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Diffuse optical tomography (DOT) utilises near-infrared light for imaging spatially distributed optical parameters, typically the absorption and scattering coefficients. The image reconstruction problem of DOT is an ill-posed inverse…

Computational Physics · Physics 2021-12-15 Meghdoot Mozumder , Andreas Hauptmann , Ilkka Nissilä , Simon R. Arridge , Tanja Tarvainen

Light scattering imposes a major obstacle for imaging objects seated deeply in turbid media, such as biological tissues and foggy air. Diffuse optical tomography (DOT) tackles scattering by volumetrically recovering the optical absorbance…

When the inverse problem of diffuse optical tomography (DOT) is solved with the Born or Rytov approximation, the size of the matrix of the linear inverse problem becomes large if the volume (or area) of the domain in biological tissue used…

Medical Physics · Physics 2021-07-22 Tetsuya Mimura , Yu Jiang , Norikazu Todoroki , Manabu Machida

Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Yongyi Zhao , Ankit Raghuram , Hyun K. Kim , Andreas H. Hielscher , Jacob T. Robinson , Ashok Veeraraghavan

This paper addresses the inverse obstacle scattering problem of simultaneously reconstructing the obstacle geometry and boundary conditions from multi-frequency near-field backscattering data. We first establish rigorous high-frequency…

Analysis of PDEs · Mathematics 2026-04-14 Jialei Li , Xiaodong Liu

Medical imaging is nowadays a pillar in diagnostics and therapeutic follow-up. Current research tries to integrate established - but ionizing - tomographic techniques with technologies offering reduced radiation exposure. Diffuse Optical…

Numerical Analysis · Mathematics 2024-02-15 Alessandro Benfenati , Paola Causin , Martina Quinteri

Diffuse optical breast imaging utilizes near-infrared (NIR) light propagation through tissues to assess the optical properties of tissue for the identification of abnormal tissue. This optical imaging approach is sensitive, cost-effective,…

Medical Physics · Physics 2017-11-22 Wenxiang Cong , Xavier Intes , Ge Wang

In this paper, we study the mathematical imaging problem of diffraction tomography (DT), which is an inverse scattering technique used to find material properties of an object by illuminating it with probing waves and recording the…

Numerical Analysis · Mathematics 2023-05-16 Florian Faucher , Clemens Kirisits , Michael Quellmalz , Otmar Scherzer , Eric Setterqvist

Diffuse optical tomography (DOT) has been investigated as an alternative imaging modality for breast cancer detection thanks to its excellent contrast to hemoglobin oxidization level. However, due to the complicated non-linear photon…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Jaejun Yoo , Sohail Sabir , Duchang Heo , Kee Hyun Kim , Abdul Wahab , Yoonseok Choi , Seul-I Lee , Eun Young Chae , Hak Hee Kim , Young Min Bae , Young-wook Choi , Seungryong Cho , Jong Chul Ye

Inverse boundary value problems for the radiative transport equation play important roles in optics-based medical imaging techniques such as diffuse optical tomography (DOT) and fluorescence optical tomography (FOT). Despite the rapid…

Numerical Analysis · Mathematics 2015-06-19 Tian Ding , Kui Ren

The Diffuse Optical Tomography (DOT) has received considerable attention in the recent years in the field of biomedical imaging and disease detection. However, imaging through highly diffusive medium is a challenge and stability is always…

Image and Video Processing · Electrical Eng. & Systems 2020-03-31 Tapan Das , P. K. Dutta

The inverse scattering problem is of critical importance in a number of fields, including medical imaging, sonar, sensing, non-destructive evaluation, and several others. The problem of interest can vary from detecting the shape to the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Doga Dikbayir , Abdel Alsnayyan , Vishnu Naresh Boddeti , Balasubramaniam Shanker , Hasan Metin Aktulga

The stochastic differential and integral equations describing the system of particles weakly interacting among themselves which are absorbed and scattered by particles of a medium are considered. The time-dependent transport equation with…

Mathematical Physics · Physics 2010-03-15 Igor Kharin

In optical diffraction tomography (ODT), the three-dimensional scattering potential of a microscopic object rotating around its center is recovered by a series of illuminations with coherent light. Reconstruction algorithms such as the…

Numerical Analysis · Mathematics 2022-09-02 Robert Beinert , Michael Quellmalz

In the reconstruction process of unknown multiple scattering objects in inverse medium scattering problems, the first important step is to effectively locate some approximate domains that contain all inhomogeneous media. Without such an…

Numerical Analysis · Mathematics 2015-06-12 Keji Liu , Jun Zou

The image reconstruction of chromophore concentrations using Diffuse Optical Tomography (DOT) data can be described mathematically as an ill-posed inverse problem. Recent work has shown that the use of hyperspectral DOT data, as opposed to…

Numerical Analysis · Mathematics 2014-10-16 Arvind K. Saibaba , Misha Kilmer , Eric Miller , Sergio Fantini

Nonlinear parametric inverse problems appear in many applications. Here, we focus on diffuse optical tomography (DOT) in medical imaging to recover unknown images of interest, such as cancerous tissue in a given medium, using a mathematical…

Numerical Analysis · Mathematics 2020-07-14 Selin Aslan , Eric de Sturler , Serkan Gugercin

Diffuse Optical Tomography (DOT) is an emerging technology in medical imaging which employs light in the NIR spectrum to estimate the distribution of optical coefficients in biological tissues for diagnostic and monitoring purposes. DOT…

Numerical Analysis · Mathematics 2022-05-27 Alessandro Benfenati , Giuseppe Bisazza , Paola Causin

The inverse problem we consider is to reconstruct the location and shape of buried obstacles in the lower half-space of an unbounded two-layered medium in two dimensions from phaseless far-field data. A main difficulty of this problem is…

Numerical Analysis · Mathematics 2021-05-26 Long Li , Jiansheng Yang , Bo Zhang , Haiwen Zhang

This work presents GS-DOT, a novel image reconstruction framework based on Gaussian Splatting (GS) for diffuse optical tomography (DOT). Inspired by GS for rendering applications, absorption coefficients are represented as a sparse sum of…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Jingjing Jiang
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