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Related papers: Mathematical modelling of the cardiovascular syste…

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Numerical model of the peripheral circulation and dynamical model of the large vessels and the heart are discussed in this paper. They combined together into the global model of blood circulation. Some results of numerical simulations…

Biological Physics · Physics 2007-12-31 S. S. Simakov , A. S. Kholodov , A. V. Evdokimov , Y. A. Kholodov

In this article, we review the mathematical modeling for the vascular system.

Tissues and Organs · Quantitative Biology 2021-04-23 Ju Liu , Ingrid S. Lan , Alison L. Marsden

Computational hemodynamics is becoming an increasingly important tool in clinical applications and surgical procedures involving the cardiovascular system. Aim of this review is to provide a compact summary of state of the art 0D-1D…

Medical Physics · Physics 2022-01-03 Stefania Scarsoglio , Luca Ridolfi

The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…

Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

Patient-specific computational models of the heart are powerful tools for cardiovascular research and medicine, with demonstrated applications in treatment planning, device evaluation, and surgical decision-making. Yet constructing such…

Medical Physics · Physics 2026-04-21 Aaron L. Brown , Ju Liu , Daniel B. Ennis , Alison L. Marsden

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

It is well known that in the computational fluid dynamics simulations related to the cardiovascular system the enforcement of outflow boundary conditions is a crucial point. In fact, they highly affect the computed flow and a wrong setup…

Fluid Dynamics · Physics 2025-03-05 Zahra Mirzaiyan , Michele Girfoglio , Gianluigi Rozza

We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…

Numerical Analysis · Mathematics 2022-08-12 Michele Bucelli , Alberto Zingaro , Pasquale Claudio Africa , Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

In this study, we present a comprehensive numerical analysis of blood flow within human left ventricle models, with particular emphasis on optimizing simulation conditions to enhance the realism and computational efficiency of heart flow…

Numerical simulations of real-world phenomena require a computational scheme and a computational domain. In the context of haemodynamics, the computational domain is the blood vessel network through which blood flows. Such networks contain…

Discrete Mathematics · Computer Science 2025-02-19 Jay Aodh Mackenzie , Megan Jeanne Miller , Nicholas Hill , Mette Olufsen

- Modeling Human cardiovascular system is always an important issue. One of the most effective methods is using lumped model to reach to a complete model of human cardiovascular system. Such modeling with advanced considerations is used in…

Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…

Hybrid modeling, the combination of first principle and machine learning models, is an emerging research field that gathers more and more attention. Even if hybrid models produce formidable results for academic examples, there are still…

Machine Learning · Computer Science 2021-12-15 Tobias Thummerer , Johannes Tintenherr , Lars Mikelsons

The introduction of computational models in cardiovascular sciences has been progressively bringing new and unique tools for the investigation of the physiopathology. Together with the dramatic improvement of imaging and measuring devices…

Blood system functions are very diverse and important for most processes in human organism. One of its primary functions is matter transport among different parts of the organism including tissue supplying with oxygen, carbon dioxide…

Biological Physics · Physics 2007-12-31 A. S. Kholodov , S. S. Simakov , Y. A. Kholodov , A. A. Nadolsky , A. N. Shushlebin

We present a novel mathematical model that simulates myocardial blood perfusion by embedding multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, reduced valve…

Computational Engineering, Finance, and Science · Computer Science 2023-03-27 Alberto Zingaro , Christian Vergara , Luca Dede' , Francesco Regazzoni , Alfio Quarteroni

Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk…

Tissues and Organs · Quantitative Biology 2015-10-08 Andrew Parton , Victoria McGilligan , Maurice OKane , Francina R Baldrick , Steven Watterson

Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…

Soft Condensed Matter · Physics 2015-03-17 Florian Janoschek , Federico Toschi , Jens Harting

Whole-body hemodynamics simulators, which model blood flow and pressure waveforms as functions of physiological parameters, are now essential tools for studying cardiovascular systems. However, solving the corresponding inverse problem of…

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