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It has been a puzzling question why some organisms reproduce sexually. Fisher and Muller hypothesized that reproducing by sex can speed up the evolution. They explained that in the sexual reproduction, recombination can combine beneficial…

Probability · Mathematics 2021-04-19 Nantawat Udomchatpitak

Take a continuous-time Galton-Watson tree. If the system survives until a large time $T$, then choose $k$ particles uniformly from those alive. What does the ancestral tree drawn out by these $k$ particles look like? Some special cases are…

Probability · Mathematics 2019-02-14 Simon C. Harris , Samuel G. G. Johnston , Matthew I. Roberts

Recently several authors have proposed stochastic evolutionary models for the growth of complex networks that give rise to power-law distributions. These models are based on the notion of preferential attachment leading to the ``rich get…

Soft Condensed Matter · Physics 2007-05-23 Trevor Fenner , Mark Levene , George Loizou

Natural protein sequences contain a record of their history. A common constraint in a given protein family is the ability to fold to specific structures, and it has been shown possible to infer the main native ensemble by analyzing…

Biomolecules · Quantitative Biology 2017-03-16 Rocío Espada , R. Gonzalo Parra , Thierry Mora , Aleksandra M. Walczak , Diego U. Ferreiro

A decomposable strongly critical Galton-Watson branching process with $N$ types of particles labelled $1,2,...,N$ is considered in which a type~$i$ parent may produce individuals of types $j\geq i$ only. This model may be viewed as a…

Probability · Mathematics 2014-02-28 Vladimir Vatutin

Biological tools such as genetic lineage tracing, three dimensional confocal microscopy and next generation DNA sequencing are providing new ways to quantify the distribution of clones of normal and mutated cells. Population-wide clone size…

Quantitative Methods · Quantitative Biology 2013-11-25 Roshan A , Jones PH , Greenman CD

In this work, we discovered a fundamental connection between selection for protein stability and emergence of preferred structures of proteins. Using standard exact 3-dimensional lattice model we evolve sequences starting from random ones…

Genomics · Quantitative Biology 2007-05-23 Konstantin B. Zeldovich , Igor N. Berezovsky , Eugene I. Sha

We show that textual analysis of microbial genomes reveal telling footprints of the early evolution of the genomes. The frequencies of word occurrence of random DNA sequences considered as texts in their four nucleotides are expected to…

Biological Physics · Physics 2007-05-23 Li-Ching Hsieh , Liaofu Luo , HC Lee

The spread of a particular trait in a cell population often is modelled by an appropriate system of ordinary differential equations describing how the sizes of subpopulations of the cells with the same genome change in time. On the other…

Dynamical Systems · Mathematics 2016-05-26 J. Banasiak , A. Falkiewicz

In large populations, multiple beneficial mutations may be simultaneously spreading. In asexual populations, these mutations must either arise on the same background or compete against each other. In sexual populations, recombination can…

Populations and Evolution · Quantitative Biology 2013-12-19 D. B. Weissman , O. Hallatschek

We present an explicit solution to a classic model of cell-population growth introduced by Luria and Delbrueck 70 years ago to study the emergence of mutations in bacterial populations. In this model a wild-type population is assumed to…

Probability · Mathematics 2015-06-23 Peter Keller , Tibor Antal

We consider the evolution of populations under the joint action of mutation and differential reproduction, or selection. The population is modelled as a finite-type Markov branching process in continuous time, and the associated…

Populations and Evolution · Quantitative Biology 2009-02-23 Ellen Baake , Hans-Otto Georgii

We consider the Moran model in continuous time with two types, mutation, and selection. We concentrate on the ancestral line and its stationary type distribution. Building on work by Fearnhead (J. Appl. Prob. 39 (2002), 38-54) and Taylor…

Populations and Evolution · Quantitative Biology 2013-12-09 Sandra Kluth , Thiemo Hustedt , Ellen Baake

A new family of continuous distribution is proposed by using Kumaraswamy-G (Cordeiro and de Castro, 2011) distribution as the base line distribution in the Marshal-Olkin (Marshall and Olkin, 1997) construction. A number of known…

Statistics Theory · Mathematics 2016-08-23 Laba Handique , Subrata Chakraborty

If the prior probability distributions of all possible hypothetical true means and all possible observed means of a continuous variable are conditional on the universal set of all numbers (i.e., before the nature of a study is known and a…

Methodology · Statistics 2025-06-05 Huw Llewelyn

In the present work, via computational simulation we study the statistical distribution of people versus number of steps acquired by them in a learning process, considering Darwin classical theory of evolution, i.e. competition, learning…

Statistical Mechanics · Physics 2007-05-23 Hari Mohan Gupta , José Roberto Campanha

Preferential attachment is a popular generative mechanism to explain the widespread observation of power law distributed networks. We introduce an alternative explanation for the phenomenon by allowing the link growth rates to vary across…

Physics and Society · Physics 2007-06-18 Birgitte Freiesleben de Blasio , Odd O Aalen

Within the context of a viable and economical SUSY preon model, two vector--like families $Q_{L,R} = (U,D,N,E)_{L,R}$ and $Q^\prime_{L,R} = (U^\prime,D^\prime,N^\prime,E^\prime)_{L,R}$ with masses of order 1 TeV, one of which is a doublet…

High Energy Physics - Phenomenology · Physics 2007-05-23 H. Stremnitzer

Another new family of continuous probability distribution is proposed by using Generalized Marshal-Olkin distribution as the base line distribution in the Kumaraswamy-G distribution. This family includes (Cordeiro and de Castro, 2011) and…

Statistics Theory · Mathematics 2016-09-16 Laba Handique , Subrata Chakraborty

Many protein systems fold in a two-state manner. Random models, however, rarely display two-state kinetics and thus such behavior should not be accepted as a default. To date, many theories for the prevalence of two-state kinetics have been…

Biological Physics · Physics 2015-06-15 Thomas J. Lane , Christian R. Schwantes , Kyle A. Beauchamp , Vijay S. Pande
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