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Knowledge-based biomedical data science (KBDS) involves the design and implementation of computer systems that act as if they knew about biomedicine. Such systems depend on formally represented knowledge in computer systems, often in the…

Artificial Intelligence · Computer Science 2022-09-13 Tiffany J. Callahan , Harrison Pielke-Lombardo , Ignacio J. Tripodi , Lawrence E. Hunter

The aim of this article is to present an overview of the existing biomedical data warehouses and to discuss the issues and future trends in this area. We illustrate this topic by presenting the design of an innovative, complex data…

Databases · Computer Science 2017-01-30 Jérôme Darmont , Emerson Olivier

Data tables in the form of spreadsheets or delimited text files are the most utilised data format in Systems Biology. However, they are often not sufficiently structured and lack clear naming conventions that would be required for…

Molecular Networks · Quantitative Biology 2015-09-30 Wolfram Liebermeister , Timo Lubitz , Jens Hahn

The rapid growth of Large Language Models (LLMs) and AI-driven applications has propelled Vector Database Management Systems (VDBMSs) into the spotlight as a critical infrastructure component. VDBMS specializes in storing, indexing, and…

Software Engineering · Computer Science 2025-03-03 Shenao Wang , Yanjie Zhao , Yinglin Xie , Zhao Liu , Xinyi Hou , Quanchen Zou , Haoyu Wang

Over the past decade there has been a significant growth in bioinformatics databases, tools and resources. Although, bioinformatics is becoming more specific, increasing the number of bioinformatics-wares has made it difficult for…

In today world, organizations like Google, Yahoo, Amazon, Facebook etc. are facing drastic increase in data. This leads to the problem of capturing, storing, managing and analyzing terabytes or petabytes of data, stored in multiple formats,…

Databases · Computer Science 2014-02-07 Mohit Kumar Gupta , Vishal Verma , Megha Singh Verma

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…

Databases · Computer Science 2025-09-22 Rosalia Moreddu

Relational databases play a central role in many information systems. Their schema contains structural (e.g. tables and columns) and behavioral (e.g. stored procedures or views) entity descriptions. Then, just like for ``normal'' software,…

Software Engineering · Computer Science 2024-04-15 Anne Etien , Nicolas Anquetil

Traditional DBMSs execute user- or application-provided SQL queries over relational data with strong semantic guarantees and advanced query optimization, but writing complex SQL is hard and focuses only on structured tables. Contemporary…

Databases · Computer Science 2025-12-15 Guorui Xiao , Enhao Zhang , Nicole Sullivan , Will Hansen , Magdalena Balazinska

The intensive need of atomic data is expanding continuously in a wide variety of applications (e.g. fusion energy and astrophysics, laser-produced, plasma researches, and plasma processing).This paper will introduce our ongoing research…

Atomic Physics · Physics 2012-06-06 Amani Tahat , Wa'el Salah

Database system architectures are undergoing revolutionary changes. Algorithms and data are being unified by integrating programming languages with the database system. This gives an extensible object-relational system where non-procedural…

Databases · Computer Science 2007-05-23 Jim Gray

Researchers in biomedical research, public health, and the life sciences often spend weeks or months discovering, accessing, curating, and integrating data from disparate sources, significantly delaying the onset of actual analysis and…

Modern applications demand high performance and cost efficient database management systems (DBMSs). Their workloads may be diverse, ranging from online transaction processing to analytics and decision support. The cloud infrastructure…

The aim of this paper is to carry out a systematic analysis of the literature to show the state of the art of Business Processes Management Systems (BPMS). BPMS represents a technology that automates business processes connecting users with…

General Economics · Economics 2023-12-04 Alicia Martin-Navarro , Maria Paula Lechuga Sancho , Jose Aurelio Medina-Garrido

Variability inherently exists in databases in various contexts which creates database variants. For example, variants of a database could have different schemas/content (database evolution problem), variants of a database could root from…

Databases · Computer Science 2019-11-27 Parisa Ataei , Qiaoran Li , Eric Walkingshaw , Arash Termehchy

AsterixDB is a new, full-function BDMS (Big Data Management System) with a feature set that distinguishes it from other platforms in today's open source Big Data ecosystem. Its features make it well-suited to applications like web data…

Bioinformatics research is characterized by voluminous and incremental datasets and complex data analytics methods. The machine learning methods used in bioinformatics are iterative and parallel. These methods can be scaled to handle big…

Computational Engineering, Finance, and Science · Computer Science 2015-06-17 Hirak Kashyap , Hasin Afzal Ahmed , Nazrul Hoque , Swarup Roy , Dhruba Kumar Bhattacharyya

A key goal of bioinformatics is to create database systems and software platforms capable of storing and analysing large sets of biological data. Hundreds of biological databases are now available and provide access to huge amount of…

The relational DBMS (RDBMS) has been widely used since it supports various high-level functionalities such as SQL, schemas, indexes, and transactions that do not exist in the O/S file system. But, a recent advent of big data technology…

Databases · Computer Science 2014-06-03 Jun-Sung Kim , Kyu-Young Whang , Hyuk-Yoon Kwon , Il-Yeol Song

Distributed software systems that are designed to run over workstation machines within organisations are termed workstation-based. Workstation-based systems are characterised by dynamically changing sets of machines that are used primarily…

Databases · Computer Science 2012-07-23 Angus Macdonald