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Cancer results from a sequence of genetic and epigenetic changes which lead to a variety of abnormal phenotypes including increased proliferation and survival of somatic cells, and thus, to a selective advantage of pre-cancerous cells. The…

Populations and Evolution · Quantitative Biology 2011-12-05 Erik A. Martens , R. Kostadinov , Carlo C. Maley , Oskar Hallatschek

Changing environmental conditions can significantly affect the dynamics of disease spread. These changes may arise naturally or result from human interventions; in the latter case, lockdown measures that lead to abrupt but temporary…

Statistical Mechanics · Physics 2026-05-29 Elad Korngut , Michael Assaf

In this paper crack initiation, propagation and branching phenomena are simulated using the Pseudo-Spring Smooth Particle Hydrodynamics (SPH) in two and three-dimensional domains. The pseudo-spring analogy is used to model material damage.…

Computational Engineering, Finance, and Science · Computer Science 2019-05-09 Md Rushdie Ibne Islam , Amit Shaw

The sustainable use of multicomponent treatments such as combination therapies, combination vaccines/chemicals, and plants carrying multigenic resistance requires an understanding of how their population-wide deployment affects the speed of…

Populations and Evolution · Quantitative Biology 2015-06-16 Romain Bourget , Loïc Chaumont , Natalia Sapoukhina

The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a…

Physics and Society · Physics 2018-04-05 Rosanna C Barnard , Istvan Z Kiss , Luc Berthouze , Joel C Miller

Non-terminal events can represent a meaningful change in a patient's life. Thus, better understanding and predicting their occurrence can bring valuable information to individuals. In a context where longitudinal markers could inform these…

Methodology · Statistics 2025-01-16 Juliette Ortholand , Stanley Durrleman , Sophie Tezenas du Montcel

Dynamical phenomena such as infectious diseases are often investigated by following up subjects longitudinally, thus generating time to event data. The spatial aspect of such data is also of primordial importance, as many infectious…

Methodology · Statistics 2020-10-13 Ajmal Oodally , Estelle Kuhn , Klara Goethals , Luc Duchateau

Modeling long-range epidemic spreading in a random environment, we consider a quenched disordered, $d$-dimensional contact process with infection rates decaying with the distance as $1/r^{d+\sigma}$. We study the dynamical behavior of the…

Disordered Systems and Neural Networks · Physics 2015-04-02 R. Juhász , I. A. Kovács , F. Iglói

The spread of an epidemic process is considered in the context of a spatial SIR stochastic model that includes a parameter $0\le p\le 1$ that assigns weights $p$ and $1- p$ to global and local infective contacts respectively. The model was…

Populations and Evolution · Quantitative Biology 2020-01-29 Gabriel Fabricius , Alberto Maltz

Given an endogenous timescale set by invasion in a constant environment, we introduced periodic temporal variation in competitive superiority by alternating the species' propagation rates. By manipulating habitat size and introduction rate,…

Populations and Evolution · Quantitative Biology 2011-05-10 Lauren O'Malley , G. Korniss , Sai Satya Praveen Mungara , Thomas Caraco

We consider an epidemic model of SIR type set on a homogeneous tree and investigate the spreading properties of the epidemic as a function of the degree of the tree, the intrinsic basic reproduction number and the strength of the…

Analysis of PDEs · Mathematics 2021-06-09 Christophe Besse , Grégory Faye

In the studies of plant infections, the plant immune response is known to play an essential role. In this paper we derive and analyse a new mathematical model of plant immune response with particular account for post-transcriptional gene…

Chaotic Dynamics · Physics 2015-11-18 G. Neofytou , Y. N. Kyrychko , K. B. Blyuss

We consider a stochastic susceptible-infected-recovered (SIR) model with contact tracing on random trees and on the configuration model. On a rooted tree, where initially all individuals are susceptible apart from the root which is…

Populations and Evolution · Quantitative Biology 2020-02-25 Augustine Okolie , Johannes Müller

Infectious diseases are practically represented by models with multiple states and complex transition rules corresponding to, for example, birth, death, infection, recovery, disease progression, and quarantine. In addition, networks…

Disordered Systems and Neural Networks · Physics 2007-05-23 Naoki Masuda , Norio Konno

The study of infectious disease epidemiology for multi-type disease pathogens requires modelling techniques that account for the complex interactions existing between strains across geography and time. In this paper, we propose a novel…

Methodology · Statistics 2026-05-06 Matthew Adeoye , Simon E. F. Spencer , Xavier Didelot

We present an SI epidemic model whereby a continuous variable captures variability in proliferative potential and resistance to infection among susceptibles. The occurrence of heritable, spontaneous changes in these phenotype and the…

Populations and Evolution · Quantitative Biology 2021-12-30 Tommaso Lorenzi , Andrea Pugliese , Mattia Sensi , Agnese Zardini

We propose an extension of the classical susceptible infectious recovered (SIR) model that incorporates the effects of spatial propagation of an epidemic through a small number of additional compartments. The model is designed to capture…

Numerical Analysis · Mathematics 2026-03-02 M. Soledad Aronna , Mariana Bergonzi , Ernesto Kofman

We introduce a model of the diffusion of an epidemic with demographically heterogeneous agents interacting socially on a spatially structured network. Contagion-risk averse agents respond behaviorally to the diffusion of the infections by…

General Economics · Economics 2022-04-13 Alberto Bisin , Andrea Moro

The study of epidemic models plays an important role in mathematical epidemiology. There are many researches on epidemic models using ordinary differential equations, partial differential equations or stochastic differential equations. In…

Probability · Mathematics 2023-03-10 Yuqi Li , Lihua Zhang

We are interested in the invasion phase for stochastic processes with interactions when a single mutant with positive fitness arrives in a resident population at equilibrium. By a now classic approach, the first stage of the invasion is…

Probability · Mathematics 2024-06-14 Vincent Bansaye , Xavier Erny , Sylvie Méléard