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Related papers: Energy landscapes and rare events

200 papers

Recent studies of concentrated solid solutions have highlighted the role of varied solute interactions in the determination of a wide variety of mesoscale properties. These solute interactions emerge as spatial fluctuations in potential…

Materials Science · Physics 2025-09-18 Ritesh Jagatramka , Chu Wang , Matthew Daly

In recent years single molecule force spectroscopy has opened a new avenue to provide profiles of the complex energy landscape of biomolecules. In this field, quantitative analyses of the data employing sound theoretical models, have played…

Biomolecules · Quantitative Biology 2015-01-15 Changbong Hyeon , Michael Hinczewski , D. Thirumalai

The dynamics of biological polymers, including proteins, RNA, and DNA, occur in very high-dimensional spaces. Many naturally-occurring polymers can navigate a vast phase space and rapidly find their lowest free energy (folded) state. Thus,…

Computational Physics · Physics 2024-06-19 Frederico Campos Freitas , Sandra Byju , Asem Hassan , Ronaldo Junio de Oliveira , Paul C. Whitford

Many enhanced sampling techniques rely on the identification of a number of collective variables that describe all the slow modes of the system. By constructing a bias potential in this reduced space one is then able to sample efficiently…

Computational Physics · Physics 2019-03-05 Michele Invernizzi , Michele Parrinello

Systems with a complex dynamics like glasses or models of biological evolution are often pictured in terms of complex landscapes, with a large number of possible collective states. We show on the example of a stochastic spin model with…

Disordered Systems and Neural Networks · Physics 2026-02-03 Laura Guislain , Eric Bertin

We introduce a class of $n$-dimensional (possibly inhomogeneous) spin-like lattice systems presenting modulated phases with possibly different textures. Such systems can be parameterized according to the number of ground states, and can be…

Statistical Mechanics · Physics 2021-06-11 Andrea Braides , Marco Cicalese

A phenomenological free energy model is proposed to describe the behavior of smectic liquid crystals, an intermediate phase that exhibits orientational order and layering at the molecular scale. Advantageous properties render the functional…

Soft Condensed Matter · Physics 2021-05-05 Jingmin Xia , Scott MacLachlan , Timothy J. Atherton , Patrick E. Farrell

The gap in statistics between multi-variate and time-series analysis can be bridged by using entropy statistics and recent developments in multi-dimensional scaling. For explaining the evolution of the sciences as non-linear dynamics, the…

Digital Libraries · Computer Science 2012-11-13 Loet Leydesdorff

Global climate change, extreme climate events, earthquakes and their accompanying natural disasters pose significant risks to humanity. Yet due to the nonlinear feedbacks, strategic interactions and complex structure of the Earth system,…

In the field of quantum chaos, the study of energy levels plays an important role. The aim of this review paper is to critically discuss some of the main contributions regarding the connection between classical dynamics, semi-classical…

Materials Science · Physics 2009-10-31 V. R. Manfredi , L. Salasnich

We use energy landscape methods to investigate the response of a supercooled liquid to random pinning. We classify the structural similarity of different energy minima using a measure of overlap. This analysis reveals a correspondence…

Statistical Mechanics · Physics 2019-01-18 S. P. Niblett , V. K. de Souza , R. L. Jack , D. J Wales

Many systems in biology, physics and engineering can be described by systems of ordinary differential equation containing many parameters. When studying the dynamic behavior of these large, nonlinear systems, it is useful to identify and…

Molecular Networks · Quantitative Biology 2016-04-13 Heather A. Harrington , Dhagash Mehta , Helen M. Byrne , Jonathan D. Hauenstein

Although networks provide a powerful approach to study a large variety of ecological systems, their formulation does not typically account for multiple interaction types, interactions that vary in space and time, and interconnected systems…

Quantitative Methods · Quantitative Biology 2017-03-27 Shai Pilosof , Mason A. Porter , Mercedes Pascual , Sonia Kéfi

With increased access to data and the advent of computers, the use of statistical tools and numerical simulations is becoming commonplace for ecologists. These approaches help improve our understanding of ecological phenomena and their…

Other Quantitative Biology · Quantitative Biology 2025-04-08 Maxime Clenet , Maxime Dion , F. Guillaume Blanchet

The knowledge of the Free Energy Landscape topology is the essential key to understand many biochemical processes. The determination of the conformers of a protein and their basins of attraction takes a central role for studying molecular…

Biomolecules · Quantitative Biology 2009-06-26 Diego Prada-Gracia , Jesus Gomez-Gardenes , Pablo Echenique , Fernando Falo

To analyze high-dimensional systems, many fields in science and engineering rely on high-level descriptions, sometimes called "macrostates," "coarse-grainings," or "effective theories". Examples of such descriptions include the…

Information Theory · Computer Science 2015-06-19 David H. Wolpert , Joshua A. Grochow , Eric Libby , Simon DeDeo

Much of the information about the multi-valley structure of disordered spin systems can be convened in a simple tree structure -- a barrier tree -- the leaves and internal nodes of which represent, respectively, the local minima and the…

Disordered Systems and Neural Networks · Physics 2009-11-10 Wim Hordijk , Jose F. Fontanari , Peter F. Stadler

Scientific research in many fields routinely requires the analysis of large datasets, and scientists often employ workflow systems to leverage clusters of computers for their data analysis. However, due to their size and scale, these…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-05 Lauritz Thamsen , Yehia Elkhatib , Paul Harvey , Syed Waqar Nabi , Jeremy Singer , Wim Vanderbauwhede

In years to come, we shall see substantial progress in our understanding of nuclear structure - a rich and many-faceted field. An important element in this task will be to extend the study of nuclei into new domains. The journey to 'the…

Nuclear Theory · Physics 2008-11-26 Jacek Dobaczewski , Witold Nazarewicz

Depth, number, and shape of the basins of the potential energy landscape are the key ingredients of the inherent structure thermodynamic formalism introduced by Stillinger and Weber [F. H. Stillinger and T. A. Weber, Phys. Rev. A 25, 978…

Soft Condensed Matter · Physics 2009-11-07 Emilia La Nave , Stefano Mossa , Francesco Sciortino