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Transcranial ultrasound therapy uses focused acoustic energy to induce therapeutic bioeffects in the brain. Ultrasound must be transmitted through the skull, which is highly attenuating and heterogeneous, causing beam distortion, reducing…

Simulation involves predicting responses of a physical system. In this article, we simulate opto-acoustic signals generated in a three-dimensional volume due to absorption of an optical pulse. A separable computational model is developed…

Computational Physics · Physics 2021-07-22 Jason Zalev , Michael C. Kolios

Scalable and efficient numerical simulations continue to gain importance, as computation is firmly established as the third pillar of discovery, alongside theory and experiment. Meanwhile, the performance of computing hardware grows through…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-26 Pietro Incardona , Antonio Leo , Yaroslav Zaluzhnyi , Rajesh Ramaswamy , Ivo F. Sbalzarini

We present a novel immersed boundary method that implements acoustic perturbation theory to model an acoustically levitated droplet. Instead of resolving sound waves numerically, our hybrid method solves acoustic scattering…

Soft Condensed Matter · Physics 2024-03-22 Jacqueline B. Sustiel , David G. Grier

The Coherent Multiplex is formalized and validated as a scalable, real-time system for identifying, analyzing, and visualizing coherence among multiple time series. Its architecture comprises a fast spectral similarity layer based on cosine…

Signal Processing · Electrical Eng. & Systems 2025-08-28 Noah Shore

The cochlea, the auditory part of the inner ear, is a spiral-shaped organ with large morphological variability. An individualized assessment of its shape is essential for clinical applications related to tonotopy and cochlear implantation.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Wilhelm Wimmer , Clair Vandersteen , Nicolas Guevara , Marco Caversaccio , Hervé Delingette

In this article we propose and numerically implement a mathematical model for the simulation of three-dimensional semiconductor devices characterized by an heterogeneous material structure. The model consists of a system of nonlinearly…

Numerical Analysis · Mathematics 2013-07-12 A. Mauri , R. Sacco , M. Verri

Objective: In cochlear implant users with residual acoustic hearing, compound action potentials (CAPs) can be evoked by acoustic (aCAP) or electric (eCAP) stimulation and recorded through the electrodes of the implant. We propose a novel…

Medical Physics · Physics 2024-10-28 Daniel Kipping , Yixuan Zhang , Waldo Nogueira

The cochlea is our fluid-filled organ of hearing with a unique spiral shape. The physiological role of this shape remains unclear. Previous research has paid only little attention to the occurrence of transverse flow in the cochlea, in…

The imitation of percussive sounds via the human voice is a natural and effective tool for communicating rhythmic ideas on the fly. Thus, the automatic retrieval of drum sounds using vocal percussion can help artists prototype drum patterns…

Sound · Computer Science 2021-10-19 Alejandro Delgado , SkoT McDonald , Ning Xu , Charalampos Saitis , Mark Sandler

This paper presents a general and robust method for the fluid-structure interaction of membranes and shells undergoing large displacement and large added-mass effects by coupling an immersed-boundary method with a shell finite-element…

Fluid Dynamics · Physics 2023-08-15 Marin Lauber , Gabriel D. Weymouth , Georges Limbert

Building upon our earlier passive models for the cochlea, here we enhance the model with an active mechanism. Starting with a one-chamber simplification leading to a system of a time-dependent PDE in two spatial variables for the pressure…

Analysis of PDEs · Mathematics 2020-08-12 Jacob Rubinstein , Peter Sternberg

The aim of this paper is to understand the behaviour of a large number of coupled subwavelength resonators. We use layer potential techniques in combination with numerical computations to study the acoustic pressure field due to scattering…

Analysis of PDEs · Mathematics 2019-10-03 Habib Ammari , Bryn Davies

We consider a multiscale approach based on immersed methods for the efficient computational modeling of tissues composed of an elastic matrix (in two or three-dimensions) and a thin vascular structure (treated as a co-dimension two…

Numerical Analysis · Mathematics 2021-11-18 Luca Heltai , Alfonso Caiazzo

Context. Recent, nonlinear simulations of wave generation and propagation in full-star models have been carried out in the anelastic approximation using spectral methods. Although it makes long time steps possible, this approach excludes…

Solar and Stellar Astrophysics · Physics 2020-09-15 L. Horst , P. V. F. Edelmann , R. Andrassy , F. K. Roepke , D. M. Bowman , C. Aerts , R. P. Ratnasingam

We review a scalable two- and three-dimensional computer code for low-temperature plasma simulations in multi-material complex geometries. Our approach is based on embedded boundary (EB) finite volume discretizations of the minimal…

Computational Physics · Physics 2019-05-01 Robert Marskar

The immersed boundary method is a mathematical formulation and numerical method for solving fluid-structure interaction problems. For many biological problems, such as models that include the cell membrane, the immersed structure is a…

Numerical Analysis · Mathematics 2018-06-07 Ondrej Maxian , Andrew T. Kassen , Wanda Strychalski

The formation of shear shock waves in the brain has been proposed as one of the plausible explanations for deep intracranial injuries. In fact, such singular solutions emerge naturally in soft viscoelastic tissues under dynamic loading…

Soft Condensed Matter · Physics 2025-02-05 Harold Berjamin

Computational and human perception are often considered separate approaches for studying sound changes over time; few works have touched on the intersection of both. To fill this research gap, we provide a pioneering review contrasting…

Computation and Language · Computer Science 2024-07-09 Siqi He , Wei Zhao

This study introduces a biologically-inspired model designed to examine the role of coincidence detection cells in speech segregation tasks. The model consists of three stages: a time-domain cochlear model that generates instantaneous rates…

Neurons and Cognition · Quantitative Biology 2024-05-13 Asaf Zorea , Miriam Furst