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Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…
Predicting interactions between small molecules and proteins is a crucial ingredient of the drug discovery process. In particular, accurate predictive models are increasingly used to preselect potential lead compounds from large molecule…
Critical infrastructure systems like power grid require an improved critical in-formation infrastructure (CII) that can not only help in monitoring of the crit-ical entities but also take part in failure analysis and self-healing. Efficient…
The power grid is a critical infrastructure that allows for the efficient and robust generation, transmission, delivery and consumption of electricity. In the recent years, the physical components have been equipped with computing and…
The remarkable success of foundation models has been driven by scaling laws, demonstrating that model performance improves predictably with increased training data and model size. However, this scaling trajectory faces two critical…
Providing an appropriate level of accessibility to and tracking of data or process elements in large volumes of medical data, is an essential requirement in the Big Data era. Researchers require systems that provide traceability of…
Antibody therapeutics has been extensively studied in drug discovery and development within the past decades. One increasingly popular focus in the antibody discovery pipeline is the optimization step for therapeutic leads. Both traditional…
The advances in data, computing and networking over the last two decades led to a shift in many application domains that includes machine learning on big data as a part of the scientific process, requiring new capabilities for integrated…
Kinase-targeted drug design is challenging. It requires designing inhibitors that can bind to specific kinases when all kinase catalytic domains share a common folding scaffold that binds ATP. Thus, obtaining the desired selectivity, given…
The largest collection of medical evidence in the world is PubMed. However, the significant barrier in accessing and extracting information is information organization. A factor that contributes towards this barrier is managing medical…
Urinary tract infection (UTI) flare-ups pose a significant health risk for older adults with chronic conditions. These infections often go unnoticed until they become severe, making early detection through innovative smart home technologies…
Training frontier-scale foundation models involves coordinating tens of thousands of GPUs over multi-month runs, where even minor performance degradations can accumulate into substantial efficiency losses. Existing health-check mechanisms,…
Deep learning research has generated widespread interest leading to emergence of a large variety of technological innovations and applications. As significant proportion of deep learning research focuses on vision based applications, there…
We propose a coarse-grained theoretical model to capture the aging of microfluidic devices under different conditions including constant applied flow rate and constant applied pressure gradient. Microfluidic devices that sort cells by their…
Most of the services viewed in context to grid and cloud computing are mostly confined to services that are available for intellectual purposes. The grid or cloud computing are large scale distributed systems. The essence of large scale…
Parallel processing, the core of High Performance Computing (HPC), was and still the most effective way in improving the speed of computer systems. For the past few years, the substantial developments in the computing power of processors…
On the Optimizing of Wireless Networks and toward improving the future 5th Generation mobile Network Infrastructure, we propose a novel infrastructure that can be the next Smart City Network. Our proposed Infrastructure takes into…
Grid Computing is an idea of a new kind of network technology in which research work in progress. There is a great deal of hype in this technology based area for that reason it is getting a great deal of attention of the computing…
The use of an automatic system for the analysis of mammographic images has proven to be very useful to radiologists in the investigation of breast cancer, especially in the framework of mammographic-screening programs. A breast neoplasia is…
Cloud computing enables cost-effective on-demand network access to a shared pool of configurable computing resources. The purpose of this paper is to examine and identifying the use of Cloud computing in the critical infrastructure domain…