numbers of repeated model evaluations are required to perform uncertainty quantification and sensitivity analysis. Most of…

Computation · Statistics 2018-05-28 Sanmitra Ghosh , David J. Gavaghan , Gary R. Mirams

Bayesian parameter inference is one of the key elements for model selection in cosmological research. However, the available inference tools require a large number of calls to simulation codes which can lead to high and sometimes even…

Cosmology and Nongalactic Astrophysics · Physics 2024-06-10 Sven Günther

A growing cohort of experimental linear photonic networks implementing Gaussian boson sampling (GBS) have now claimed quantum advantage. However, many open questions remain on how to effectively verify these experimental results, as…

Quantum Physics · Physics 2023-08-03 Alexander S. Dellios , Margaret D. Reid , Peter D. Drummond

In environmental studies, realistic simulations are essential for understanding complex systems. Statistical emulation with Gaussian processes (GPs) in functional data models have become a standard tool for this purpose. Traditional…

Applications · Statistics 2024-09-26 R. Jacob Andros , Rajarshi Guhaniyogi , Devin Francom , Donatella Pasqualini

Convolutional Neural Networks (Convnets) have achieved good results in a range of computer vision tasks the recent years. Though given a lot of attention, visualizing the learned representations to interpret Convnets, still remains a…

Computer Vision and Pattern Recognition · Computer Science 2017-02-24 David Malmgren-Hansen , Allan Aasbjerg Nielsen , Rasmus Engholm

In modern science, computer models are often used to understand complex phenomena, and a thriving statistical community has grown around analyzing them. This review aims to bring a spotlight to the growing prevalence of stochastic computer…

Gaussian processes (GPs) serve as flexible surrogates for complex surfaces, but buckle under the cubic cost of matrix decompositions with big training data sizes. Geospatial and machine learning communities suggest pseudo-inputs, or…

Methodology · Statistics 2021-02-05 D. Austin Cole , Ryan Christianson , Robert B. Gramacy

Computer experiments can emulate the physical systems, help computational investigations, and yield analytic solutions. They have been widely employed with many engineering applications (e.g., aerospace, automotive, energy systems.…

Methodology · Statistics 2022-08-23 Yan Wang , Meng Wang , Areej AlBahar , Xiaowei Yue

Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

Intracellular networks process cellular-level information and control cell fate. They can be computationally modeled using Boolean networks, which are implicit-time causal models of discrete binary events. These networks can be embedded in…

Molecular Networks · Quantitative Biology 2025-01-28 John Metzcar , Katie Pletz , Heber L. Rocha , Jordan C Rozum

Optimization of expensive computer models with the help of Gaussian process emulators in now commonplace. However, when several (competing) objectives are considered, choosing an appropriate sampling strategy remains an open question. We…

Optimization and Control · Mathematics 2013-10-03 Victor Picheny

Reciprocal processes are acausal generalizations of Markov processes introduced by Bernstein in 1932. In the literature, a significant amount of attention has been focused on developing dynamical models for reciprocal processes. Recently,…

Machine Learning · Statistics 2018-04-11 Francesca Paola Carli

The use of Gaussian process models is typically limited to datasets with a few tens of thousands of observations due to their complexity and memory footprint. The two most commonly used methods to overcome this limitation are 1) the…

Machine Learning · Statistics 2020-01-16 Vincent Adam , Stefanos Eleftheriadis , Nicolas Durrande , Artem Artemev , James Hensman

The experimental study of neural networks requires simultaneous measurements of a massive number of neurons, while monitoring properties of the connectivity, synaptic strengths and delays. Current technological barriers make such a mission…

Neurons and Cognition · Quantitative Biology 2016-01-12 Amir Goldental , Pinhas Sabo , Shira Sardi , Roni Vardi , Ido Kanter

Questions about information encoded by the brain demand statistical frameworks for inferring relationships between neural firing and features of the world. The landmark discovery of grid cells demonstrates that neurons can represent spatial…

The design space for inertial confinement fusion (ICF) experiments is vast and experiments are extremely expensive. Researchers rely heavily on computer simulations to explore the design space in search of high-performing implosions.…

Machine Learning · Computer Science 2021-05-19 K. D. Humbird , J. L. Peterson , J. Salmonson , B. K. Spears

Gaussian processes (GPs) provide a probabilistic nonparametric representation of functions in regression, classification, and other problems. Unfortunately, exact learning with GPs is intractable for large datasets. A variety of approximate…

Machine Learning · Computer Science 2010-02-23 Yuan Qi , Ahmed H. Abdel-Gawad , Thomas P. Minka

Computational modeling is becoming a widely used methodology in modern neuroscience. However, as the complexity of the phenomena under study increases, the analysis of the results emerging from the simulations concomitantly becomes more…

Neurons and Cognition · Quantitative Biology 2020-03-16 Sergio E. Galindo , Pablo Toharia , Oscar D. Robles , Eduardo Ros , Luis Pastor , Jesús A. Garrido

This paper presents a Bayesian generative model for dependent Cox point processes, alongside an efficient inference scheme which scales as if the point processes were modelled independently. We can handle missing data naturally, infer…

Machine Learning · Statistics 2014-07-28 Tom Gunter , Chris Lloyd , Michael A. Osborne , Stephen J. Roberts

Brain simulation, as one of the latest advances in artificial intelligence, facilitates better understanding about how information is represented and processed in the brain. The extreme complexity of human brain makes brain simulations only…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-17 Xin Du
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