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Algorithmic self-assembly, a generalization of crystal growth processes, has been proposed as a mechanism for autonomous DNA computation and for bottom-up fabrication of complex nanostructures. A `program' for growing a desired structure…

Materials Science · Physics 2010-01-08 Rebecca Schulman , Erik Winfree

We prove a negative result on the power of a model of algorithmic self-assembly for which it has been notoriously difficult to find general techniques and results. Specifically, we prove that Winfree's abstract Tile Assembly Model, when…

Computational Complexity · Computer Science 2013-04-11 Pierre-Étienne Meunier , Matthew J. Patitz , Scott M. Summers , Guillaume Theyssier , Andrew Winslow , Damien Woods

Working in Winfree's abstract tile assembly model, we show that a constant-size tile assembly system can be programmed through relative tile concentrations to build an n x n square with high probability, for any sufficiently large n. This…

Computational Complexity · Computer Science 2015-03-13 David Doty

We prove that if a set $X \subseteq \Z^2$ weakly self-assembles at temperature 1 in a deterministic tile assembly system satisfying a natural condition known as \emph{pumpability}, then $X$ is a finite union of semi-doubly periodic sets.…

Discrete Mathematics · Computer Science 2009-03-12 David Doty , Matthew J Patitz , Scott M Summers

In the abstract Tile Assembly Model, self-assembling systems consisting of tiles of different colors can form structures on which colored patterns are ``painted.'' We explore the complexity, in terms of the numbers of unique tile types…

Emerging Technologies · Computer Science 2024-03-12 Phillip Drake , Matthew J. Patitz , Scott M. Summers , Tyler Tracy

Is Winfree's abstract Tile Assembly Model (aTAM) "powerful?" Well, if certain tiles are required to "cooperate" in order to be able to bind to a growing tile assembly (a.k.a., temperature 2 self-assembly), then Turing universal computation…

Emerging Technologies · Computer Science 2012-02-02 Matthew J. Patitz , Robert T. Schweller , Scott M. Summers

We define the Reflexive Tile Assembly Model (RTAM), which is obtained from the abstract Tile Assembly Model (aTAM) by allowing tiles to reflect across their horizontal and/or vertical axes. We show that the class of directed temperature-1…

Computational Geometry · Computer Science 2015-03-13 Jacob Hendricks , Matthew J. Patitz , Trent A. Rogers

The connection between self-assembly and computation suggests that a shape can be considered the output of a self-assembly ``program,'' a set of tiles that fit together to create a shape. It seems plausible that the size of the smallest…

Computational Complexity · Computer Science 2008-06-22 David Soloveichik , Erik Winfree

We prove that if a subset X of the integer Cartesian plane weakly self-assembles at temperature 1 in a deterministic (Winfree) tile assembly system satisfying a natural condition known as *pumpability*, then X is a finite union of doubly…

Computational Complexity · Computer Science 2009-06-18 David Doty , Matthew J. Patitz , Scott M. Summers

In this paper we explore the power of geometry to overcome the limitations of non-cooperative self-assembly. We define a generalization of the abstract Tile Assembly Model (aTAM), such that a tile system consists of a collection of…

Emerging Technologies · Computer Science 2014-08-20 Sándor P. Fekete , Jacob Hendricks , Matthew J. Patitz , Trent A. Rogers , Robert T. Schweller

We prove the computational weakness of a model of tile assembly that has so far resisted many attempts of formal analysis or positive constructions. Specifically, we prove that, in Winfree's abstract Tile Assembly Model, when restricted to…

Computational Complexity · Computer Science 2015-07-31 Pierre-Étienne Meunier , Damien Regnault

In this paper we define the Dupled abstract Tile Assembly Model (DaTAM), which is a slight extension to the abstract Tile Assembly Model (aTAM) that allows for not only the standard square tiles, but also "duple" tiles which are rectangles…

Emerging Technologies · Computer Science 2014-03-10 Jacob Hendricks , Matthew J. Patitz , Trent A. Rogers , Scott M. Summers

In this paper, we investigate shape-assembling power of a tile-based model of self-assembly called the Signal-Passing Tile Assembly Model (STAM). In this model, the glues that bind tiles together can be turned on and off by the binding…

Formal Languages and Automata Theory · Computer Science 2022-06-09 Andrew Alseth , Daniel Hader , Matthew J. Patitz

We show the first asymptotically efficient constructions in the so-called "noncooperative planar tile assembly" model. Algorithmic self-assembly is the study of the local, distributed, asynchronous algorithms ran by molecules to…

Computational Complexity · Computer Science 2021-07-19 Pierre-Etienne Meunier , Damien Regnault

Simulated annealing is an effective and general means of optimization. It is in fact inspired by metallurgy, where the temperature of a material determines its behavior in thermodynamics. Likewise, in simulated annealing, the actions that…

Machine Learning · Computer Science 2020-07-01 Avrim Blum , Chen Dan , Saeed Seddighin

The ability to design and synthesize ever more complicated colloidal particles opens the possibility of self-assembling a zoo of complex structures, including those with one or more self-limited length scales. An undesirable feature of…

Soft Condensed Matter · Physics 2022-03-02 Thomas E. Videbæk , Huang Fang , Daichi Hayakawa , Botond Tyukodi , Michael F. Hagan , W. Benjamin Rogers

In this paper we demonstrate the power of a model of tile self-assembly based on active glues which can dynamically change state. We formulate the Signal-passing Tile Assembly Model (STAM), based on the model of Padilla, Liu, and Seeman to…

Self-assembly is a fundamental process by which supramolecular species form spontaneously from their components. This process is ubiquitous throughout the life chemistry and is central to biological information processing. Algorithms for…

Emerging Technologies · Computer Science 2012-07-06 Abhishek Chhajer , Manish K. Gupta , Sandeep Vasani , Jaley Dholakiya

Self-assembly is one of the prevalent strategies used by living systems to fabricate ensembles of precision nanometer-scale structures and devices. The push for analogous approaches to create synthetic nanomaterials has led to the…

Sequence-directed assembly processes - such as protein folding - allow the assembly of a large number of structures with high accuracy from only a small handful of fundamental building blocks. We aim to explore how efficiently sequence…

Biological Physics · Physics 2025-03-14 Jeremy Guntoro , Thomas Ouldridge