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The evolutionary processes of complex systems contain critical information regarding their functional characteristics. The generation time of edges provides insights into the historical evolution of various networked complex systems, such…

Artificial Intelligence · Computer Science 2025-01-14 En Xu , Can Rong , Jingtao Ding , Yong Li

Biochemical processes in cells are governed by complex networks of many chemical species interacting stochastically in diverse ways and on different time scales. Constructing microscopically accurate models of such networks is often…

Quantitative Methods · Quantitative Biology 2021-06-09 Catalina Rivera , David Hofmann , Ilya Nemenman

We introduce a unified framework for solving first passage times of time-homogeneous diffusion processes. According to the killed version potential theory and the perturbation theory, we are able to deduce closed-form solutions for…

Probability · Mathematics 2026-01-14 Angelos Dassios , Luting Li

This report will show the history of deep learning evolves. It will trace back as far as the initial belief of connectionism modelling of brain, and come back to look at its early stage realization: neural networks. With the background of…

Machine Learning · Computer Science 2015-11-09 Haohan Wang , Bhiksha Raj

We demonstrate the existence of noise-induced periodicity (coherence resonance) in both a discrete-time model and a continuous-time model of an excitable neuron. In particular, we show that the effects of noise added to the fast and slow…

Neurons and Cognition · Quantitative Biology 2009-11-10 Robert C. Hilborn , Rebecca J. Erwin

The transport of particles in cells is influenced by the properties of intracellular networks they traverse while searching for localized target regions or reaction partners. Moreover, given the rapid turnover in many intracellular…

Biological Physics · Physics 2024-06-21 Lachlan Elam , Mónica C. Quiñones-Frías , Ying Zhang , Avital A. Rodal , Thomas G. Fai

We consider the existence and uniqueness of solutions of an initial-boundary value problem for a coupled system of PDE's arising in a model for Alzheimer's disease. Apart from reaction diffusion equations, the system contains a transport…

Analysis of PDEs · Mathematics 2018-05-15 Michiel Bertsch , Bruno Franchi , Maria Carla Tesi , Andrea Tosin

This paper is an introduction to the membrane potential equation for neurons. Its properties are described, as well as sample applications. Networks of these equations can be used for modeling neuronal systems, which also process images and…

Neurons and Cognition · Quantitative Biology 2018-01-29 Matthias S. Keil

These are lecture notes for various Summer and Winter schools that I have given. The notes describe the methodology called Variational Modelling, and focus on the application to the modelling of gradient-flow systems. I describe the…

Mathematical Physics · Physics 2014-02-11 Mark A. Peletier

The compartmental model is a basic tool for studying signal propagation in neurons, and, if the model parameters are adequately defined, it can also be of help in the study of electrical or fluid transport. Here we show that the input…

Cell Behavior · Quantitative Biology 2007-05-23 E. Louis C. Degli Esposti Boschi G. J. Ortega E. Fernandez

A one-dimensional model on a line of the length L is investigated, which involves particle diffusion as well as single particle annihilation. There are also creation and annihilation at the boundaries. The static and dynamical behaviors of…

Mathematical Physics · Physics 2014-03-17 Mohammad Khorrami , Amir Aghamohammadi

In order to describe the firing activity of a homogenous assembly of neurons, we consider time elapsed models, which give mathematical descriptions of the probability density of neurons structured by the distribution of times elapsed since…

Analysis of PDEs · Mathematics 2016-12-28 S Mischler , Q Weng

Consider a network embedded in the 2D plane, where a particle diffuses along the edges of the network. It is clear that over short length scales a particle moves along a single edge and thus undergoes one-dimensional diffusion. However, on…

Statistical Mechanics · Physics 2021-08-23 D. B. Wilson , C. H. L. Beentjes

Biological visual systems exhibit abundant recurrent connectivity. State-of-the-art neural network models for visual recognition, by contrast, rely heavily or exclusively on feedforward computation. Any finite-time recurrent neural network…

Neurons and Cognition · Quantitative Biology 2020-12-09 Ruben S. van Bergen , Nikolaus Kriegeskorte

We study a model of interacting neurons. The structure of this neural system is composed of two layers of neurons such that the neurons of the first layer send their spikes to the neurons of the second one: if $N$ is the number of neurons…

Probability · Mathematics 2023-06-22 Xavier Erny

The human visual system is an intricate network of brain regions that enables us to recognize the world around us. Despite its abundant lateral and feedback connections, object processing is commonly viewed and studied as a feedforward…

Neurons and Cognition · Quantitative Biology 2019-10-09 Tim C Kietzmann , Courtney J Spoerer , Lynn Sörensen , Radoslaw M Cichy , Olaf Hauk , Nikolaus Kriegeskorte

This paper proposes a time-warping transfer learning method, a technique for temporally rescaling the learned dynamics of a recurrent neural network (RNN) with a Long Short-Term Memory (LSTM) layer to enable task transfer across fuel…

Applications · Statistics 2026-05-12 Jonathon Hirschi , Jan Mandel , Adam Kochanski

We consider a basic one-dimensional model of diffusion which allows to obtain a diversity of diffusive regimes whose speed depends on the moments of the per-site trapping time. This model is closely related to the continuous time random…

Probability · Mathematics 2019-03-08 Elena Floriani , Ricardo Lima , Edgardo Ugalde

Motivated by the dynamics of resonant neurons we discuss the properties of the first passage time (FPT) densities for nonmarkovian differentiable random processes. We start from an exact expression for the FPT density in terms of an…

Data Analysis, Statistics and Probability · Physics 2009-11-11 T. Verechtchaguina , I. M. Sokolov , L. Schimansky-Geier

The elapsed time model has been widely studied in the context of mathematical neuroscience with many open questions left. The model consists of an age-structured equation that describes the dynamics of interacting neurons structured by the…

Analysis of PDEs · Mathematics 2021-03-22 Maria Caceres , Benoît Perthame , Delphine Salort , Nicolas Torres