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We review physical motivations and possible realizations of string vacua with large internal volume and/or low string scale and discuss the issue of supersymmetry breaking. In particular, we describe the key features of Scherk-Schwarz…

Generic D-brane string models of particle physics predict the existence of extra U(1) gauge symmetries beyond hypercharge. These symmetries are not of the E_6 class but rather include the gauging of Baryon and Lepton numbers as well as…

Recently a class of Type IIA orientifold models was constructed yielding just the fermions of the SM at the intersections of D6-branes wrapping a 6-torus. We generalize that construction to the case of Type IIB compactified on an…

We propose a bottom-up approach to the building of particle physics models from string theory. Our building blocks are Type II D-branes which we combine appropriately to reproduce desirable features of a particle theory model: 1) Chirality…

We argue that tachyon-free type I string vacua with supersymmetry breaking in the open sector at the string scale can be interpreted, via S and T-duality arguments, as metastable vacua of supersymmetric type I superstring. The dynamics of…

We review some aspects of the dramatic consequences of supersymmetry breaking on string vacua. In particular, we focus on the issue of vacuum stability in ten-dimensional string models with broken, or without, supersymmetry, whose…

I describe the main features of new intersecting D4- and D5-brane orbifold models that yield the non-supersymmetric standard model, up to vector-like matter and, in some cases, extra U(1) factors in the gauge group. There are six-stack…

We study a system of intersecting NS and D-branes in type IIA string theory in R^{9,1}. We show that the 3+1 dimensional non-supersymmetric theory at the intersection has unstable vacua which are long-lived in some regions of the parameter…

Intersecting Dp-branes often give rise to chiral fermions living on their intersections. We study the construction of four-dimensional chiral gauge theories by considering configurations of type II D(3+n)-branes wrapped on non-trivial…

We construct four dimensional three generation non-supersymmetric $SU(3)_c \times SU(2)_L \times U(1)_Y$ intersecting D6-brane models with $\nu_R$\rq{s}. At three stacks we find exactly the MSSM chiral fermion matter spectrum. At 4-,…

We propose a unified framework within Type IIA string theory, based on a globally consistent intersecting D6-brane model compactified on a $T^6/(\mathbb{Z}_2 \times \mathbb{Z}_2)$ orientifold. The model realizes the MSSM-like spectrum…

Type IIB superstring models with the standard model gauge group on D3-branes and with massless matter associated with open strings joining D3-branes to D3-branes or D3-branes to ${\rm D}7_3$-branes are studied. Models with gauge coupling…

We show how to construct chiral tachyon-free perturbative orientifold models, where supersymmetry is broken at the string scale on a collection of branes while, to lowest order, the bulk and the other branes are supersymmetric. In higher…

We construct new semi-realistic Type IIB flux vacua on $Z_2\times Z_2$ orientifolds with three- and four- Standard Model (SM) families and up to three units of quantized flux. The open-string sector is comprised of magnetized D-branes and…

We perform a systematic study of the Standard Model embedding in a D-brane configuration of type I string theory at the TeV scale. We end up with an attractive model and we study several phenomenological questions, such as gauge coupling…

We construct the first globally consistent semi-realistic Type I string vacua on an elliptically fibered manifold where the zero modes of the Euclidean D1-instanton sector allow for the generation of non-perturbative Majorana masses of an…

Dynamical supersymmetry breaking in a long-lived meta-stable vacuum is a phenomenologically viable possibility. This relatively unexplored avenue leads to many new models of dynamical supersymmetry breaking. Here, we present a surprisingly…

We point out that type I string theory in the presence of internal magnetic fields provides a concrete realization of split supersymmetry. To lowest order, gauginos are massless while squarks and sleptons are superheavy. We build such…

The state of the art in D-brane model building is briefly reviewed, focusing on recent achievements in the construction of D=4 N = 1 type II string vacua with semi-realistic gauge sectors. Such progress relies on a better understanding of…

We study the existence of long-lived meta-stable supersymmetry breaking vacua in gauge theories with massless quarks, upon the addition of extra massive flavors. A simple realization is provided by a modified version of SQCD with N_{f,0} <…